{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T22:43:30Z","timestamp":1790981010700,"version":"4.1.0"},"reference-count":29,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T00:00:00Z","timestamp":1687737600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100019746","name":"Sunnybrook Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019746","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the proportion of, and factors associated with, older adults with gout receiving a serum urate (SUA) test after starting urate\u2010lowering therapy (ULT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a population\u2010based retrospective cohort study in Ontario, Canada in patients ages \u226566\u2009years with gout, newly dispensed ULT between 2010 and 2019. We characterized patients with SUA testing within 6 and 12 months after ULT dispensation. Multilevel logistic regression clustered by ULT prescriber evaluated the factors associated with SUA monitoring within 6 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We included 44,438 patients with a mean \u00b1 SD age of 76.0 \u00b1\u20097.3\u2009years and 64.4% male. Family physicians prescribed 79.1% of all ULTs. SUA testing was lowest in 2010 (56.4% at 6 months) and rose over time to 71.3% in 2019 (<jats:italic>P<\/jats:italic> &lt;\u20090.0001). Compared with rheumatologists, family physicians (odds ratio [OR] 0.26 [95% confidence interval (95% CI) 0.23\u20130.29]), internists (OR 0.34 [95% CI 0.29\u20130.39]), nephrologists (OR 0.37 [95% CI 0.30\u20130.45]), and other specialties (OR 0.25 [95% CI 0.21\u20130.29]) were less likely to test SUA, as were male physicians (OR 0.87 [95% CI 0.83\u20130.91]). Patient factors associated with lower odds of SUA monitoring included rural residence (OR 0.81 [95% CI 0.77\u20130.86]), lower socioeconomic status (OR 0.91 [95% CI 0.85\u20130.97]), and patient comorbidities. Chronic kidney disease, hypertension, diabetes mellitus, and coprescription of colchicine\/oral corticosteroids (OR 1.31 [95% CI 1.23\u20131.40]) were correlated with increased SUA testing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>SUA testing is suboptimal among older adults with gout initiating ULT but is improving over time. ULT prescriber, patient, and prescription characteristics were correlated with SUA testing.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.25167","type":"journal-article","created":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T00:34:53Z","timestamp":1685406893000},"page":"2463-2471","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Serum Urate Monitoring Among Older Adults With Gout: Initiating <scp>Urate\u2010Lowering<\/scp> Therapy in Ontario, Canada"],"prefix":"10.1002","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0354-4794","authenticated-orcid":false,"given":"Timothy S. H.","family":"Kwok","sequence":"first","affiliation":[{"name":"University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3370-0006","authenticated-orcid":false,"given":"Bindee","family":"Kuriya","sequence":"additional","affiliation":[{"name":"University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6358-1197","authenticated-orcid":false,"given":"Gillian","family":"Hawker","sequence":"additional","affiliation":[{"name":"University of Toronto and Women's College Hospital  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Li","sequence":"additional","affiliation":[{"name":"ICES  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"Choy","sequence":"additional","affiliation":[{"name":"University of Toronto and Sunnybrook Research Institute  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7464-0460","authenticated-orcid":false,"given":"Jessica","family":"Widdifield","sequence":"additional","affiliation":[{"name":"University of Toronto, ICES, and Sunnybrook Research Institute  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,26]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2018.02.009"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.201392"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-209707"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24180"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2014.01.004"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.23500"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.080768"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.4065\/81.7.925"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1060028016679848"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9684909"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.01580210"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2007101075"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/03610910902859574"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.3697"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22406"},{"key":"e_1_2_7_17_1","first-page":"37","article-title":"Variation in gout care in Aotearoa New Zealand: a national analysis of quality markers","volume":"127","author":"Jackson G","year":"2014","journal-title":"N Z Med J"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanepe.2022.100416"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2006.055269"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kem056a"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.21772"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.7326\/M16-0570"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ket158"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.91B11.22445"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.118.004973"},{"issue":"1","key":"e_1_2_7_26_1","first-page":"S47","article-title":"Monitoring glycemic control","volume":"42","author":"Diabetes Canada Clinical Practice Guidelines Expert Committee","year":"2018","journal-title":"Can J Diabetes"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2020.02.086"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2014.10.013"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2017.06.014"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2015-208237"}],"container-title":["Arthritis Care &amp; 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