{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:59:41Z","timestamp":1792803581245,"version":"4.5.0"},"reference-count":34,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2017,6,7]],"date-time":"2017-06-07T00:00:00Z","timestamp":1496793600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"national public"},{"name":"Programme Hospitalier de Recherche Clinique","award":["AOM04023"],"award-info":[{"award-number":["AOM04023"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare a physical therapy program to usual care of systemic sclerosis (SSc) patients on disability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 12\u2010month followup, parallel\u2010group randomized controlled trial involving a modified Zelen design was conducted in 4 tertiary\u2010care hospitals. Patients were enrolled if they had a disability rating \u22650.5 on the Health Assessment Questionnaire disability index (HAQ DI) or symptoms of decreased mouth opening or limited range of motion of at least 1 joint. The experimental intervention (n\u2009=\u2009112, of which 110 were analyzed) was a 1\u2010month personalized supervised physical therapy program provided by trained care providers followed by home sessions. The comparator (n\u2009=\u2009108, and all 108 were analyzed) was usual care that could include ambulatory physical therapy. The primary outcome was the HAQ DI score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was no statistically significant difference in disability at 12 months (HAQ DI score between\u2010group difference \u22120.01 [95% confidence interval (95% CI) \u22120.15, 0.13];\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.86). Disability was reduced at 1 month for patients in the physical therapy group (HAQ DI between\u2010group difference \u22120.14 [95% CI \u22120.24, \u22120.03];\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.01); at 6 months the HAQ DI score between\u2010group difference was \u22120.12 (95% CI \u22120.23, 0.01);\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.054. There was a statistically significant difference for hand mobility and function, and for pain, at 1 month. Microstomia was lower in the physical therapy group at 1, 6, and 12 months (between\u2010group difference at 12 months 1.62 [95% CI 0.32, 2.93];\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.01). No differences in adverse effects were observed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A personalized physical therapy program did not reduce disability at 12 months but had short\u2010term benefits for patients with SSc.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acr.23098","type":"journal-article","created":{"date-parts":[[2016,10,7]],"date-time":"2016-10-07T08:59:58Z","timestamp":1475830798000},"page":"1050-1059","source":"Crossref","is-referenced-by-count":68,"title":["Personalized Physical Therapy Versus Usual Care for Patients With Systemic Sclerosis: A Randomized Controlled Trial"],"prefix":"10.1002","volume":"69","author":[{"given":"Fran\u00e7ois","family":"Rannou","sequence":"first","affiliation":[{"name":"AP\u2010HP Cochin Hospital, Universit\u00e9 Paris Descartes Sorbonne Paris Cit\u00e9, and INSERM U1153 Paris 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University Medical Center, University of Lille 2 Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Hachulla","sequence":"additional","affiliation":[{"name":"Reference Center for Rare Diseases, Lille University Medical Center, University of Lille 2 Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipe","family":"Thoumie","sequence":"additional","affiliation":[{"name":"AP\u2010HP Rothschild Hospital and Pierre and Marie Curie University Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Cabane","sequence":"additional","affiliation":[{"name":"AP\u2010HP Saint\u2010Antoine Hospital and Pierre and Marie Curie University Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Chatelus","sequence":"additional","affiliation":[{"name":"H\u00f4pital Hautepierre, F\u00e9d\u00e9ration de M\u00e9decine Translationnelle de Strasbourg, UMR 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