{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T04:46:46Z","timestamp":1773982006224,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,8,13]],"date-time":"2019-08-13T00:00:00Z","timestamp":1565654400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp;amp; Research"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To establish whether there is a relationship between the frequency and severity of different types of childhood maltreatment and adulthood arthritis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Analysis of the 2012 Canadian Community Health Survey\u2013Mental Health included 21,889 respondents ages <jats:bold>\u2265<\/jats:bold>18 years. Severity and frequency of childhood physical abuse (CPA), and childhood sexual abuse (CSA), and the frequency of childhood exposure to intimate partner violence (CEIPV) were assessed by asking about \u201cthings that may have happened to you before you were 16 in your school, in your neighborhood, or in your family.\u201d Respondents were also asked about chronic conditions diagnosed by a health professional, including arthritis. Covariates were sociodemographic characteristics, health risk variables (e.g., obesity), mental disorders, and a count of other chronic conditions. Multivariate logistic regression analysis was used to examine associations between childhood maltreatment and arthritis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 17.5% of respondents reported arthritis. A higher prevalence of arthritis was observed for those who had experienced severe and\/or frequent childhood maltreatment (32% for CPA and 27% for both CSA and CEIPV). These relationships persisted after controlling for sociodemographic variables. After controlling for all covariates, arthritis remained independently associated with severe and\/or frequent CPA (dose\u2010response relationship) and frequent CEIPV.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We found that the greater the frequency and severity of childhood maltreatment, the greater the magnitude of association with arthritis. This might reflect the role of the enduring immune and metabolic abnormalities and chronic inflammation associated with childhood maltreatment in the etiopathogensis of osteoarthritis (OA) or be an indicator of the role of joint injury in causing OA.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.23776","type":"journal-article","created":{"date-parts":[[2018,10,17]],"date-time":"2018-10-17T05:07:04Z","timestamp":1539752824000},"page":"1366-1371","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Childhood Maltreatment as a Risk Factor for Arthritis: Findings From a Population\u2010Based Survey of Canadian Adults"],"prefix":"10.1002","volume":"71","author":[{"given":"Elizabeth M.","family":"Badley","sequence":"first","affiliation":[{"name":"Krembil Research Institute, University Health Network, and the University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margot","family":"Shields","sequence":"additional","affiliation":[{"name":"Centre for Surveillance and Applied Research Public Health Agency of Canada  Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siobhan","family":"O'Donnell","sequence":"additional","affiliation":[{"name":"Centre for Surveillance and Applied Research Public Health Agency of Canada  Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendy E.","family":"Hovdestad","sequence":"additional","affiliation":[{"name":"Centre for Surveillance and Applied Research Public Health Agency of Canada  Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lil","family":"Tonmyr","sequence":"additional","affiliation":[{"name":"Centre for Surveillance and Applied Research Public Health Agency of Canada  Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,8,13]]},"reference":[{"key":"e_1_2_3_2_1","first-page":"10","article-title":"Child abuse and physical health in adulthood","volume":"27","author":"Afifi TO","year":"2016","journal-title":"Health Rep"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chiabu.2007.01.003"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2009.01.034"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.24871"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1041610215001672"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00406-005-0624-4"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/acps.12217"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2011.08.019"},{"key":"e_1_2_3_10_1","volume-title":"Mental health user guide","author":"Canadian Community Health Survey","year":"2013"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S107549"},{"key":"e_1_2_3_12_1","unstructured":"American Psychiatric Association.Diagnostic and Statistical Manual of Mental Disorders (4th ed) (DSM\u2010IV).Washington DC:APA;1994."},{"key":"e_1_2_3_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2016.136"},{"key":"e_1_2_3_14_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/343746"},{"key":"e_1_2_3_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.39842"},{"key":"e_1_2_3_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2014.01.004"},{"key":"e_1_2_3_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chiabu.2016.03.007"},{"key":"e_1_2_3_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.18.2020"},{"key":"e_1_2_3_19_1","first-page":"340","article-title":"Validation of a surveillance case definition for arthritis","volume":"32","author":"Sacks JJ","year":"2005","journal-title":"J Rheumatol"}],"container-title":["Arthritis Care &amp; Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Facr.23776","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr.23776","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/acr.23776","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr.23776","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T16:54:08Z","timestamp":1759424048000},"score":1,"resource":{"primary":{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/10.1002\/acr.23776"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,13]]},"references-count":18,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1002\/acr.23776"],"URL":"https:\/\/doi.org\/10.1002\/acr.23776","archive":["Portico"],"relation":{},"ISSN":["2151-464X","2151-4658"],"issn-type":[{"value":"2151-464X","type":"print"},{"value":"2151-4658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,13]]},"assertion":[{"value":"2018-02-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-08-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}