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Patient\u2010reported outcomes were collected at the first rheumatology visit during pregnancy. \u201cMedically ready\u201d for pregnancy was defined as (1) &lt;1 g of proteinuria, (2) no rheumatic teratogens at conception, and (3) continuing pregnancy\u2010compatible SLE medications after conception. \u201cPersonally ready\u201d was defined as planned pregnancy based on a London Measure of Unplanned Pregnancy score \u226510. Multivariable logistic regression models estimated the association of pregnancy readiness with each outcome of interest.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among the 111 individuals enrolled, lack of medical readiness for pregnancy was associated with significantly higher rates of active disease and worse pregnancy outcomes; however, these patients did not perceive themselves as having higher disease activity. Lack of personal readiness for pregnancy was associated with significantly higher patient\u2010perceived disease activity. Although medical readiness did not impact depressive symptoms substantially, lack of personal readiness for pregnancy was associated with much higher maternal depressive symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>To improve pregnancy outcomes among individuals with SLE, greater focus is needed on improving medical optimization before conception. For maternal mental health and quality of life, greater focus is needed on decreasing the incidence of unplanned pregnancy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acr.25430","type":"journal-article","created":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T01:33:45Z","timestamp":1725845625000},"page":"209-217","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The Impact of Pregnancy Readiness on Lupus Activity, Maternal Mental Health, and Pregnancy Outcomes"],"prefix":"10.1002","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9930-0852","authenticated-orcid":false,"given":"Ceshae C.","family":"Harding","sequence":"first","affiliation":[{"name":"Duke University School of Medicine  Durham North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3107-5545","authenticated-orcid":false,"given":"Amanda M.","family":"Eudy","sequence":"additional","affiliation":[{"name":"Duke University School of Medicine  Durham North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cathrine A.","family":"Sims","sequence":"additional","affiliation":[{"name":"Duke University School of Medicine  Durham North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2018-5044","authenticated-orcid":false,"given":"Cuoghi","family":"Edens","sequence":"additional","affiliation":[{"name":"University of Chicago Medicine  Chicago Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5049-4932","authenticated-orcid":false,"given":"Mehret","family":"Birru Talabi","sequence":"additional","affiliation":[{"name":"University of Pittsburgh School of Medicine  Pittsburgh Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8712-787X","authenticated-orcid":false,"given":"Rosalind","family":"Ramsey\u2010Goldman","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine  Chicago Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Neil","sequence":"additional","affiliation":[{"name":"Duke University School of Medicine  Durham North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8579-3470","authenticated-orcid":false,"given":"Megan E. 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