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The Childhood Arthritis and Rheumatology Research Alliance (CARRA<\/jats:styled-content>) developed consensus treatment plans (CTP<\/jats:styled-content>s) for CAU<\/jats:styled-content> for the purpose of reducing practice variability and allowing future comparison of treatments using comparative effectiveness analysis techniques.<\/jats:p><\/jats:sec>Methods<\/jats:title>A core group of pediatric rheumatologists, ophthalmologists with uveitis expertise, and a lay advisor comprised the CARRA<\/jats:styled-content> uveitis workgroup that performed a literature review on pharmacologic treatments, held teleconferences, and developed a case\u2010based survey administered to the CARRA<\/jats:styled-content> membership to delineate treatment practices. We held 3 face\u2010to\u2010face consensus meetings using nominal group technique to develop CTP<\/jats:styled-content>s.<\/jats:p><\/jats:sec>Results<\/jats:title>The survey identified areas of treatment practice variability. We developed 2 CTP<\/jats:styled-content>s for the treatment of CAU<\/jats:styled-content>, case definitions, and monitoring parameters. The first CTP<\/jats:styled-content> is directed at children who are naive to steroid\u2010sparing medication, and the second at children initiating biologic therapy, with options for methotrexate, adalimumab, and infliximab. We defined a core data set and outcome measures, with data collection at 3 and 6 months after therapy initiation. The CARRA<\/jats:styled-content> membership voted to accept the CTP<\/jats:styled-content>s with a >95% approval (n = 233).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Using consensus methodology, 2 standardized CTP<\/jats:styled-content>s were developed for systemic immunosuppressive treatment of CAU<\/jats:styled-content>. These CTP<\/jats:styled-content>s are not meant as treatment guidelines, but are designed for further pragmatic research within the CARRA<\/jats:styled-content> research network. Use of these CTP<\/jats:styled-content>s in a prospective comparison effectiveness study should improve outcomes by identifying best practice options.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.23610","type":"journal-article","created":{"date-parts":[[2018,5,28]],"date-time":"2018-05-28T07:55:05Z","timestamp":1527494105000},"page":"482-491","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":83,"title":["Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans for Juvenile Idiopathic Arthritis\u2013Associated and Idiopathic Chronic Anterior Uveitis"],"prefix":"10.1002","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9552-6464","authenticated-orcid":false,"given":"Sheila T.","family":"Angeles\u2010Han","sequence":"first","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center and University of Cincinnati Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mindy S.","family":"Lo","sequence":"additional","affiliation":[{"name":"Boston Children's Hospital and Harvard Medical School Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren A.","family":"Henderson","sequence":"additional","affiliation":[{"name":"Boston Children's Hospital and Harvard Medical School Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa A.","family":"Lerman","sequence":"additional","affiliation":[{"name":"The Children's Hospital of Philadelphia Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie","family":"Abramson","sequence":"additional","affiliation":[{"name":"Vermont Children's Hospital and University of Vermont Medical Center Burlington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley\u00a0M.","family":"Cooper","sequence":"additional","affiliation":[{"name":"Children's Mercy Kansas City Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam F.","family":"Parsa","sequence":"additional","affiliation":[{"name":"University of California Los Angeles"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence S.","family":"Zemel","sequence":"additional","affiliation":[{"name":"Connecticut Children's Medical Center Hartford Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tova","family":"Ronis","sequence":"additional","affiliation":[{"name":"Children's National Health System Washington DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Beukelman","sequence":"additional","affiliation":[{"name":"University of Alabama at Birmingham"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Cox","sequence":"additional","affiliation":[{"name":"parent partner Camas Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.\u00a0Nida","family":"Sen","sequence":"additional","affiliation":[{"name":"National Eye Institute, National Institutes of Health Bethesda Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary N.","family":"Holland","sequence":"additional","affiliation":[{"name":"Stein Eye Institute and David Geffen School of Medicine University of California Los Angeles"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hermine I.","family":"Brunner","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center and University of Cincinnati Cincinnati Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Lasky","sequence":"additional","affiliation":[{"name":"Randall Children's Hospital at Legacy Emmanuel Portland Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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