{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T07:04:11Z","timestamp":1781766251615,"version":"3.54.5"},"reference-count":40,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,6,11]],"date-time":"2020-06-11T00:00:00Z","timestamp":1591833600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100005217","name":"National Center for Injury Prevention and Control","doi-asserted-by":"publisher","award":["CE14\u2010004 Award Number CE002520"],"award-info":[{"award-number":["CE14\u2010004 Award Number CE002520"]}],"id":[{"id":"10.13039\/100005217","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp;amp; Research"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Opioids and benzodiazepines are commonly used for management of osteoarthritis, despite evidence\u2010based recommendations to the contrary. This study aimed to quantify the prevalence of opioid and benzodiazepine prescribing for osteoarthritis. Additionally, we aimed to characterize risk factors for prescription drug misuse, abuse, and diversion among this population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a descriptive analysis of adult outpatient encounters with a primary diagnosis of osteoarthritis during a 1\u2010year period at a large health care system, excluding cancer and outpatient procedures. Demographic data, prescription data, and patient\u2010specific risk factors were collected. Descriptive analysis was conducted to characterize arthritis patients who received and did not receive prescription opioids.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During 1 year, our system had 31,123 outpatient encounters for osteoarthritis. Opioids and benzodiazepines were prescribed for nearly 27% of the encounters (n = 8,420). In all, 43% of the encounters involved patients age \u226565 years. Hydrocodone\u2010acetaminophen was the most common medication prescribed (34.3%). Most prescriptions were written by pain specialists (53%). A total of 35.5% of patients had a risk factor for prescription misuse, the most prevalent being early refill and a history of receiving \u22653 prescriptions in the past month.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Prescriptions for opioids and benzodiazepines continue to be written for osteoarthritis. These prescriptions may pose a risk for adverse outcomes since &gt;1 in 5 patients receiving prescriptions had a risk factor for misuse. Continued efforts to improve compliance with evidence\u2010based guidelines as well as multimodal and alternative pain management pathways are critical to help curb the use of opioids for management of osteoarthritis\u2010related pain. Level of evidence: level <jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.23933","type":"journal-article","created":{"date-parts":[[2019,5,25]],"date-time":"2019-05-25T06:49:31Z","timestamp":1558766971000},"page":"1081-1086","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Prevalence of Opioid and Benzodiazepine Prescriptions for Osteoarthritis"],"prefix":"10.1002","volume":"72","author":[{"given":"Vignesh K.","family":"Alamanda","sequence":"first","affiliation":[{"name":"Carolinas Medical Center and OrthoCarolina Hip and Knee Center  Charlotte North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghan K.","family":"Wally","sequence":"additional","affiliation":[{"name":"Carolinas Medical Center and OrthoCarolina Hip and Knee Center  Charlotte North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9203-8297","authenticated-orcid":false,"given":"Rachel B.","family":"Seymour","sequence":"additional","affiliation":[{"name":"Carolinas Medical Center and OrthoCarolina Hip and Knee Center  Charlotte North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryan D.","family":"Springer","sequence":"additional","affiliation":[{"name":"OrthoCarolina Hip and Knee Center and Atrium Health Musculoskeletal Institute, Atrium Health  Charlotte North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph R.","family":"Hsu","sequence":"additional","affiliation":[{"name":"Carolinas Medical Center and OrthoCarolina Hip and Knee Center  Charlotte North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Prescription Reporting With Immediate Medication Utilization Mapping Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.5435\/JAAOS-D-14-00163"},{"key":"e_1_2_6_3_1","unstructured":"Centers for Disease Control and Prevention.Drug overdose death data2017. 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