{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T02:35:44Z","timestamp":1784946944074,"version":"3.55.0"},"reference-count":45,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,4,27]],"date-time":"2016-04-27T00:00:00Z","timestamp":1461715200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Australian Health Management, National Health and Medical Research Council","award":["631717"],"award-info":[{"award-number":["631717"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate whether a 12\u2010week physical therapist\u2013delivered combined pain coping skills training (PCST) and exercise (PCST\/exercise) is more efficacious and cost effective than either treatment alone for knee osteoarthritis (OA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was an assessor\u2010blinded, 3\u2010arm randomized controlled trial in 222 people (73 PCST\/exercise, 75 exercise, and 74 PCST) ages \u226550 years with knee OA. All participants received 10 treatments over 12 weeks plus a home program. PCST covered pain education and training in cognitive and behavioral pain coping skills, exercise comprised strengthening exercises, and PCST\/exercise integrated both. Primary outcomes were self\u2010reported average knee pain (visual analog scale, range 0\u2013100 mm) and physical function (Western Ontario and McMaster Universities Osteoarthritis Index, range 0\u201368) at week 12. Secondary outcomes included other pain measures, global change, physical performance, psychological health, physical activity, quality of life, and cost effectiveness. Analyses were by intent\u2010to\u2010treat methodology with multiple imputation for missing data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 201 participants (91%), 181 participants (82%), and 186 participants (84%) completed week 12, 32, and 52 measurements, respectively. At week 12, there were no significant between\u2010group differences for reductions in pain comparing PCST\/exercise versus exercise (mean difference 5.8 mm [95% confidence interval (95% CI) \u22121.4, 13.0]) and PCST\/exercise versus PCST (6.7 mm [95% CI \u22120.6, 14.1]). Significantly greater improvements in function were found for PCST\/exercise versus exercise (3.7 units [95% CI 0.4, 7.0]) and PCST\/exercise versus PCST (7.9 units [95% CI 4.7, 11.2]). These differences persisted at weeks 32 (both) and 52 (PCST). Benefits favoring PCST\/exercise were seen on several secondary outcomes. Cost effectiveness of PCST\/exercise was not demonstrated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This model of care could improve access to psychological treatment and augment patient outcomes from exercise in knee OA, although it did not appear to be cost effective.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.22744","type":"journal-article","created":{"date-parts":[[2015,9,28]],"date-time":"2015-09-28T12:34:35Z","timestamp":1443443675000},"page":"590-602","source":"Crossref","is-referenced-by-count":167,"title":["Physical Therapist\u2013Delivered Pain Coping Skills Training and Exercise for Knee Osteoarthritis: Randomized Controlled Trial"],"prefix":"10.1002","volume":"68","author":[{"given":"Kim L.","family":"Bennell","sequence":"first","affiliation":[{"name":"University of Melbourne Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmin","family":"Ahamed","sequence":"additional","affiliation":[{"name":"University of Melbourne Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwendolen","family":"Jull","sequence":"additional","affiliation":[{"name":"University of Queensland Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Bryant","sequence":"additional","affiliation":[{"name":"University of Melbourne and Royal Women's Hospital Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Hunt","sequence":"additional","affiliation":[{"name":"University of British Columbia Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew B.","family":"Forbes","sequence":"additional","affiliation":[{"name":"Monash University Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Kasza","sequence":"additional","affiliation":[{"name":"Monash University Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammed","family":"Akram","sequence":"additional","affiliation":[{"name":"Monash University Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Metcalf","sequence":"additional","affiliation":[{"name":"University of Melbourne Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Harris","sequence":"additional","affiliation":[{"name":"Monash University Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thorlene","family":"Egerton","sequence":"additional","affiliation":[{"name":"University of Melbourne Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin A.","family":"Kenardy","sequence":"additional","affiliation":[{"name":"University of Queensland Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael K.","family":"Nicholas","sequence":"additional","affiliation":[{"name":"University of Sydney Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis J.","family":"Keefe","sequence":"additional","affiliation":[{"name":"Duke University Durham North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,4,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-204763"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2013.11.012"},{"key":"e_1_2_7_4_1","first-page":"CD004376","article-title":"Exercise for osteoarthritis of the knee","volume":"9","author":"Fransen M","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2009.06.012"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.21701"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-7894(05)80357-0"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199608)9:4<279::AID-ANR1790090413>3.0.CO;2-6"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2004.03.022"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2011.01.003"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2012.02.023"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.12275"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269215514558567"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2014.05.024"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2012.07.008"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-13-129"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780290816"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.2522\/ptj.20130444"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2015.03.005"},{"key":"e_1_2_7_20_1","first-page":"444","article-title":"Osteoarthritis antirheumatic drug trials. II: tables for calculating sample size for clinical trials","volume":"19","author":"Bellamy N","year":"1992","journal-title":"J Rheumatol"},{"key":"e_1_2_7_21_1","first-page":"1833","article-title":"Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee","volume":"15","author":"Bellamy N","year":"1988","journal-title":"J Rheumatol"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200110)45:5<453::AID-ART365>3.0.CO;2-W"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200108)45:4<384::AID-ART352>3.0.CO;2-0"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-4-19"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(93)90053-4"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/anr.1780320107"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1005548801037"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(83)90125-2"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1348\/014466505X29657"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(85)90465-6"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.3138\/ptc.48.4.257"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2004.022905"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.23823"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwr183"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1191\/0962280202sm304ra"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-6296(01)00086-8"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.2307\/2346405"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e32832ed704"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-12-255"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2012.11.007"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-11-86"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0120042"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.2147\/JMDH.S66746"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.22995"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.23011"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20642"}],"container-title":["Arthritis Care &amp; Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Facr.22744","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Facr.22744","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr.22744","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T16:18:05Z","timestamp":1759421885000},"score":1,"resource":{"primary":{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/10.1002\/acr.22744"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,27]]},"references-count":45,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["10.1002\/acr.22744"],"URL":"https:\/\/doi.org\/10.1002\/acr.22744","archive":["Portico"],"relation":{},"ISSN":["2151-464X","2151-4658"],"issn-type":[{"value":"2151-464X","type":"print"},{"value":"2151-4658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,27]]}}}