{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T05:49:21Z","timestamp":1780638561267,"version":"3.54.1"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,5,8]],"date-time":"2017-05-08T00:00:00Z","timestamp":1494201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["(KAKENHI grant JP15K09535)"],"award-info":[{"award-number":["(KAKENHI grant JP15K09535)"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis Care &amp;amp; Research"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Ultrasonography has been prevalently used as a valid and objective modality for joint examination in patients with rheumatoid arthritis (RA). This study aimed to examine and compare the concordance between ultrasound, clinical assessment, and patient\u2010reported assessment of joint synovitis in RA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty patients with RA (84% female, median age 69 years, median disease duration 31 months, and median Disease Activity Score in 28 joints 3.8) completed the self\u2010evaluation of joint symptoms, including pain and considerable stiffness in the (proximal) interphalangeal, metacarpophalangeal, wrist, elbow, shoulder, knee, and ankle joints. These joints were also examined by a physician in order to assess the presence of tenderness or swelling; the presence of imaging synovitis was assessed by ultrasonography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In a total of 1,492 evaluated joints, symptoms (pain and stiffness), tenderness, and swelling were noted in 288 (19.3%), 182 (12.2%), and 220 (14.7%) joints, respectively, while ultrasound indicated synovitis in 317 (21.2%) joints. Overall concordance with ultrasound findings was lowest for joint tenderness (\u03ba\u2009=\u20090.30), followed by symptoms (\u03ba\u2009=\u20090.39), and by swelling (\u03ba\u2009=\u20090.43), irrespective of the evaluated joint, except for the elbow. Moreover, the percentages of inflamed joints detected only on the basis of symptoms, tenderness, or swelling were 18.6%, 2.2%, and 8.5%, respectively, of all joints with signs of synovitis on ultrasonography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Joint swelling showed the best concordance with ultrasonography, followed by patient\u2010reported joint symptoms, and joint tenderness. Joint symptoms, rather than tenderness evaluation, may be a better clinical indicator of synovitis in RA patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.23006","type":"journal-article","created":{"date-parts":[[2016,8,26]],"date-time":"2016-08-26T14:18:26Z","timestamp":1472221106000},"page":"801-806","source":"Crossref","is-referenced-by-count":26,"title":["Concordance of Patient\u2010Reported Joint Symptoms, Physician\u2010Examined Arthritic Signs, and Ultrasound\u2010Detected Synovitis in Rheumatoid Arthritis"],"prefix":"10.1002","volume":"69","author":[{"given":"Ayako","family":"Hirata","sequence":"first","affiliation":[{"name":"Toho University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takehisa","family":"Ogura","sequence":"additional","affiliation":[{"name":"Toho University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norihide","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Toho University 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