{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T11:25:43Z","timestamp":1791890743518,"version":"4.3.4"},"reference-count":44,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,8,29]],"date-time":"2017-08-29T00:00:00Z","timestamp":1503964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis Care &amp;amp; Research"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The nature and impact of food and other external triggers in recurrences of Beh\u00e7et's disease (BD)\u2010related oral ulcers (OUs) remain unknown. This survey investigated dietary and nondietary triggers of BD\u2010related OU recurrences.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with BD who were followed in 7 French hospital departments completed a self\u2010administered patient questionnaire. General and specific dietary triggering factors were sought in open questions. The questionnaire also included closed questions, notably to evaluate the effect of 6 general triggering situations and 24 selected foods. The results were expressed as number (percentage) of positive responses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 101 questionnaires distributed, 81 were usable. Among the 81 patients, 96% fulfilled the International Criteria for Beh\u00e7et's Disease classification criteria, and 53% qualified their OU recurrences during the previous 12 months as very discomforting or discomforting. For the 6 general situations suggested, 50 patients (62%) declared \u22651 as a \u201csure\u201d trigger of OU recurrences. In both open and closed questions, the most frequent triggers were fatigue\/stress (37\u201347% of patients) and food (32\u201335%). Among the 24 suggested foods, nuts (48%), pineapple (42%), peanuts (32%), Emmental cheese (30%), almonds (23%), lemons (22%), and other cheeses (21%) were the most frequently reported. The corresponding open question gave consistent findings but with lower frequencies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Most patients can identify triggers of recurring BD\u2010related OUs, with fatigue\/stress and food representing the most frequent triggers. The management of OU must consider such external factors. The histamine\u2010rich or \u2010liberating properties of the commonly cited OU\u2010triggering foods suggest a hyperreactivity mechanism.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.23155","type":"journal-article","created":{"date-parts":[[2016,11,18]],"date-time":"2016-11-18T15:23:04Z","timestamp":1479482584000},"page":"1429-1436","source":"Crossref","is-referenced-by-count":24,"title":["Dietary and Nondietary Triggers of Oral Ulcer Recurrences in Beh\u00e7et's Disease"],"prefix":"10.1002","volume":"69","author":[{"given":"Geoffroy","family":"Volle","sequence":"first","affiliation":[{"name":"Hospital Saint\u2010Louis, University Paris Diderot Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Baptiste","family":"Fraison","sequence":"additional","affiliation":[{"name":"Hospital Saint\u2010Louis, University Paris Diderot, Paris, and Hospital Jean Verdier, University Leonard de Vinci Bondy 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