{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T11:08:30Z","timestamp":1780571310053,"version":"3.54.1"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,12,10]],"date-time":"2019-12-10T00:00:00Z","timestamp":1575936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1 TR000135"],"award-info":[{"award-number":["UL1 TR000135"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp;amp; Research"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To identify longitudinal predictors of discordance between patients with rheumatoid arthritis (<jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content>) and their health care providers, where patient global assessment of disease activity is substantially higher than provider global assessment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective case\u2013control study included 102 cases with positive discordance (i.e., \u226525 mm between patient and provider global assessments) and 102 controls without discordance who were matched for age, sex, <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content> duration, and Clinical Disease Activity Index (<jats:styled-content style=\"fixed-case\">CDAI<\/jats:styled-content>) score. Data were collected at the baseline visit (date of diagnosis or earliest available visit), the index visit (participation in a previous cross\u2010sectional study), and at up to 11 additional visits before the index visit. Data included patient characteristics, disease activity measures, Disease Activity Score in 28 joints (3\u2010variable) using the C\u2010reactive protein level (<jats:styled-content style=\"fixed-case\">DAS<\/jats:styled-content>28\u2010<jats:styled-content style=\"fixed-case\">CRP<\/jats:styled-content>), and medications. Data were analyzed by using linear and logistic regression models with smoothing splines for nonlinear trends.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, the mean age was 63 years, 75% of patients were female, and the mean <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content> duration was 10 years. Compared with controls, cases had higher rates of discordant visits during the 4 years before the index visit, and they had a higher <jats:styled-content style=\"fixed-case\">CDAI<\/jats:styled-content> score and <jats:styled-content style=\"fixed-case\">DAS<\/jats:styled-content>28\u2010<jats:styled-content style=\"fixed-case\">CRP<\/jats:styled-content> earlier in the disease course. Cases more frequently had antinuclear antibodies, nonerosive disease, prior depression, or prior use of antidepressants or fibromyalgia medications. Disease\u2010modifying medication use was not different between cases and controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The findings inform new hypotheses about the relationships of disease activity and antinuclear antibodies to the later occurrence of positive discordance among patients with <jats:styled-content style=\"fixed-case\">RA<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.23819","type":"journal-article","created":{"date-parts":[[2018,11,30]],"date-time":"2018-11-30T20:59:11Z","timestamp":1543611551000},"page":"18-26","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Longitudinal Occurrence and Predictors of Patient\u2010Provider Discordance Between Global Assessments of Disease Activity in Rheumatoid Arthritis: A Case\u2013Control Study"],"prefix":"10.1002","volume":"72","author":[{"given":"Divya N. V.","family":"Challa","sequence":"first","affiliation":[{"name":"Mayo Clinic  Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoran","family":"Kvrgic","sequence":"additional","affiliation":[{"name":"Mayo Clinic  Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia S.","family":"Crowson","sequence":"additional","affiliation":[{"name":"Mayo Clinic  Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric L.","family":"Matteson","sequence":"additional","affiliation":[{"name":"Mayo Clinic  Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas G.","family":"Mason","sequence":"additional","affiliation":[{"name":"Mayo Clinic  Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Clement J.","family":"Michet","sequence":"additional","affiliation":[{"name":"Mayo Clinic  Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel E.","family":"Schaffer","sequence":"additional","affiliation":[{"name":"Mayo Clinic  Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerry A.","family":"Wright","sequence":"additional","affiliation":[{"name":"Mayo Clinic  Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"John M.","family":"Davis","sequence":"additional","affiliation":[{"name":"Mayo Clinic  Rochester Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22237"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20132"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20685"},{"key":"e_1_2_6_5_1","first-page":"1293","article-title":"Sources of discrepancy in patient and physician global assessments of rheumatoid arthritis disease activity","volume":"31","author":"Nicolau G","year":"2004","journal-title":"J Rheumatol"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22902"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2015-207524"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.39480"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-016-1004-3"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2017-000551"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.34543"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.131468"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.3109\/03009742.2013.869831"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-017-1419-5"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.23103"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.27584"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.20549"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2009.10.006"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2006.054205"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780380107"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/08870446.2012.701628"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.37801"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-017-1243-y"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.3109\/14397595.2016.1153567"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612820666140825124152"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2015-208001"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kep458"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.22719"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kes285"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keu324"}],"container-title":["Arthritis Care &amp; 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