{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T10:39:57Z","timestamp":1783420797435,"version":"3.54.6"},"reference-count":18,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,2,5]],"date-time":"2023-02-05T00:00:00Z","timestamp":1675555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["P60AR064166"],"award-info":[{"award-number":["P60AR064166"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The association between knee injury and knee osteoarthritis (OA) is understudied relative to its importance, particularly in younger populations. This study was undertaken to examine the association of knee injury with radiographic features of knee OA in military officers, who have a physically demanding profession and high rates of knee injury.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Participants were recruited in 2015\u20132017 from an existing program that enrolled 6,452 military officers during 2004\u20132009. Officers with a history of knee ligament or meniscal injuries (n\u00a0=\u00a0117 via medical record review) were compared to officers with no history of knee injury (n\u00a0=\u00a0143). Bilateral posteroanterior knee radiographs were obtained using a standardized fixed\u2010flexion positioning frame. All images were read for Kellgren\/Lawrence (K\/L) grade, osteophyte (OST), and joint space narrowing (JSN) scores. Data were analyzed using linear\u2010risk regression models with generalized estimating equations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Injured and noninjured participants were similar (mean age 28\u2009years, mean body mass index 25 kg\/m<jats:sup>2<\/jats:sup>, ~40% female). The mean time from first knee injury to imaging among injured participants was 9.2\u2009years. Compared with noninjured knees, greater prevalence of radiographic OA (K\/L grade\u2009\u2265\u20092), OST (grade\u2009\u2265\u20091), and JSN (grade\u2009\u2265\u20091) was observed among injured knees, with prevalence differences of +16% (95% confidence interval [95% CI] 10%, 22%), +29% (95% CI 20%, 38%), and\u2009+\u200917% (95% CI 10%, 24%), respectively. Approximately 1 in 6 officers with prior knee injury progressed to radiographic OA by age 30\u2009years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>At the midpoint of a projected 20\u2010year military career, officers with a history of traumatic knee injury have a markedly increased prevalence of knee radiographic OA compared to officers without injury.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.25072","type":"journal-article","created":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T02:20:16Z","timestamp":1671416416000},"page":"1744-1751","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Association of Traumatic Knee Injury With Radiographic Evidence of Knee Osteoarthritis in Military Officers"],"prefix":"10.1002","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1205-2759","authenticated-orcid":false,"given":"Yvonne M.","family":"Golightly","sequence":"first","affiliation":[{"name":"University of North Carolina, Chapel Hill, and University of Nebraska Medical Center  Omaha"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5337-6656","authenticated-orcid":false,"given":"Kristin Y.","family":"Shiue","sequence":"additional","affiliation":[{"name":"University of North Carolina  Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryalice","family":"Nocera","sequence":"additional","affiliation":[{"name":"University of North Carolina  Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Guermazi","sequence":"additional","affiliation":[{"name":"Boston University School of Medicine  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Cantrell","sequence":"additional","affiliation":[{"name":"University of North Carolina  Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan B.","family":"Renner","sequence":"additional","affiliation":[{"name":"University of North Carolina  Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darin A.","family":"Padua","sequence":"additional","affiliation":[{"name":"University of North Carolina  Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth L.","family":"Cameron","sequence":"additional","affiliation":[{"name":"Keller Army Hospital, West Point, New York, and Uniformed Services University  Bethesda Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven J.","family":"Svoboda","sequence":"additional","affiliation":[{"name":"Keller Army Hospital  West Point New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne M.","family":"Jordan","sequence":"additional","affiliation":[{"name":"University of North Carolina  Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2832-6144","authenticated-orcid":false,"given":"Richard F.","family":"Loeser","sequence":"additional","affiliation":[{"name":"University of North Carolina  Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia B.","family":"Kraus","sequence":"additional","affiliation":[{"name":"Duke University School of Medicine  Durham North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. Stefan","family":"Lohmander","sequence":"additional","affiliation":[{"name":"Lund University  Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony I.","family":"Beutler","sequence":"additional","affiliation":[{"name":"Uniformed Services University, Bethesda, Maryland, and Intermountain Healthcare  Salt Lake City Utah"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen W.","family":"Marshall","sequence":"additional","affiliation":[{"name":"University of North Carolina  Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,2,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.39692"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2018-099751"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.20589"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/JSA.0000000000000246"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/15438627.2012.680633"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.30498"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.4085\/1062-6050-45.5.519"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.csm.2014.06.012"},{"key":"e_1_2_6_10_1","volume-title":"A radiographic atlas of osteoarthritis","author":"Burnett SJ","year":"1994"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.16.4.494"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2017-097576"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ocarto.2021.100199"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f232"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/msc.1378"},{"key":"e_1_2_6_16_1","article-title":"Musculoskeletal injuries and United States Army readiness part I: overview of injuries and their strategic impact","volume":"185","author":"Molloy JM","year":"2020","journal-title":"Mil Med"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.4085\/1062-6050-51.5.08"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-016-4732-4"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.4085\/1062-6050-49.3.35"}],"container-title":["Arthritis Care &amp; Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr.25072","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/acr.25072","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr.25072","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T16:13:18Z","timestamp":1759421598000},"score":1,"resource":{"primary":{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/10.1002\/acr.25072"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,5]]},"references-count":18,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1002\/acr.25072"],"URL":"https:\/\/doi.org\/10.1002\/acr.25072","archive":["Portico"],"relation":{},"ISSN":["2151-464X","2151-4658"],"issn-type":[{"value":"2151-464X","type":"print"},{"value":"2151-4658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,5]]},"assertion":[{"value":"2022-06-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}