{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T15:09:32Z","timestamp":1779289772060,"version":"3.51.4"},"reference-count":39,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2019,10,30]],"date-time":"2019-10-30T00:00:00Z","timestamp":1572393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care & Research"],"published-print":{"date-parts":[[2019,12]]},"abstract":"Objective<\/jats:title>To preliminarily explore the diagnostic potential of ultrasound (US<\/jats:styled-content>) in detecting calcium pyrophosphate (CPP<\/jats:styled-content>) crystal deposits at the hip joint in a cohort of patients with CPP<\/jats:styled-content> deposition disease (CPPD<\/jats:styled-content>) who were previously evaluated by conventional radiography (CR<\/jats:styled-content>) and to assess the sensitivity and specificity as well as the agreement between US<\/jats:styled-content> and CR<\/jats:styled-content> in the evaluation of hip CPP<\/jats:styled-content> crystal deposits.<\/jats:p><\/jats:sec>Methods<\/jats:title>Fifty consecutive patients with definite CPPD<\/jats:styled-content> and 40 age\/sex\/body mass index\u2013matched disease control subjects who had undergone hip CR<\/jats:styled-content> within the previous 6 months were enrolled. Bilateral hip US<\/jats:styled-content> examination was carried out to assess the presence of CCP<\/jats:styled-content> crystal deposits at the acetabular labrum fibrocartilage and at the femoral head's hyaline cartilage. Two independent radiologists evaluated the presence of hip CPP<\/jats:styled-content> crystal deposits on CR<\/jats:styled-content> in both groups.<\/jats:p><\/jats:sec>Results<\/jats:title>US<\/jats:styled-content> findings indicative of CPP<\/jats:styled-content> crystal deposits were found in at least 1 hip in 45 of 50 patients with CPPD<\/jats:styled-content> (90.0%) and in 73 of 100 hips (73.0%). CPP<\/jats:styled-content> crystal deposits were more frequently found at the acetabular labrum fibrocartilage than at the femoral head's hyaline cartilage (72% and 17% of the hips in patients with CPPD<\/jats:styled-content>, respectively). US<\/jats:styled-content> and CR<\/jats:styled-content> sensitivity was 90% and 86%, whereas US<\/jats:styled-content> and CR<\/jats:styled-content> specificity was 85% and 90%, respectively. Total agreement between the US<\/jats:styled-content> and CR<\/jats:styled-content> findings was 77.8%.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Our results provide new evidence supporting US<\/jats:styled-content> as a first\u2010line, sensitive, safe, and reliable imaging technique in detecting CPP<\/jats:styled-content> crystal deposits at the hip level.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.23814","type":"journal-article","created":{"date-parts":[[2018,11,26]],"date-time":"2018-11-26T06:12:50Z","timestamp":1543212770000},"page":"1671-1677","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Hip Involvement in Patients With Calcium Pyrophosphate Deposition Disease: Potential and Limits of Musculoskeletal Ultrasound"],"prefix":"10.1002","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0867-7051","authenticated-orcid":false,"given":"Andrea","family":"Di Matteo","sequence":"first","affiliation":[{"name":"Universit\u00e0 Politecnica Delle Marche Ancona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7251-7784","authenticated-orcid":false,"given":"Emilio","family":"Filippucci","sequence":"additional","affiliation":[{"name":"Universit\u00e0 Politecnica Delle Marche Ancona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edoardo","family":"Cipolletta","sequence":"additional","affiliation":[{"name":"Universit\u00e0 Politecnica Delle Marche Ancona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Musca","sequence":"additional","affiliation":[{"name":"Dr. I. 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