{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T20:11:16Z","timestamp":1790799076338,"version":"4.1.0"},"reference-count":49,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["R01 AR072040"],"award-info":[{"award-number":["R01 AR072040"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp;amp; Research"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Poor self\u2010reported sleep is common in rheumatoid arthritis (RA), but studies using objective sleep measures are rare. We report the prevalence of objectively measured sleep characteristics in individuals with RA and their association with clinical measures of RA disease activity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data were from a longitudinal study with four measurement periods at 6\u2010month intervals. Sleep data were collected by actigraphy over 7 days at each period. Primary actigraphy sleep variables were sleep efficiency (SE; time asleep\/time in bed), time awake after sleep onset (WASO), and total sleep time. At baseline, WatchPAT devices were also used for two nights to assess presence of sleep\u2010disordered breathing (SDB; primarily obstructive sleep apnea (OSA) indicated by the apnea\u2010hypopnea index [AHI]). Disease activity measures (Clinical Disease Activity Index [CDAI], Disease Activity Score [DAS] 28 joints, DAS C\u2010reactive protein [CRP], and DAS erythrocyte sedimentation rate) were completed by rheumatologists before each sleep\u2010monitoring period. Prevalence of sleep problems was estimated, and associations of sleep characteristics with RA disease activity were analyzed with regression models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 133 individuals enrolled, 116 had sufficient actigraph wear time for scoring at baseline, and 63 completed WatchPAT monitoring. More than 40% of the cohort had poor SE (&lt;85%) at all measurement periods completed. More than half with WatchPAT assessments had moderate to severe OSA (AHI \u2265 15). Lower SE and higher WASO were associated with greater disease activity across all measures. AHI was associated with CDAI and DAS\u2010CRP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Objectively measured sleep problems were frequent and associated with RA disease activity. Given high rates of sleep disorders and their significant negative health effects, greater attention to sleep disorders among individuals with RA is warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acr.25685","type":"journal-article","created":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T08:05:55Z","timestamp":1761293155000},"page":"713-722","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Objectively Measured Sleep Disorders in Rheumatoid Arthritis and Their Association With Disease Activity"],"prefix":"10.1002","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8146-2519","authenticated-orcid":false,"given":"Patricia","family":"Katz","sequence":"first","affiliation":[{"name":"University of California San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6661-019X","authenticated-orcid":false,"given":"Sarah L.","family":"Patterson","sequence":"additional","affiliation":[{"name":"University of California San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary C.","family":"Nakamura","sequence":"additional","affiliation":[{"name":"San Francisco Veterans Affairs Health Care System  San Francisco California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1302-8283","authenticated-orcid":false,"given":"Aric A.","family":"Prather","sequence":"additional","affiliation":[{"name":"University of California San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joonsuk","family":"Park","sequence":"additional","affiliation":[{"name":"University of California San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie L.","family":"Stone","sequence":"additional","affiliation":[{"name":"University of California San Francisco"},{"name":"California Pacific Medical Research Institute  San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.130430"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2017.1334095"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/13548506.2020.1764597"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.1742"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0000000000000363"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/14397595.2015.1131352"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.170460"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24999"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2025.152722"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-018-4009-1"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.2196\/32825"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41927-024-00405-7"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24888"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.25568"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2015.30.3.384"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.17241\/smr.2023.02075"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-023-00997-3"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8529(01)00005-6"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-019-01904-5"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/15412555.2019.1707789"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/s22239540"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/02640414.2017.1398891"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1249\/mss.0b013e31815a51b3"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.7230"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/15.5.461"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar1740"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.49.11.916"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24336"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.5498"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2024.05.043"},{"key":"e_1_2_6_32_1","unstructured":"Centers for Disease Control and Prevention.Sleep facts and stats. 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