{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T00:48:05Z","timestamp":1759452485312,"version":"build-2065373602"},"reference-count":46,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,2,13]],"date-time":"2023-02-13T00:00:00Z","timestamp":1676246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Immunocompromised patients with chronic inflammatory disease (CID) may have experienced additional psychosocial burden during the COVID\u201019 pandemic due to their immunocompromised status. This study was undertaken to determine if vaccination would result in improved patient\u2010reported outcomes longitudinally among individuals with CID undergoing SARS\u2013CoV\u20102 vaccination regardless of baseline anxiety.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data are from a cohort of individuals with CID from 2 sites who underwent SARS\u2013CoV\u20102 vaccination. Participants completed 3 study visits before and after 2 messenger RNA vaccine doses in the initial vaccination series when clinical data were collected. Patient\u2010reported outcomes were measured using the Patient\u2010Reported Outcomes Measurement Information System 29\u2010item Health Profile and expressed as T scores, with 2 groups stratified by high and low baseline anxiety. Mixed\u2010effects models were used to examine longitudinal changes, adjusting for age, sex, and study site.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 72% of the cohort was female with a mean\u2009\u00b1\u2009SD age of 48.1\u2009\u00b1\u200915.5\u2009years. Overall, sleep disturbance improved following both doses of SARS\u2013CoV\u20102 vaccinations, and anxiety decreased after the second dose. Physical function scores worsened but did not meet the minimally important difference threshold. When stratifying by baseline anxiety, improvement in anxiety, fatigue, and social participation were greater in the high anxiety group. Physical function worsened slightly in both groups, and sleep disturbance improved significantly in the high anxiety group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Sleep disturbance decreased in a significant and meaningful way in patients with CID upon vaccination. In patients with higher baseline anxiety, social participation increased, and anxiety, fatigue, and sleep disturbance decreased. Overall, results suggest that SARS\u2013CoV\u20102 vaccination may improve mental health and well\u2010being, particularly among those with greater anxiety.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.25065","type":"journal-article","created":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T16:46:29Z","timestamp":1670431589000},"page":"1849-1856","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Sleep Disturbance and SARS\u2013CoV\u20102 Vaccinations in Patients With Chronic Inflammatory Disease"],"prefix":"10.1002","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6553-0959","authenticated-orcid":false,"given":"Niti","family":"Pawar","sequence":"first","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberly E.","family":"Taylor","sequence":"additional","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2693-3648","authenticated-orcid":false,"given":"Monica","family":"Yang","sequence":"additional","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3436-9784","authenticated-orcid":false,"given":"Parakkal","family":"Deepak","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine in St. Louis  St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wooseob","family":"Kim","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine in St. Louis  St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8724-3176","authenticated-orcid":false,"given":"Michael A.","family":"Paley","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine in St. Louis  St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehrdad","family":"Matloubian","sequence":"additional","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex","family":"Carvidi","sequence":"additional","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew A.","family":"Ciorba","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine in St. Louis  St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuel","family":"Demissie","sequence":"additional","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alia","family":"El\u2010Qunni","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine in St. Louis  St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Huang","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine in St. Louis  St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baylee","family":"Kinnett","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine in St. Louis  St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2823-5859","authenticated-orcid":false,"given":"Lily E.","family":"McMorrow","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine in St. Louis  St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Paez","sequence":"additional","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mackenzie","family":"Poole","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine in St. Louis  St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abigail","family":"Rose","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine in St. Louis  St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7430-0626","authenticated-orcid":false,"given":"Rebecca E.","family":"Schriefer","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine in St. Louis  St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4074-0516","authenticated-orcid":false,"given":"Alfred H. J.","family":"Kim","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine in St. Louis  St. Louis Missouri"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Nakamura","sequence":"additional","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8146-2519","authenticated-orcid":false,"given":"Patricia","family":"Katz","sequence":"additional","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6314-5336","authenticated-orcid":false,"given":"Lianne S.","family":"Gensler","sequence":"additional","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.17269\/s41997-020-00382-7"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2020.05.032"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2020-219498"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.7326\/M21-1757"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2021-220059"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-021-07377-5"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgast-2020-000581"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr2.11100"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.MLR.0000062554.74615.4C"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-204053"},{"key":"e_1_2_6_12_1","first-page":"10","article-title":"Changes in mental health during the COVID\u201019 pandemic among individuals with rheumatic disease [abstract]. Arthritis","volume":"72","author":"Katz P","year":"2020","journal-title":"Rheumatol"},{"key":"e_1_2_6_13_1","first-page":"10","article-title":"The association of general and COVID\u201019\u2010specific stress with changes in patient\u2010reported outcomes and comorbidities [abstract]. Arthritis","volume":"73","author":"Katz P","year":"2021","journal-title":"Rheumatol"},{"key":"e_1_2_6_14_1","first-page":"9","article-title":"Sleep disturbance improves with SARS\u2010COV2 vaccinations in patients with rheumatologic and chronic inflammatory diseases [abstract]. Arthritis","volume":"73","author":"Pawar N","year":"2021","journal-title":"Rheumatol"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.13052"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.13231"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.4103\/psychiatry.IndianJPsychiatry_523_20"},{"key":"e_1_2_6_18_1","article-title":"Sleep quality in the Indian adult population during the COVID\u201019 pandemic","volume":"13","author":"Banthiya S","year":"2021","journal-title":"Cureus"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.2196\/27331"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2020.586157"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleh.2021.02.006"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.13480"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.13519"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2021.113863"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2021.753964"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18084329"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2021.02.028"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0259040"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2021.665777"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.13119"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsps.2021.04.031"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.6061\/clinics\/2021\/e3501"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2020.10.045"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd-cus-2020-015"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2020.07.015"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.13471"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1080\/07420528.2020.1786107"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1177\/0748730420967768"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(21)00126-0"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.13439"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2020.585893"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1080\/07420528.2020.1756841"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/jsr.13326"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1590\/1806-9282.66.s2.143"},{"key":"e_1_2_6_45_1","article-title":"Anti\u2010COVID\u201019 measures threaten our healthy body weight: changes in sleep and external synchronizers of circadian clocks during confinement","volume":"25","author":"Baquerizo\u2010Sedano L","year":"2021","journal-title":"Clin Nutr"},{"key":"e_1_2_6_46_1","first-page":"191","article-title":"Sleep\u2010wake cycle impairment adding on the risk for COVID\u201019 severity in people with diabetes","volume":"13","author":"Barone MT","year":"2020","journal-title":"Sleep Sci"},{"key":"e_1_2_6_47_1","first-page":"9","article-title":"Immunosuppression attenuates antibody and neutralization titers in patients with chronic inflammatory disease following SARS\u2010CoV\u20102 vaccination [abstract]. Arthritis","volume":"73","author":"Paley M","year":"2021","journal-title":"Rheumatol"}],"container-title":["Arthritis Care &amp; Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr.25065","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/acr.25065","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr.25065","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T16:13:13Z","timestamp":1759421593000},"score":1,"resource":{"primary":{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/10.1002\/acr.25065"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,13]]},"references-count":46,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1002\/acr.25065"],"URL":"https:\/\/doi.org\/10.1002\/acr.25065","archive":["Portico"],"relation":{},"ISSN":["2151-464X","2151-4658"],"issn-type":[{"type":"print","value":"2151-464X"},{"type":"electronic","value":"2151-4658"}],"subject":[],"published":{"date-parts":[[2023,2,13]]},"assertion":[{"value":"2022-06-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}