{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T22:43:36Z","timestamp":1790981016827,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,2,3]],"date-time":"2023-02-03T00:00:00Z","timestamp":1675382400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["K24AR074534"],"award-info":[{"award-number":["K24AR074534"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["P30 AR070155"],"award-info":[{"award-number":["P30 AR070155"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The American College of Rheumatology's (ACR) 2020 guidelines for the management of gout recommend using a treat\u2010to\u2010target approach to lower serum urate (SU). Using the ACR's Rheumatology Informatics System for Effectiveness registry, we examined the use of a treat\u2010to\u2010target approach among gout patients receiving long\u2010term urate\u2010lowering therapy (ULT) and followed longitudinally by rheumatologists.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Included patients had one or more diagnoses for gout in 2018\u20132019 and continuous use of ULT for \u226512 months. We assessed the proportions of patients with SU monitoring and, among those tested, who achieved SU\u2009&lt;6.0 mg\/dl during the measurement year. Multilevel logistic regression adjusting for sociodemographics, comorbidities, region, and health care utilization was used to determine factors associated with SU monitoring and achievement of target SU.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 9,560 were included. The mean \u00b1 SD age was 67.2 \u00b1 12.7 years, 73.5% of patients were male, and 32.3% were non\u2010White. Fifty\u2010six percent of patients had at least 1 SU recorded during the measurement year; among patients with at least 1 SU recorded, 74% achieved the SU target. In multivariate analyses, non\u2010White patients were slightly less likely to be tested or achieve a target SU.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Among gout patients receiving long\u2010term ULT followed longitudinally by rheumatologists, more than half had a documented SU, and among those tested, three\u2010quarters achieved the recommended SU target. Routine monitoring of SU is a first step toward improving quality of care for patients with gout.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.25009","type":"journal-article","created":{"date-parts":[[2022,8,30]],"date-time":"2022-08-30T07:15:20Z","timestamp":1661843720000},"page":"1544-1552","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Monitoring and Achievement of Target Serum Urate Among Gout Patients Receiving <scp>Long\u2010Term Urate\u2010Lowering<\/scp> Therapy in the American College of Rheumatology <scp>RISE<\/scp> Registry"],"prefix":"10.1002","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7754-5581","authenticated-orcid":false,"given":"Nevin","family":"Hammam","sequence":"first","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3298-2112","authenticated-orcid":false,"given":"Jing","family":"Li","sequence":"additional","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Kay","sequence":"additional","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1867-0905","authenticated-orcid":false,"given":"Zara","family":"Izadi","sequence":"additional","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3508-4094","authenticated-orcid":false,"given":"Jinoos","family":"Yazdany","sequence":"additional","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2687-5043","authenticated-orcid":false,"given":"Gabriela","family":"Schmajuk","sequence":"additional","affiliation":[{"name":"University of California and San Francisco Veterans Affairs Medical Center  San Francisco California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,2,3]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24180"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr2.11121"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2021.04.011"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.23089"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.23500"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp1802313"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(92)90133-8"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.3810\/pgm.2014.03.2741"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.140588"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/pds.5127"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.2147\/CEOR.S139939"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-021-04960-x"},{"issue":"3","key":"e_1_2_4_14_1","first-page":"iii70","article-title":"Audit of the adherence to BSR guidelines on the management of gout (2007), in two primary care centres within the Merseyside region","volume":"51","author":"Chan M","year":"2012","journal-title":"Rheumatology (Oxford)"},{"key":"e_1_2_4_15_1","first-page":"37","article-title":"Variation in gout care in Aotearoa New Zealand: a national analysis of quality markers","volume":"127","author":"Jackson G","year":"2014","journal-title":"NZ Med J"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.092619"}],"container-title":["Arthritis Care &amp; 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