{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T21:37:56Z","timestamp":1790890676396,"version":"4.1.0"},"reference-count":49,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,5,6]],"date-time":"2018-05-06T00:00:00Z","timestamp":1525564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U54\u2010GM\u2010104941"],"award-info":[{"award-number":["U54\u2010GM\u2010104941"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21\u2010AR\u2010071079"],"award-info":[{"award-number":["R21\u2010AR\u2010071079"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Evidence of physical function difficulties, such as difficulty rising from a chair, may limit daily walking for people with knee osteoarthritis (OA). The purpose of this study was to identify minimum performance thresholds on clinical tests of physical function predictive to walking \u22656,000 steps\/day. This benchmark is known to discriminate people with knee OA who develop functional limitation over time from those who do not.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using data from the Osteoarthritis Initiative, we quantified daily walking as average steps\/day from an accelerometer (Actigraph GT1M) worn for \u226510 hours\/day over 1 week. Physical function was quantified using 3 performance\u2010based clinical tests: 5 times sit\u2010to\u2010stand test, walking speed (tested over 20 meters), and 400\u2010meter walk test. To identify minimum performance thresholds for daily walking, we calculated physical function values corresponding to high specificity (80\u201395%) to predict walking \u22656,000 steps\/day.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 1,925 participants (mean \u00b1 SD age 65.1 \u00b1 9.1 years, mean \u00b1 SD body mass index 28.4 \u00b1 4.8 kg\/m<jats:sup>2<\/jats:sup>, and 55% female) with valid accelerometer data, 54.9% walked \u22656,000 steps\/day. High specificity thresholds of physical function for walking \u22656,000 steps\/day ranged 11.4\u201314.0 seconds on the 5 times sit\u2010to\u2010stand test, 1.13\u20131.26 meters\/second for walking speed, or 315\u2013349 seconds on the 400\u2010meter walk test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Not meeting these minimum performance thresholds on clinical tests of physical function may indicate inadequate physical ability to walk \u22656,000 steps\/day for people with knee OA. Rehabilitation may be indicated to address underlying impairments limiting physical function.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.23448","type":"journal-article","created":{"date-parts":[[2017,10,17]],"date-time":"2017-10-17T18:16:43Z","timestamp":1508264203000},"page":"1005-1011","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Minimum Performance on Clinical Tests of Physical Function to Predict Walking 6,000 Steps\/Day in Knee Osteoarthritis: An Observational Study"],"prefix":"10.1002","volume":"70","author":[{"given":"Hiral","family":"Master","sequence":"first","affiliation":[{"name":"University of Delaware Newark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise M.","family":"Thoma","sequence":"additional","affiliation":[{"name":"University of Delaware Newark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meredith 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