{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T09:34:09Z","timestamp":1792056849364,"version":"4.4.0"},"reference-count":50,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T00:00:00Z","timestamp":1772928000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T00:00:00Z","timestamp":1772928000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Sj\u00f6gren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision\u2010making process, we developed an evidence\u2010based clinical practice guideline for the evaluation and management of PNS manifestations in patients with Sj\u00f6gren's disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A Topic Review Group, comprising experts in rheumatology, neurology, and guideline methodology, developed Patient, Intervention, Comparison, and Outcome questions and conducted a systematic review to identify the current best evidence on management of PNS manifestations of Sj\u00f6gren's disease. PubMed and Embase were searched for evidence published up to July 22, 2025. Literature screening, data extraction, and critical appraisal were performed in duplicate. Six case series, one retrospective cohort, and two prospective cohort studies lacking a comparison group met the inclusion criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We developed an aligned nomenclature of PNS terms that can be used across disciplines, 31 good practices for evaluation of suspected PNS manifestations, and 20 evidence\u2010based treatment recommendations, the latter of which were rated as conditional or strong based on the Grading of Recommendations Assessment, Development, and Evaluation methodology. Because of the scarcity of high\u2010level evidence, this guideline predominantly derives from expert opinion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This clinical practice guideline on PNS manifestations of Sj\u00f6gren's disease provides clinicians a rigorous, evidence\u2010based resource, developed through an expert consensus\u2010based process, for the assessment, diagnosis, and treatment of peripheral neuropathy in patients with Sj\u00f6gren's disease. Recommendations were rated as strong when the benefits significantly outweighed potential harms, creating a scenario in which most patients would prefer the advised action.<\/jats:p>\n                    <jats:p>\n                      <jats:boxed-text content-type=\"graphic\" position=\"anchor\">\n                        <jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/acr70004-gra-0001-m.png\">\n                          <jats:alt-text>image<\/jats:alt-text>\n                        <\/jats:graphic>\n                      <\/jats:boxed-text>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acr.70004","type":"journal-article","created":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T06:25:36Z","timestamp":1764656736000},"page":"860-874","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sj\u00f6gren's Disease"],"prefix":"10.1002","volume":"78","author":[{"given":"Anahita","family":"Deboo","sequence":"first","affiliation":[{"name":"Lewis Katz School of Medicine at Temple University  Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Fox","sequence":"additional","affiliation":[{"name":"Scripps Memorial Hospital and Research Foundation  La Jolla California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5080-597X","authenticated-orcid":false,"given":"Katherine M.","family":"Hammitt","sequence":"additional","affiliation":[{"name":"Sj\u00f6gren's Foundation  Reston Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Frantsve\u2010Hawley","sequence":"additional","affiliation":[{"name":"Sj\u00f6gren's Foundation  Reston Virginia"},{"name":"Temple University Kornberg School of Dentistry  Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0002-1907","authenticated-orcid":false,"given":"Matthew C.","family":"Baker","sequence":"additional","affiliation":[{"name":"Stanford University  Palo Alto California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stamatina","family":"Danielides","sequence":"additional","affiliation":[{"name":"Inova Health Systems  Ashburn Virginia"},{"name":"University of Virginia  Charlottesville Virginia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7431-6169","authenticated-orcid":false,"given":"Eduardo","family":"De Sousa","sequence":"additional","affiliation":[{"name":"Mercy Hospital  Moore Oklahoma"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brent P.","family":"Goodman","sequence":"additional","affiliation":[{"name":"Honor Health  Scottsdale Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1001-6044","authenticated-orcid":false,"given":"Jennifer K.","family":"King","sequence":"additional","affiliation":[{"name":"David Geffen School of Medicine Center at University of California  Los Angeles"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Mandel","sequence":"additional","affiliation":[{"name":"Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, New York Medical College  New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghaith","family":"Noaiseh","sequence":"additional","affiliation":[{"name":"University of Kansas  Kansas City"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pantelis P.","family":"Pavlakis","sequence":"additional","affiliation":[{"name":"Athens Medical Center  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Sarka","sequence":"additional","affiliation":[{"name":"Cedars\u2010Sinai Medical Center  Los Angeles California"},{"name":"California State University  Northridge"},{"name":"Memorial Care, Saddleback Medical Center  Laguna Hills California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. 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