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Demographic information consisted of age, sex, and race (white and African American), and clinical characteristics consisted of body mass index (BMI<\/jats:styled-content>), low back pain and injury, and knee, hip, and hand OA<\/jats:styled-content>. Participants were categorized as having spine OA<\/jats:styled-content>, facet joint OA<\/jats:styled-content>, both spine OA<\/jats:styled-content> and facet joint OA<\/jats:styled-content>, or neither spine OA<\/jats:styled-content> nor facet joint OA<\/jats:styled-content> (referent group). Multinomial regression models were used to determine odds ratios (OR<\/jats:styled-content>s) and 95% confidence intervals (95% CI<\/jats:styled-content>s).<\/jats:p><\/jats:sec>Results<\/jats:title>Of 1,793 participants, the mean \u00b1 SD<\/jats:styled-content> age was 66.2 \u00b1 10.1 years, and the mean \u00b1 SD BMI<\/jats:styled-content> was 30.7 \u00b1 6.2. The majority of the participants were women (n = 1,144 [63.8%]), and 31.8% of the participants (n = 570) were African American. Eighteen percent of participants had neither spine OA<\/jats:styled-content> nor facet joint OA<\/jats:styled-content>, 22.8% had facet joint OA<\/jats:styled-content>, 13.2% had spine OA<\/jats:styled-content>, and 46.0% had both spine OA<\/jats:styled-content> and facet joint OA<\/jats:styled-content>. In adjusted analyses, African Americans were less likely to have facet joint OA<\/jats:styled-content> (OR<\/jats:styled-content> 0.68 [95% CI<\/jats:styled-content> 0.49\u20130.95]) or both spine OA<\/jats:styled-content> and facet joint OA<\/jats:styled-content> (OR<\/jats:styled-content> 0.51 [95% CI<\/jats:styled-content> 0.37\u20130.70]). Women were more likely to have facet joint OA<\/jats:styled-content> (OR<\/jats:styled-content> 1.71 [95% CI<\/jats:styled-content> 1.24\u20132.36]). Having a BMI<\/jats:styled-content> of \u226530 was associated with having facet joint OA<\/jats:styled-content> (OR<\/jats:styled-content> 1.76 [95% CI<\/jats:styled-content> 1.28\u20132.42]) and both spine OA<\/jats:styled-content> and facet joint OA<\/jats:styled-content> (OR<\/jats:styled-content> 1.85 [95% CI<\/jats:styled-content> 1.37\u20132.51]). Knee OA<\/jats:styled-content> was associated with all 3 OA<\/jats:styled-content> groups, while lower back injury was associated only with those with spine OA<\/jats:styled-content>. Participants with hip OA<\/jats:styled-content> were less likely to have facet joint OA<\/jats:styled-content>.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Race, sex, BMI<\/jats:styled-content>, hip OA<\/jats:styled-content>, and lower back injury may help identify different OA<\/jats:styled-content> phenotypes in the lumbar spine.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.23918","type":"journal-article","created":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T17:37:07Z","timestamp":1557164227000},"page":"974-981","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Different Phenotypes of Osteoarthritis in the Lumbar Spine Reflected by Demographic and Clinical Characteristics: The Johnston County Osteoarthritis Project"],"prefix":"10.1002","volume":"72","author":[{"given":"Adam P.","family":"Goode","sequence":"first","affiliation":[{"name":"Duke University School of Medicine and Duke University Durham North 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