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The aim of this study was to understand perceptions about asymptomatic hyperuricemia and views about urate\u2010lowering therapy in people with asymptomatic hyperuricemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Participants in a multinational study of asymptomatic hyperuricemia completed questionnaires about their perceptions of hyperuricemia, concern about hyperuricemia\u2010associated health conditions, and willingness to take urate\u2010lowering medication. All had a screening serum urate of \u22650.48 mmol\/L (8 mg\/dL) and no current or previous symptoms of gout.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, participants perceived that hyperuricemia had no or very few consequences on their life. Dietary factors were the most reported cause, whereas 37% did not know the cause. Participants reported a wide range in concern about hyperuricemia and the risk of developing gout. Concern about the risk of developing kidney disease or cardiovascular disease was also highly variable but was higher than concern about elevated serum urate (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001). Most did not think a urate\u2010lowering medication was necessary, and there was moderate concern about the long\u2010term use of urate\u2010lowering medication. Medication necessity beliefs were most strongly associated with whether participants were willing to take urate\u2010lowering medication (partial R\n                      <jats:sup>2<\/jats:sup>\n                      = 0.27,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Most participants perceived minimal consequences of asymptomatic hyperuricemia. Hyperuricemia was not well understood by participants, and biologic causes were generally underrecognized. Despite a range of concerns about hyperuricemia\u2010associated conditions, particularly kidney disease and cardiovascular disease, a urate\u2010lowering medication for asymptomatic hyperuricemia was not considered necessary, which aligns with most current management guidelines.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acr.25639","type":"journal-article","created":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T06:05:24Z","timestamp":1756533924000},"page":"417-423","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Perceptions About Asymptomatic Hyperuricemia and Views About Urate\u2010Lowering Therapy in People With Asymptomatic Hyperuricemia"],"prefix":"10.1002","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4632-4476","authenticated-orcid":false,"given":"Nicola","family":"Dalbeth","sequence":"first","affiliation":[{"name":"University of Auckland  Auckland New 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