{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T23:22:31Z","timestamp":1788218551217,"version":"build-2803163510"},"reference-count":41,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T00:00:00Z","timestamp":1586304000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1049085"],"award-info":[{"award-number":["1049085"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2020,5]]},"abstract":"\n Objective<\/jats:title>\n \n The present study was undertaken to assess the comparative responsiveness of outcome measures used for the assessment of pain and function in individuals with osteoarthritis (\n OA<\/jats:styled-content>\n ) of the first metatarsophalangeal (\n MTP<\/jats:styled-content>\n ) joint.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Eighty\u2010eight patients (mean \u00b1\n SD<\/jats:styled-content>\n age 57.2 \u00b1 10.2 years) with\n OA<\/jats:styled-content>\n of the first\n MTP<\/jats:styled-content>\n joint who participated in a randomized trial completed the Foot Health Status Questionnaire (\n FHSQ<\/jats:styled-content>\n ), the Foot Function Index Revised Short Form (\n FFI<\/jats:styled-content>\n \u2010\n RS<\/jats:styled-content>\n ), and 100\u2010mm visual analog scales (\n VAS<\/jats:styled-content>\n ) of pain and stiffness at baseline and 12 weeks. Responsiveness of the subscales for each outcome measure was determined using paired\n t<\/jats:italic>\n \u2010tests, Cohen's\n d<\/jats:italic>\n coefficient, the standardized response mean (\n SRM<\/jats:styled-content>\n ), and the Guyatt index (\n GI<\/jats:styled-content>\n ). Sample size estimations were calculated based on minimal important differences (\n MID<\/jats:styled-content>\n s).\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n All outcome measures were sensitive to change and demonstrated at least medium effect sizes. Three outcome measures exhibited large or very large effect sizes for Cohen's\n d<\/jats:italic>\n coefficient, the\n SRM<\/jats:styled-content>\n , and the\n GI<\/jats:styled-content>\n : the\n FHSQ<\/jats:styled-content>\n pain subscale (\n d<\/jats:italic>\n = 1.03;\n SRM<\/jats:styled-content>\n 1.10,\n GI<\/jats:styled-content>\n score 1.30), the\n FFI<\/jats:styled-content>\n \u2010\n RS<\/jats:styled-content>\n pain subscale (\n d<\/jats:italic>\n = 1.09;\n SRM<\/jats:styled-content>\n 1.05,\n GI<\/jats:styled-content>\n score 1.73), and the 100\u2010mm\n VAS<\/jats:styled-content>\n of pain severity while walking (\n d<\/jats:italic>\n = 1.22;\n SRM<\/jats:styled-content>\n 1.07,\n GI<\/jats:styled-content>\n score 1.78). Sample size calculations indicated that between 20 and 33 participants per group would be required to detect\n MID<\/jats:styled-content>\n s using these measures.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n The\n FHSQ<\/jats:styled-content>\n pain subscale,\n FFI<\/jats:styled-content>\n \u2010\n RS<\/jats:styled-content>\n pain subscale, and the 100\u2010mm\n VAS<\/jats:styled-content>\n of pain severity while walking are the most responsive outcome measures for the assessment of pain and function in individuals with\n OA<\/jats:styled-content>\n of the first\n MTP<\/jats:styled-content>\n joint. These findings provide useful information to guide researchers in selecting appropriate outcome measures for use in future clinical trials.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/acr.23883","type":"journal-article","created":{"date-parts":[[2019,3,25]],"date-time":"2019-03-25T14:35:44Z","timestamp":1553524544000},"page":"679-684","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Comparative Responsiveness of Outcome Measures for the Assessment of Pain and Function in Osteoarthritis of the First Metatarsophalangeal Joint"],"prefix":"10.1002","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2045-3846","authenticated-orcid":false,"given":"Hylton B.","family":"Menz","sequence":"first","affiliation":[{"name":"La Trobe University, Melbourne, Victoria, Australia, and Arthritis Research UK Primary Care Centre Keele University Staffordshire 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