{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T22:33:20Z","timestamp":1783636400350,"version":"3.55.0"},"reference-count":34,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,7,26]],"date-time":"2013-07-26T00:00:00Z","timestamp":1374796800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"crossref","award":["1-R01-AR-054324-01A1"],"award-info":[{"award-number":["1-R01-AR-054324-01A1"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the relationship between long\u2010term maintenance of moderate to vigorous physical activity (MVPA) and clinical outcomes in fibromyalgia (FM).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with FM (n = 170) received individualized exercise prescriptions and completed baseline and followup physical activity assessments using the Community Health Activities Model Program for Seniors questionnaire at weeks 12, 24, and 36. The primary outcome was the change in the Fibromyalgia Impact Questionnaire\u2010Physical Impairment (FIQ\u2010PI) score. The secondary outcomes included improvements in overall well\u2010being (FIQ total score), pain severity ratings, and depression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Using a threshold increase in MVPA of \u226510 metabolic equivalent hours\/week above usual activities, 27 subjects (15.9%) increased and sustained (SUS\u2010PA), 68 (40%) increased but then declined (UNSUS\u2010PA), and 75 (44.1%) did not achieve (LO\u2010PA) this benchmark. Compared to LO\u2010PA subjects, both SUS\u2010PA and UNSUS\u2010PA subjects reported greater improvement in FIQ\u2010PI (<jats:italic>P<\/jats:italic> &lt; 0.01) and FIQ total score (<jats:italic>P<\/jats:italic> &lt; 0.05). Additionally, the SUS\u2010PA group reported greater improvement in pain severity compared to the LO\u2010PA group (<jats:italic>P<\/jats:italic> &lt; 0.05). However, there were no significant group differences between SUS\u2010PA and UNSUS\u2010PA for any primary or secondary outcome measure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Increased participation in MVPA for at least 12 weeks improved physical function and overall well\u2010being in patients with FM. Although sustained physical activity was not associated with greater clinical benefit compared with unsustained physical activity, these findings also suggest that performing greater volumes of physical activity is not associated with worsening pain in FM. Future research is needed to determine the relationship between sustained MVPA participation and subsequent improvement in patient outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.21980","type":"journal-article","created":{"date-parts":[[2013,2,11]],"date-time":"2013-02-11T16:05:29Z","timestamp":1360598729000},"page":"1211-1218","source":"Crossref","is-referenced-by-count":47,"title":["Effect of Moderate to Vigorous Physical Activity on Long\u2010Term Clinical Outcomes and Pain Severity in Fibromyalgia"],"prefix":"10.1002","volume":"65","author":[{"given":"Anthony S.","family":"Kaleth","sequence":"first","affiliation":[{"name":"Indiana University\u2010Purdue University Indianapolis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandan K.","family":"Saha","sequence":"additional","affiliation":[{"name":"Indiana University Indianapolis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark 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