{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:17:32Z","timestamp":1786976252854,"version":"build-2736575974"},"reference-count":15,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T00:00:00Z","timestamp":1767657600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T00:00:00Z","timestamp":1767657600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100006260","name":"Rheumatology Research Foundation","doi-asserted-by":"publisher","award":["Scientist Development Award"],"award-info":[{"award-number":["Scientist Development Award"]}],"id":[{"id":"10.13039\/100006260","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020167","name":"Gordon and Llura Gund Foundation","doi-asserted-by":"publisher","award":["Llura Gund Award"],"award-info":[{"award-number":["Llura Gund Award"]}],"id":[{"id":"10.13039\/100020167","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Rheumatoid arthritis (RA) is associated with interstitial lung disease, bronchiectasis, rheumatoid lung nodules, and lung cancer. Recent guidelines proposed criteria for lung disease screening in RA, but the prevalence of abnormal lung findings in patients with RA is unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Among all patients screened for lung cancer with low\u2010dose chest computed tomography (CT) in the Mass General Brigham health care system between 2015 and 2023, we identified patients with and without RA. We compared the prevalence of lung nodules, \u201cpositive screen\u201d (nodules requiring further imaging or biopsy), fibrotic lung changes, bronchiectasis, and lung cancer between patients with RA and comparators without RA using multivariable logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among consecutive patients screened for lung cancer with clinically indicated low\u2010dose chest CT, we identified 228 patients with RA and 14,805 comparators without RA. \u201cPositive screens\u201d were noted in 26.8% of patients with RA and 22.2% of patients without RA (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.10). Lung cancer was found in 4.8% of patients with RA and 3.6% of patients without RA (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.33). In multivariable models, RA was associated with positive screen (odds ratio [OR] 1.38, 95% confidence interval [CI] 1.02\u20131.87), fibrotic lung changes (OR 1.77, 95% CI 1.08\u20132.91), and bronchiectasis (OR 1.64, 95% CI 1.12\u20132.39).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Patients with RA had higher prevalence of positive screening, fibrotic changes, and bronchiectasis detected by low\u2010dose chest CT performed for lung cancer screening. Approximately one in four patients with RA who met US Preventive Services Task Force lung cancer screening criteria had a positive screen, whereas 1 in 20 had lung cancer. These results emphasize the importance of lung cancer screening among eligible patients with RA and may inform screening strategies for other lung abnormalities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acr.25680","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T04:20:23Z","timestamp":1761625223000},"page":"843-849","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Detection of Lung Abnormalities in Patients With Rheumatoid Arthritis Who Smoke and Who Were Screened for Lung Cancer With Low\u2010Dose Chest Computed Tomography Imaging in Routine Clinical Care: Results From a Large Multihospital System"],"prefix":"10.1002","volume":"78","author":[{"given":"Gregory C.","family":"McDermott","sequence":"first","affiliation":[{"name":"Mass General Brigham\/Brigham and Women's Hospital  Boston Massachusetts"},{"name":"Harvard Medical School  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Hammer","sequence":"additional","affiliation":[{"name":"Mass General Brigham\/Brigham and Women's Hospital  Boston Massachusetts"},{"name":"Harvard Medical School  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaosong","family":"Wang","sequence":"additional","affiliation":[{"name":"Mass General Brigham\/Brigham and Women's Hospital  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8361-0650","authenticated-orcid":false,"given":"Misti L.","family":"Paudel","sequence":"additional","affiliation":[{"name":"Mass General Brigham\/Brigham and Women's Hospital  Boston Massachusetts"},{"name":"Harvard Medical School  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7980-7194","authenticated-orcid":false,"given":"Sung Hae","family":"Chang","sequence":"additional","affiliation":[{"name":"Mass General Brigham\/Brigham and Women's Hospital  Boston Massachusetts"},{"name":"Soonchunhyang University  Cheonan Republic of South Korea"},{"name":"Seoul Metropolitan Government\u2010Seoul National University Boramae Medical Center  Seoul Republic of South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3766-9600","authenticated-orcid":false,"given":"Pierre\u2010Antoine","family":"Juge","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris Cit\u00e9, INSERM UMR 1152  F\u201075018 Paris France"},{"name":"H\u00f4pital Bichat\u2010Claude Bernard, AP\u2010HP  F\u201075018 Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianru","family":"Zhang","sequence":"additional","affiliation":[{"name":"Mass General Brigham\/Brigham and Women's Hospital  Boston Massachusetts"},{"name":"Beijing Tsinghua Changgung Hospital, School of Clinical Medicine Tsinghua University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Lorusso","sequence":"additional","affiliation":[{"name":"Mass General Brigham  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amie","family":"Samuylov","sequence":"additional","affiliation":[{"name":"Mass General Brigham  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0839-9661","authenticated-orcid":false,"given":"Kathleen M. M.","family":"Vanni","sequence":"additional","affiliation":[{"name":"Mass General Brigham\/Brigham and Women's Hospital  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alene","family":"Saavedra","sequence":"additional","affiliation":[{"name":"Mass General Brigham\/Brigham and Women's Hospital  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily N.","family":"Kowalski","sequence":"additional","affiliation":[{"name":"Mass General Brigham\/Brigham and Women's Hospital  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace","family":"Qian","sequence":"additional","affiliation":[{"name":"Mass General Brigham\/Brigham and Women's Hospital  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarina J.","family":"Bade","sequence":"additional","affiliation":[{"name":"Mass General Brigham\/Brigham and Women's Hospital  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin T.","family":"Mueller","sequence":"additional","affiliation":[{"name":"Mass General Brigham\/Brigham and Women's Hospital  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5556-4618","authenticated-orcid":false,"given":"Jeffrey A.","family":"Sparks","sequence":"additional","affiliation":[{"name":"Mass General Brigham\/Brigham and Women's Hospital  Boston Massachusetts"},{"name":"Harvard Medical School  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne","family":"Byrne","sequence":"additional","affiliation":[{"name":"Mass General Brigham\/Brigham and Women's Hospital  Boston Massachusetts"},{"name":"Harvard Medical School  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(02)00815-X"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.102962"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccm.2019.05.003"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtho.2023.10.006"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.42860"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.7326\/M13-2771"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.1117"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2023.109984"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.27584"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacr.2023.09.009"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0153024"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kead277"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2024.01.001"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtho.2023.11.011"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2022-002465"}],"container-title":["Arthritis Care &amp; 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