{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T18:50:09Z","timestamp":1792608609364,"version":"4.5.0"},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,4,2]],"date-time":"2018-04-02T00:00:00Z","timestamp":1522627200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp;amp; Research"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>There is an increasing emphasis on the early identification and treatment of ankylosing spondylitis (<jats:styled-content style=\"fixed-case\">AS<\/jats:styled-content>) of which the hallmark is sacroiliitis. Patients with inflammatory bowel disease (<jats:styled-content style=\"fixed-case\">IBD<\/jats:styled-content>) are at increased risk of <jats:styled-content style=\"fixed-case\">AS<\/jats:styled-content> and often receive computed tomography (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) scans of their abdomen, affording clinicians the opportunity to determine the presence of sacroiliitis. Previous studies using <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> have relied only on the radiologist's gestalt or a nonvalidated adaptation of the modified New York criteria. Our aim is to assess the prevalence of sacroiliitis in <jats:styled-content style=\"fixed-case\">IBD<\/jats:styled-content> using a validated screening tool and to determine how frequently these patients are referred for rheumatologic evaluation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with <jats:styled-content style=\"fixed-case\">IBD<\/jats:styled-content> were recruited from an <jats:styled-content style=\"fixed-case\">IBD<\/jats:styled-content> clinic. Control patients were recruited from a urology clinic and were confirmed to be without back pain, spondylitis, psoriasis, colitis, or uveitis by chart review. <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> scans were read by 2 blinded readers and sacroiliitis was defined by the presence of ankylosis or a total erosion score of \u22653.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> scans were available in 233 Crohn's disease (<jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>) patients, 83 ulcerative colitis (<jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content>) patients, and 108 control patients, and sacroiliitis was seen in 15%, 16.9%, and 5.6% of patients, respectively. The prevalence was higher in patients with <jats:styled-content style=\"fixed-case\">IBD<\/jats:styled-content> than in controls (<jats:italic>P<\/jats:italic> = 0.007), with no significant difference between <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content> patients. Of the 49 <jats:styled-content style=\"fixed-case\">IBD<\/jats:styled-content> patients found to have sacroiliitis by <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> scan, only 5 had been referred to a rheumatologist.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There is a 3\u2010fold higher prevalence of sacroiliitis in <jats:styled-content style=\"fixed-case\">IBD<\/jats:styled-content> compared with controls. Despite a growing awareness of this increased prevalence, many patients are not referred to a rheumatologist.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.23323","type":"journal-article","created":{"date-parts":[[2017,7,21]],"date-time":"2017-07-21T16:17:42Z","timestamp":1500653862000},"page":"807-810","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Prevalence of Sacroiliitis in Inflammatory Bowel Disease Using a Standardized Computed Tomography Scoring System"],"prefix":"10.1002","volume":"70","author":[{"given":"Jonathan","family":"Chan","sequence":"first","affiliation":[{"name":"Toronto Western Hospital University of Toronto, Toronto, Ontario, Canada and University of British Columbia Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismail","family":"Sari","sequence":"additional","affiliation":[{"name":"Toronto Western Hospital and University of Toronto, Toronto, Ontario, Canada and Dokuz Eylul University School of Medicine Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Salonen","sequence":"additional","affiliation":[{"name":"Toronto Western Hospital Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark S.","family":"Silverberg","sequence":"additional","affiliation":[{"name":"Zane Cohen Centre for Digestive Diseases Mount Sinai Hospital and University of Toronto Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigil","family":"Haroon","sequence":"additional","affiliation":[{"name":"Toronto Western Hospital and University of Toronto Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert D.","family":"Inman","sequence":"additional","affiliation":[{"name":"Toronto Western Hospital and University of Toronto Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,4,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.42.3.387"},{"key":"e_1_2_8_3_1","first-page":"373","article-title":"The arthritis of ulcerative colitis: clinical and genetic aspects","volume":"19","author":"Scarpa R","year":"1992","journal-title":"J Rheumatol"},{"key":"e_1_2_8_4_1","first-page":"518","article-title":"Low back pain, sacroiliitis, and the relationship with HLA\u2010B27 in Crohn's disease","volume":"30","author":"Steer S","year":"2003","journal-title":"J Rheumatol"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00204098"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-011-9832-8"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.5009\/gnl.2010.4.3.338"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2008.03868.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.24762"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12680"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.33466"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/02841850902914099"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.151.2.6709915"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s776-002-8407-1"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.150939"}],"container-title":["Arthritis Care &amp; 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