{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T17:33:24Z","timestamp":1788629604000,"version":"build-2803163510"},"reference-count":50,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2018,8,27]],"date-time":"2018-08-27T00:00:00Z","timestamp":1535328000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["1U01DP005119"],"award-info":[{"award-number":["1U01DP005119"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004330","name":"GlaxoSmithKline","doi-asserted-by":"publisher","award":["grant GHO\u201011\u20103366"],"award-info":[{"award-number":["grant GHO\u201011\u20103366"]}],"id":[{"id":"10.13039\/100004330","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp;amp; Research"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To use multidomain functional assessment, which is commonly performed in geriatric patients but is novel in patients with systemic lupus erythematosus (\n                      <jats:styled-content style=\"fixed-case\">SLE<\/jats:styled-content>\n                      ), to better understand functional impairment in patients with\n                      <jats:styled-content style=\"fixed-case\">SLE<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We recruited 60 adult participants (aged 20\u201339 years [26.7%], 40\u201359 years [50.0%], and \u226560 years [23.3%]; 80.0% African American and 90.0% female) from an existing cohort of\n                      <jats:styled-content style=\"fixed-case\">SLE<\/jats:styled-content>\n                      patients. During in\u2010person visits (from October 2016 to April 2017), we evaluated physical performance (range 0\u20134, with higher scores indicating better performance), cognitive performance (5 fluid cognition domains; adjusted T scores), and self\u2010reported measures including physical functioning (T scores), activities of daily living (\n                      <jats:styled-content style=\"fixed-case\">ADL<\/jats:styled-content>\n                      s), falls, and life\u2010space mobility.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In the\n                      <jats:styled-content style=\"fixed-case\">SLE<\/jats:styled-content>\n                      patients, the mean balance score (3.7) and gait speed score (3.4) were high, while the\u00a0mean lower body strength score was low (1.8). Cognitive performance was average (score of 5.0) for episodic (47.7) and working (48.6) memory and low average for cognitive flexibility (43.7), processing speed (42.6), and attention\/inhibitory control (38.8 [&gt;1\n                      <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\n                      below average]) when compared with healthy individuals of the same age, sex, race, ethnicity, and education level. Most participants reported the ability to independently perform basic\n                      <jats:styled-content style=\"fixed-case\">ADL<\/jats:styled-content>\n                      s, but many reported the inability to independently perform instrumental\n                      <jats:styled-content style=\"fixed-case\">ADL<\/jats:styled-content>\n                      s. Nearly half (45.0%) of participants reported falling in the prior year. Only 40.0% reported unlimited ability to travel without the help of another person. Scores generally did not differ substantially according to age.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Our results suggest a high prevalence of impairment across multiple domains of function in\n                      <jats:styled-content style=\"fixed-case\">SLE<\/jats:styled-content>\n                      patients of all ages, similar to or exceeding the prevalence observed in much older geriatric populations. Further research into the added value of geriatric assessment in routine care for\n                      <jats:styled-content style=\"fixed-case\">SLE<\/jats:styled-content>\n                      is warranted.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acr.23507","type":"journal-article","created":{"date-parts":[[2018,1,9]],"date-time":"2018-01-09T21:38:19Z","timestamp":1515533899000},"page":"1469-1477","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Geriatric Assessment of Physical and Cognitive Functioning in a Diverse Cohort of Systemic Lupus Erythematosus Patients: A Pilot Study"],"prefix":"10.1002","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0809-8981","authenticated-orcid":false,"given":"Laura","family":"Plantinga","sequence":"first","affiliation":[{"name":"Emory University Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin D.","family":"Tift","sequence":"additional","affiliation":[{"name":"Edward Via College of Osteopathic Medicine Spartanburg South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charmayne","family":"Dunlop\u2010Thomas","sequence":"additional","affiliation":[{"name":"Emory University Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Sam Lim","sequence":"additional","affiliation":[{"name":"Emory University Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Barrett Bowling","sequence":"additional","affiliation":[{"name":"Durham Veterans Affairs Geriatric Research Education and Clinical Center Durham Veterans Affairs Medical Center, and Duke University Durham North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6832-7291","authenticated-orcid":false,"given":"Cristina","family":"Drenkard","sequence":"additional","affiliation":[{"name":"Emory University Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,8,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.130046"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22399"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.20409"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.23339"},{"key":"e_1_2_7_6_1","first-page":"1706","article-title":"How does quality of life of patients with systemic lupus erythematosus compare with that of other common chronic illnesses?","volume":"32","author":"Jolly M","year":"2005","journal-title":"J Rheumatol"},{"key":"e_1_2_7_7_1","first-page":"1825","article-title":"Clinical course of cognitive dysfunction in systemic lupus erythematosus","volume":"21","author":"Hanly JG","year":"1994","journal-title":"J\u00a0Rheumatol"},{"key":"e_1_2_7_8_1","first-page":"562","article-title":"Cognitive impairment in patients with systemic lupus erythematosus","volume":"19","author":"Hanly JG","year":"1992","journal-title":"J Rheumatol"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1076\/clin.15.4.498.1882"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.27404"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/0961203310382430"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1532-5415.2003.51174.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22032"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2014-0180"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgo.2016.02.007"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/lupus-2016-000186"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/lupus-2016-000161"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/0961203317693095"},{"key":"e_1_2_7_19_1","volume-title":"International classification of functioning, disability and health: ICF: short version, Short version","author":"World Health Organization","year":"2001"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.38239"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2013.04.003"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780400928"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"e_1_2_7_24_1","unstructured":"Northwestern University.Cognition Measures: NIH Toobox Cognition Batteries.2017. 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