{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:43:44Z","timestamp":1791931424493,"version":"4.3.4"},"reference-count":46,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,7,8]],"date-time":"2020-07-08T00:00:00Z","timestamp":1594166400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["THC\u2010135234"],"award-info":[{"award-number":["THC\u2010135234"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2020,8]]},"abstract":"\n Objective<\/jats:title>\n \n To test the validity and reliability of screening instruments for depression and anxiety in rheumatoid arthritis (\n RA<\/jats:styled-content>\n ).\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Participants with\n RA<\/jats:styled-content>\n completed the Patient Health Questionnaire (\n PHQ<\/jats:styled-content>\n \u20102 or\n PHQ<\/jats:styled-content>\n \u20109), the Patient Reported Outcomes Measurement Information System depression short form 8a and anxiety short form 8a, the Hospital Anxiety and Depression Scale anxiety score (\n HADS<\/jats:styled-content>\n \u2010A) and depression score (\n HADS<\/jats:styled-content>\n \u2010D), the Overall Anxiety Severity and Impairment Scale, the Generalized Anxiety Disorder 2\u2010 and 7\u2010item scales, and the Kessler\u20106 scale. Clinical depression and anxiety disorders were confirmed using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Axis I Disorders (\n SCID<\/jats:styled-content>\n \u20101) research version. We reported sensitivity, specificity, positive predictive value, and negative predictive value using\n SCID<\/jats:styled-content>\n \u20101 diagnoses as the criterion standard. Test\u2013retest reliability was assessed with the intraclass correlation coefficient.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Of 150 participants, 11.3% had\n SCID<\/jats:styled-content>\n \u20101\u2013diagnosed depression, 7.3% had\n SCID<\/jats:styled-content>\n \u20101\u2013diagnosed generalized anxiety disorder, and 19.3% had any\n SCID<\/jats:styled-content>\n \u20101\u2013diagnosed anxiety disorder. For depression, sensitivity ranged from\n HADS<\/jats:styled-content>\n \u2010D (cut point 11; 35%) to\n PHQ<\/jats:styled-content>\n \u20102 (88%) and\n PHQ<\/jats:styled-content>\n \u20109 (87%). Specificity ranged from\n PHQ<\/jats:styled-content>\n \u20109 (77%) and\n PHQ<\/jats:styled-content>\n \u20102 (84%) to\n HADS<\/jats:styled-content>\n \u2010D (cut point 11; 94%). Positive predictive value ranged from 30% to 43%. Negative predictive value ranged from 92% to 98%. For generalized anxiety disorder, sensitivity ranged from\n HADS<\/jats:styled-content>\n \u2010A (cut point 11; 45%) to\n HADS<\/jats:styled-content>\n \u2010A (cut point 8; 91%). Specificity ranged from 81% to 89% for all measures except the\n HADS<\/jats:styled-content>\n \u2010A (cut point 8; 63%). Intraclass correlation coefficient estimates ranging from 0.69 to 0.88 confirmed good test\u2013retest reliability.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Depression screening instruments had good diagnostic performance; anxiety instruments were more variable. Identified depression and anxiety require clinical confirmation.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/acr.24011","type":"journal-article","created":{"date-parts":[[2019,6,14]],"date-time":"2019-06-14T11:11:49Z","timestamp":1560510709000},"page":"1130-1139","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":99,"title":["Validity and Reliability of Screening Measures for Depression and Anxiety Disorders in Rheumatoid Arthritis"],"prefix":"10.1002","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5547-3268","authenticated-orcid":false,"given":"Carol A.","family":"Hitchon","sequence":"first","affiliation":[{"name":"Max Rady College of Medicine University of Manitoba Winnipeg Manitoba Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixia","family":"Zhang","sequence":"additional","affiliation":[{"name":"Max Rady College of Medicine University of Manitoba Winnipeg Manitoba 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