{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T01:22:00Z","timestamp":1783473720522,"version":"3.55.0"},"reference-count":50,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T00:00:00Z","timestamp":1764028800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T00:00:00Z","timestamp":1764028800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001782","name":"University of Melbourne","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001782","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013847","name":"Centre for Hip Health and Mobility","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013847","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000940","name":"Arthritis Australia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000940","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001215","name":"La Trobe University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001215","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp;amp; Research"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study explored the association between knee crepitus and the presence, and worsening, of structural osteoarthritis features and self\u2010reported outcomes in young adults following traumatic knee injury.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>One year following anterior cruciate ligament reconstruction (ACLR), 112 participants (41 female participants; median age 28 years old) self\u2010reported the presence and\/or absence of knee crepitus using an item from the Knee Injury and Osteoarthritis Outcome Score (KOOS). Patellofemoral and tibiofemoral osteoarthritis features (ie, cartilage lesions, osteophytes, and bone marrow lesions) were assessed from magnetic resonance imaging scans at one and five years after ACLR. Self\u2010reported outcomes were assessed with two KOOS subscales (pain and quality of life [QoL]) and the International Knee Documentation Committee subjective evaluation form (ie, self\u2010reported function). Poisson regression evaluated the relationship between self\u2010reported crepitus and the presence\/worsening of structural osteoarthritis features. General linear models explored the relationship between crepitus and self\u2010reported outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Self\u2010reported crepitus was associated with full\u2010thickness patellofemoral cartilage lesions one year after ACLR (prevalence ratio 2.70, 95% confidence interval [CI] 1.41\u20136.39) but not the risk of worsening structural osteoarthritis features between one and five years after ACLR. Those with crepitus reported worse pain (\u03b2 = \u22126.42, 95% CI \u221210.47 to \u22122.36), QoL (\u03b2 = \u221210.39, 95% CI \u221218.58 to \u22122.20), and function (\u03b2 = \u22125.49, 95% CI \u221210.92 to \u22120.06) one year after ACLR but greater improvement in pain and function between one and five years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Self\u2010reported knee crepitus was associated with the presence of full\u2010thickness patellofemoral cartilage defects one year after ACLR but was not associated with a greater risk of worsening structural osteoarthritis features up to five years after ACLR. One year after ACLR, those with crepitus reported worse pain, knee\u2010related QoL, and function.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acr.25637","type":"journal-article","created":{"date-parts":[[2025,8,26]],"date-time":"2025-08-26T03:20:04Z","timestamp":1756178404000},"page":"398-406","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Knee Crepitus and Osteoarthritis Features in Young Adults Following Traumatic Knee Injury"],"prefix":"10.1002","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-6481-041X","authenticated-orcid":false,"given":"Jamon L.","family":"Couch","sequence":"first","affiliation":[{"name":"La Trobe University and Australian International Olympic Committee Research Centre, Melbourne, Victoria, Australia, and Arthritis Research Canada  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6570-5429","authenticated-orcid":false,"given":"Brooke E.","family":"Patterson","sequence":"additional","affiliation":[{"name":"La Trobe University and Australian International Olympic Committee Research Centre  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kay M.","family":"Crossley","sequence":"additional","affiliation":[{"name":"La Trobe University and Australian International Olympic Committee Research Centre  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Guermazi","sequence":"additional","affiliation":[{"name":"Boston University School of Medicine  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew G.","family":"King","sequence":"additional","affiliation":[{"name":"La Trobe University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danilo","family":"De Oliveira Silva","sequence":"additional","affiliation":[{"name":"La Trobe University and Australian International Olympic Committee Research Centre  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6591-4976","authenticated-orcid":false,"given":"Jackie L.","family":"Whittaker","sequence":"additional","affiliation":[{"name":"Arthritis Research Canada and University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Girdwood","sequence":"additional","affiliation":[{"name":"La Trobe University and Australian International Olympic Committee Research Centre  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam G.","family":"Culvenor","sequence":"additional","affiliation":[{"name":"La Trobe University and Australian International Olympic Committee Research Centre  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2014.02.008"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2024-108866"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.24419"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/53A.5.M351"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ptsp.2018.06.002"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.23246"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-199811000-00003"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjpt.2018.09.009"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjpt.2018.11.001"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ptsp.2020.12.013"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar3845"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2022-105496"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546507307396"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22761"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.38881"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/15438627.2012.680633"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja17.00974"},{"issue":"4","key":"e_1_2_7_19_1","first-page":"1","article-title":"Rising rates of anterior cruciate ligament reconstruction in Australian adults: an analysis of Australian Medicare benefits schedule database","volume":"33","author":"Campbell RJ","year":"2024","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.90B4.20284"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2022-106299"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546518789685"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546514530088"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513517540"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2024.12.004"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2011.05.004"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2011.09.003"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2014.06.022"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546516631936"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001670050082"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20632"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2016.03.010"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f232"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546506288855"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.23854"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546510373876"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546515626539"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2017.08.006"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2020.11.002"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keaa643"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0094563"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2008.06.020"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546511423380"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2018-099257"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546516631936"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2018-100167"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2005.10.012"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msksp.2017.01.012"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e318219ab6c"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546514525910"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.21415"}],"container-title":["Arthritis Care &amp; Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr.25637","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/acr.25637","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr.25637","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T15:01:31Z","timestamp":1778252491000},"score":1,"resource":{"primary":{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/10.1002\/acr.25637"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,25]]},"references-count":50,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/acr.25637"],"URL":"https:\/\/doi.org\/10.1002\/acr.25637","archive":["Portico"],"relation":{},"ISSN":["2151-464X","2151-4658"],"issn-type":[{"value":"2151-464X","type":"print"},{"value":"2151-4658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,25]]},"assertion":[{"value":"2025-02-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}