{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T11:19:33Z","timestamp":1770290373065,"version":"3.49.0"},"reference-count":28,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2014,10,24]],"date-time":"2014-10-24T00:00:00Z","timestamp":1414108800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis Care &amp;amp; Research"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine if functional discharge readiness and mobility following total knee arthroplasty (TKA) for osteoarthritis is delayed after femoral nerve block (FNB) with or without patient\u2010controlled analgesia (PCA) opioid compared with PCA opioid alone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analyzed secondary outcomes from a randomized controlled trial with 200 patients undergoing unilateral TKA. Experimental group 1 received single\u2010injection FNB with intravenous PCA opioid, experimental group 2 received continuous FNB, and the control group received PCA opioid alone. FNB was administered using bupivacaine. Patients followed a structured TKA pathway. Discharge readiness outcomes included achievement of 90\u00b0 knee flexion, independent walking, and stair climbing, and were assessed daily before discharge or day 6, whichever came first. Mobility outcomes included the Timed Up and Go (TUG) test, the 6\u2010Minute Walk Distance (6MWD), and self\u2010reported physical function, and were assessed at weeks 2 and 12. TUG was also assessed on days 3 to 6, postoperation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both FNB groups (77%) were more likely to achieve 90\u00b0 knee flexion compared with the control group (59%); odds ratio (OR) 2.3, 95% confidence interval (95% CI) 1.1, 4.8 for single\u2010injection FNB, and OR 2.3, 95% CI 1.1, 4.9 for continuous FNB. There were no significant differences in independent walking and stair\u2010climbing ability before discharge, TUG, 6MWD, or self\u2010reported physical function, between the FNB groups compared with the control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>After TKA, FNB (single\u2010injection with PCA opioid or continuous) does not delay achievement of 90\u00b0 knee flexion or other measures of functional discharge readiness and mobility compared with PCA opioid alone.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.22361","type":"journal-article","created":{"date-parts":[[2014,4,29]],"date-time":"2014-04-29T12:30:58Z","timestamp":1398774658000},"page":"1688-1694","source":"Crossref","is-referenced-by-count":8,"title":["Functional Discharge Readiness and Mobility Following Total Knee Arthroplasty for Osteoarthritis: A Comparison of Analgesic Techniques"],"prefix":"10.1002","volume":"66","author":[{"given":"Ee\u2010Yuee","family":"Chan","sequence":"first","affiliation":[{"name":"Tan Tock Seng Hospital Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yee\u2010Hong","family":"Teo","sequence":"additional","affiliation":[{"name":"Tan Tock Seng Hospital Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pryseley N.","family":"Assam","sequence":"additional","affiliation":[{"name":"Duke University\/National University of Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marlene","family":"Fransen","sequence":"additional","affiliation":[{"name":"University of Sydney Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,10,24]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Australian Orthopaedic Association. 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