{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T23:12:21Z","timestamp":1784329941923,"version":"3.55.0"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2011,12,28]],"date-time":"2011-12-28T00:00:00Z","timestamp":1325030400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the prevalence of joint\u2010pain comorbidities in individuals with hip or knee osteoarthritis (OA) and to assess the differences in the characteristics of people with and without joint\u2010pain comorbidities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this cross\u2010sectional study, individuals referred to secondary care for treatment of hip\/knee OA completed questionnaires to determine sociodemographic characteristics, disease\u2010related outcomes, and joint\u2010pain comorbidities. Joint\u2010pain comorbidity was defined as pain perceived in a joint, other than the index joint, for more than half of the days in the preceding month. To compare differences in patient\u2010 and disease\u2010related characteristics between participants with and without joint\u2010pain comorbidities, we performed analyses of covariance and logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 401 individuals, 117 with hip OA and 284 with knee OA, returned the questionnaire (82% response rate); the mean \u00b1 SD age was 58 \u00b1 13 years and 58% of the responders were women. Fifty\u2010eight percent of the participants reported symptoms in \u22651 other joint. Participants with joint\u2010pain comorbidities were more likely to be women, less educated, and have more medical comorbidities. Individuals with joint\u2010pain comorbidities reported unfavorable outcomes on pain, functioning, fatigue, distress, and health\u2010related quality of life compared with patients without joint\u2010pain comorbidities (<jats:italic>P &lt;<\/jats:italic> 0.001 for all). Moreover, use of nonsteroidal antiinflammatory drugs (<jats:italic>P<\/jats:italic> = 0.038), opioids (<jats:italic>P<\/jats:italic> = 0.010), and supplements (<jats:italic>P<\/jats:italic> = 0.019) was higher in the group with joint\u2010pain comorbidities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our results indicate that individuals with joint\u2010pain comorbidities represent a clinically relevant and large subgroup of people with OA of the knee or hip. We recommend addressing joint\u2010pain comorbidities in both research and clinical practice.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.20647","type":"journal-article","created":{"date-parts":[[2011,9,27]],"date-time":"2011-09-27T22:35:02Z","timestamp":1317162902000},"page":"54-58","source":"Crossref","is-referenced-by-count":53,"title":["Joint\u2010pain comorbidity, health status, and medication use in hip and knee osteoarthritis: A cross\u2010sectional study"],"prefix":"10.1002","volume":"64","author":[{"given":"Thomas J.","family":"Hoogeboom","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfons A.","family":"den Broeder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart A.","family":"Swierstra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rob A.","family":"de Bie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelia H. M.","family":"van den Ende","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,12,28]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kem118"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2007.11.002"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20324"},{"key":"e_1_2_7_5_2","volume-title":"Osteoarthritis: national clinical guideline for care and management in adults","author":"Conaghan PG","year":"2008"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-002-0603-z"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.16.4.494"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199206000-00002"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/oem.57.5.353"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.3200\/JRLP.139.5.439-457"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10865-005-9011-x"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1983.tb09716.x"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/36.7.786"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.21218"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2009.06.002"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.096164"}],"container-title":["Arthritis Care &amp; Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Facr.20647","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr.20647","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T17:44:29Z","timestamp":1759427069000},"score":1,"resource":{"primary":{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/10.1002\/acr.20647"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12,28]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["10.1002\/acr.20647"],"URL":"https:\/\/doi.org\/10.1002\/acr.20647","archive":["Portico"],"relation":{},"ISSN":["2151-464X","2151-4658"],"issn-type":[{"value":"2151-464X","type":"print"},{"value":"2151-4658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,12,28]]}}}