{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T02:07:26Z","timestamp":1792030046239,"version":"4.4.0"},"reference-count":47,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,3,7]],"date-time":"2018-03-07T00:00:00Z","timestamp":1520380800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100009471","name":"EkstraStiftelsen Helse og Rehabilitering","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009471","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2018,5]]},"abstract":"Objective<\/jats:title>To describe physical functioning, pain, and health\u2010related quality of life (HRQ<\/jats:styled-content>oL) in adults with juvenile idiopathic arthritis (JIA<\/jats:styled-content>), investigate changes over time, and identify predictors of poorer HRQ<\/jats:styled-content>oL after 30 years of disease.<\/jats:p><\/jats:sec>Methods<\/jats:title>Patients (n = 176) clinically examined after 15 years were reassessed using the Health Assessment Questionnaire disability index (HAQ DI<\/jats:styled-content>), the visual analog scale pain subscale (VAS<\/jats:styled-content> pain), and the Medical Outcomes Study Short Form 36 (SF<\/jats:styled-content>\u201036) after 23 years and 30 years. Patients with signs of active disease after a minimum of 15 years were clinically examined again at 30 years. Patients were compared to matched controls.<\/jats:p><\/jats:sec>Results<\/jats:title>At the 30\u2010year followup, 82 patients (47%) had HAQ DI<\/jats:styled-content> scores >0, and the median VAS<\/jats:styled-content> pain score in patients was 0.6 (range 0\u201310). Patients had lower SF<\/jats:styled-content>\u201036 physical component summary (PCS<\/jats:styled-content>) scores compared with controls (P<\/jats:italic> < 0.001), and this was evident for patients both with and without clinical remission (P<\/jats:italic> \u2264 0.01). No group differences were found in SF<\/jats:styled-content>\u201036 mental component summary scores. Patients also scored worse than controls on all SF<\/jats:styled-content>\u201036 subscales (P<\/jats:italic> \u2264 0.01) except mental health. PCS<\/jats:styled-content> scores worsened significantly between the 15\u2010 and 30\u2010year followup time points (P<\/jats:italic> = 0.001). Worse HAQ DI<\/jats:styled-content>, VAS<\/jats:styled-content> pain, and patient's global assessment of well\u2010being scores, and receiving disability\/social living allowance at 30 years, were correlated with lower PCS<\/jats:styled-content> scores. Worse HAQ DI<\/jats:styled-content>, patient's global assessment of well\u2010being, and VAS<\/jats:styled-content> fatigue scores at 15\u2010year followup predicted lower PCS<\/jats:styled-content> scores at 30\u2010year followup.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>JIA<\/jats:styled-content> had a detrimental effect on physical HRQ<\/jats:styled-content>oL as measured by the PCS<\/jats:styled-content> of the SF<\/jats:styled-content>\u201036. The strongest correlates were physical disability, pain, fatigue, well\u2010being, and receiving disability\/social living allowance.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.23327","type":"journal-article","created":{"date-parts":[[2017,7,21]],"date-time":"2017-07-21T16:18:20Z","timestamp":1500653900000},"page":"741-749","source":"Crossref","is-referenced-by-count":84,"title":["Physical Functioning, Pain, and Health\u2010Related Quality of Life in Adults With Juvenile Idiopathic Arthritis: A Longitudinal 30\u2010Year Followup Study"],"prefix":"10.1002","volume":"70","author":[{"given":"Anita","family":"Tollisen","sequence":"first","affiliation":[{"name":"Oslo University Hospital, Rikshospitalet and Lovisenberg Diaconal Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne M.","family":"Selvaag","sequence":"additional","affiliation":[{"name":"Oslo University Hospital, Rikshospitalet Oslo 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