{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T18:50:35Z","timestamp":1780685435663,"version":"3.54.1"},"reference-count":31,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,11,2]],"date-time":"2017-11-02T00:00:00Z","timestamp":1509580800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000341","name":"Arthritis Research UK","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000341","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000856","name":"Colt Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000856","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011720","name":"British Pain Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011720","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate whether associations between pain and the additional symptoms associated with fibromyalgia are different in persons with chronic widespread pain (<jats:styled-content style=\"fixed-case\">CWP<\/jats:styled-content>) compared to multisite pain (<jats:styled-content style=\"fixed-case\">MSP<\/jats:styled-content>), with or without joint areas.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Six studies were used: 1958 British birth cohort, Epidemiology of Functional Disorders, Kid Low Back Pain, Managing Unexplained Symptoms (Chronic Widespread Pain) in Primary Care: Involving Traditional and Accessible New Approaches, Study of Health and its Management, and Women's Health Study (<jats:styled-content style=\"fixed-case\">WHEST<\/jats:styled-content>; females). <jats:styled-content style=\"fixed-case\">MSP<\/jats:styled-content> was defined as the presence of pain in \u22658 body sites in adults (\u226510 sites in children) indicated on 4\u2010view body manikins, conducted first to include joints (positive joints) and second without (negative joints). The relationship between pain and fatigue, sleep disturbance, somatic symptoms, and mood impairment was assessed using logistic regression. Results are presented as odds ratios (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>s) with 95% confidence intervals (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>s).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 34,818 participants across the study populations (adults age range 42\u201356 years, male 43\u201351% [excluding <jats:styled-content style=\"fixed-case\">WHEST<\/jats:styled-content>], and <jats:styled-content style=\"fixed-case\">CWP<\/jats:styled-content> prevalence 12\u201317%). Among those reporting <jats:styled-content style=\"fixed-case\">MSP<\/jats:styled-content>, the proportion reporting <jats:styled-content style=\"fixed-case\">CWP<\/jats:styled-content> ranged between 62% and 76%. Among those reporting the symptoms associated with fibromyalgia, there was an increased likelihood of reporting pain, the magnitude of which was similar regardless of the definition used. For example, within <jats:styled-content style=\"fixed-case\">WHEST<\/jats:styled-content>, reporting moderate\/severe fatigue (Chalder fatigue scale 4\u201311) was associated with a &gt;5\u2010fold increase in likelihood of reporting pain (<jats:styled-content style=\"fixed-case\">CWP OR<\/jats:styled-content> 5.2 [95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 3.9\u20136.9], <jats:styled-content style=\"fixed-case\">MSP<\/jats:styled-content>\u2013positive joints <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 6.5 [95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 5.0\u20138.6], and <jats:styled-content style=\"fixed-case\">MSP<\/jats:styled-content>\u2013negative joints <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 6.5 [95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 4.7\u20139.0]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This large\u2010scale study demonstrates that regardless of the pain definition used, the magnitude of association between pain and other associated symptoms of fibromyalgia is similar. This finding supports the continued collection of both when classifying fibromyalgia, but highlights the fact that pain may not require to follow the definition outlined within the 1990 American College of Rheumatology criteria.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.23214","type":"journal-article","created":{"date-parts":[[2017,2,9]],"date-time":"2017-02-09T14:46:07Z","timestamp":1486651567000},"page":"1878-1886","source":"Crossref","is-referenced-by-count":16,"title":["Impact of Moving From a Widespread to Multisite Pain Definition on Other Fibromyalgia Symptoms"],"prefix":"10.1002","volume":"69","author":[{"given":"Linda E.","family":"Dean","sequence":"first","affiliation":[{"name":"University of Aberdeen Aberdeen UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lesley","family":"Arnold","sequence":"additional","affiliation":[{"name":"University of Cincinnati Cincinnati 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