{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T22:32:41Z","timestamp":1791844361973,"version":"4.3.4"},"reference-count":22,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,8,5]],"date-time":"2022-08-05T00:00:00Z","timestamp":1659657600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the diagnostic performance of ultrasound examination of the salivary glands (US\u2010SG) according to the 2019 Outcome Measures in Rheumatology (OMERACT) US scoring system for Sj\u00f6gren's syndrome (SS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The present work was a retrospective study based on a multicentric cohort with SS\/sicca syndrome. The American College of Rheumatology (ACR)\/European Alliance of Associations for Rheumatology (EULAR) 2016 classification criteria for SS (a score of \u22654 without ocular staining score), the American\u2010European Consensus Group (AECG) 2002 classification criteria, and clinician experts were considered as reference standards for diagnosis of SS. An OMERACT score of \u22652 according to 2 independent readers defined the diagnosis of SS based on US\u2010SG assessment. Diagnostic performances and interobserver reproducibility of US\u2010SG were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010two patients fulfilling the ACR\/EULAR 2016 criteria for SS were compared to 30 control subjects with sicca syndrome. Twenty\u2010five patients were diagnosed as having SS according to US\u2010SG evaluation, and they were more frequently observed in the SS group (52.5%) than in the control group (10.0%) (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). US\u2010SG showed an area under the curve (AUC) of 0.751 (95% confidence interval [95% CI] 0.621, 0.882) for the diagnosis of SS (ACR\/EULAR 2016 classification). The inclusion of US\u2010SG in the ACR\/EULAR 2016 classification improved sensitivity (91.5% versus 89.4%) with limited decrease of specificity (96.0% versus 100%) and with an AUC of 0.975 (95% CI 0.945, 1.00). Similar results were observed when US\u2010SG was included in the AECG 2002 classification criteria. Interobserver reproducibility of a score of \u22652 according to the 2019 OMERACT US scoring system for SS diagnosis was good (\u03ba\u00a0=\u00a00.73 [95% CI 0.64, 0.81]). Histologic lymphocyte infiltration of the minor salivary glands was associated with the OMERACT grading of US\u2010SG.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present study confirms the good specificity of the 2019 OMERACT US classification measures of US\u2010SG for the diagnosis of SS and its feasibility in daily practice.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.24631","type":"journal-article","created":{"date-parts":[[2021,5,11]],"date-time":"2021-05-11T01:33:55Z","timestamp":1620696835000},"page":"1924-1932","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Diagnostic Performances of Ultrasound Evaluation of Major Salivary Glands According to the 2019 Outcome Measures in Rheumatology Ultrasound Scoring System"],"prefix":"10.1002","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5134-8160","authenticated-orcid":false,"given":"Fran\u00e7ois","family":"Robin","sequence":"first","affiliation":[{"name":"University Hospital Center of Rennes  Rennes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010David","family":"Albert","sequence":"additional","affiliation":[{"name":"University Hospital Center of Rennes  Rennes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2081-8558","authenticated-orcid":false,"given":"Alain","family":"Lescoat","sequence":"additional","affiliation":[{"name":"University Hospital Center of Rennes and University of Rennes, CHU Rennes, INSERM, EHESP, IRSET, UMR_S 1085  F\u201035000 Rennes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Am\u00e9lie","family":"Martel","sequence":"additional","affiliation":[{"name":"University Hospital Center of Tours  Tours France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleth","family":"Perdriger","sequence":"additional","affiliation":[{"name":"University Hospital Center of Rennes  Rennes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"DeBandt","sequence":"additional","affiliation":[{"name":"University Hospital Center of Fort\u2010de\u2010France  Martinique France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Maillot","sequence":"additional","affiliation":[{"name":"University Hospital Center of Tours  Tours France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3560-128X","authenticated-orcid":false,"given":"Guillaume","family":"Coiffier","sequence":"additional","affiliation":[{"name":"University Hospital Center of Rennes, Rennes, France, and Hospital Center of Dinan  Dinan 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