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Differences in lower extremity function (Short Physical Performance Battery [SPPB] and 4\u2010meter walking speed) and upper extremity function (grip strength) by gout status and by hyperuricemia prevalence were estimated in adjusted ordinal logistic regression (SPPB) and linear regression (walking speed and grip strength) models. Lower scores or times signify worse function. The prevalence of poor physical performance (first quartile) by gout and hyperuricemia was estimated using adjusted modified Poisson regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Ten percent of participants reported a history of gout and 21% had hyperuricemia. There was no difference in grip strength by history of gout (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.77). Participants with gout performed worse on the SPPB test; they had 0.77 times (95% confidence interval [95% CI] 0.65, 0.90,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.001) the prevalence odds of a 1\u2010unit increase in SPPB score and were 1.18 times (95% CI 1.07, 1.32,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.002) more likely to have poor SPPB performance. Participants with a history of gout had slower walking speed (mean difference \u22120.03; 95% CI \u22120.05, \u22120.01,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001) and were 1.19 times (95% CI 1.06, 1.34,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.003) more likely to have poor walking speed. Similarly, SPPB score and walking speed, but not grip strength, were worse in participants with hyperuricemia.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Older adults with gout and hyperuricemia are more likely to have worse lower extremity, but not upper extremity, function.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acr.22648","type":"journal-article","created":{"date-parts":[[2015,7,3]],"date-time":"2015-07-03T12:06:38Z","timestamp":1435925198000},"page":"1730-1738","source":"Crossref","is-referenced-by-count":43,"title":["Physical Function, Hyperuricemia, and Gout in Older Adults"],"prefix":"10.1002","volume":"67","author":[{"given":"Bridget Teevan","family":"Burke","sequence":"first","affiliation":[{"name":"Johns Hopkins University, Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"K\u00f6ttgen","sequence":"additional","affiliation":[{"name":"Johns Hopkins University, Baltimore, Maryland, and University of Freiburg  Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Law","sequence":"additional","affiliation":[{"name":"Johns Hopkins University, Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beverly","family":"Gwen Windham","sequence":"additional","affiliation":[{"name":"University of Mississippi Medical Center  Jackson"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorry","family":"Segev","sequence":"additional","affiliation":[{"name":"Johns Hopkins University, Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan N.","family":"Baer","sequence":"additional","affiliation":[{"name":"Johns Hopkins University, Baltimore 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