{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T18:19:09Z","timestamp":1790965149212,"version":"4.1.0"},"reference-count":7,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2026,9]]},"abstract":"\n Objective<\/jats:title>\n The American College of Rheumatology recommends HLA\u2010B*58:01 allele testing before the initiation of allopurinol, specifically among Asian and African American\/Black patients, due to their increased risk for severe hypersensitivity reactions. However, testing rates remain low at many health care facilities. This study aimed to determine whether the introduction of a clinician\u2010facing dashboard, with or without a best practice alert (BPA), would increase HLA\u2010B*58:01 testing rates among eligible patients at two VA medical centers.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n In October 2022, we launched a clinician\u2010facing dashboard that displayed HLA\u2010B*58:01 testing results for all patients prescribed allopurinol at two VA medical centers. In January 2023, we added a synchronous BPA that appeared at one of the two medical centers whenever a provider entered a prescription for allopurinol. The BPA was presented as blue text on the medication order entry form and stated \u201cHLA\u2010B*58:01 genotyping recommended before rx for Asian or African American.\u201d Using data from the electronic health record, we compared the change in proportion of patients receiving allopurinol prescriptions who had HLA\u2010B*58:01 genotype testing done after implementation of the dashboard (\u00b1BPA) at the two VA medical centers.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n From October 2022 through December 2023, the number of Asian or African American\/Black patients who filled one or more prescriptions for allopurinol was 262 at the BPA + dashboard site and 330 at the dashboard only site. The percentage of Asian or African American\/Black patients who had HLA\u2010B*58:01 testing before or during the month allopurinol was prescribed increased from 8.8% in October 2022 to 35.5% in December 2023 at the dashboard + BPA site and from 2.1% to 4.5% at the dashboard only site (\n P<\/jats:italic>\n \u2009<\u20090.0001 for difference in difference). The cumulative percentage of prescribers whose patient(s) completed HLA\u2010B*58:01 testing increased from 11.7% to 46.8% at the dashboard + BPA site and from 6.9% to 10.8% at the dashboard only site (\n P<\/jats:italic>\n \u2009<\u20090.0001 for difference in difference).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Implementing a dashboard plus simple text BPA was associated with a greater increase in the proportion of patients who completed guideline\u2010recommend HLA\u2010B*58:01 testing compared to implementing a dashboard alone.<\/jats:p>\n \n \n \n image<\/jats:alt-text>\n <\/jats:graphic>\n <\/jats:boxed-text>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/acr.80016","type":"journal-article","created":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T07:38:41Z","timestamp":1770709121000},"page":"1265-1269","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of Implementing a Dashboard With or Without a Best Practice Alert on\n HLA<\/scp>\n \u2010B*58:01 Testing Rates Among Allopurinol Users at\n VA<\/scp>\n Medical Centers"],"prefix":"10.1002","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-9271-009X","authenticated-orcid":false,"given":"Abimbola","family":"Fadairo\u2010Azinge","sequence":"first","affiliation":[{"name":"San Francisco VA Medical Center San Francisco California"},{"name":"University of California San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2687-5043","authenticated-orcid":false,"given":"Gabriela","family":"Schmajuk","sequence":"additional","affiliation":[{"name":"San Francisco VA Medical Center San Francisco California"},{"name":"University of California San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sristi","family":"Sharma","sequence":"additional","affiliation":[{"name":"San Francisco VA Medical Center San Francisco California"},{"name":"University of California San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colleen P.","family":"Flanagan","sequence":"additional","affiliation":[{"name":"San Francisco VA Medical Center San Francisco California"},{"name":"University of California San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5948-0297","authenticated-orcid":false,"given":"Sara","family":"Faghihi\u2010Kashani","sequence":"additional","affiliation":[{"name":"San Francisco VA Medical Center San Francisco California"},{"name":"University of California San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Zhang","sequence":"additional","affiliation":[{"name":"San Francisco VA Medical Center San Francisco California"},{"name":"University of California San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5943-0078","authenticated-orcid":false,"given":"Mary A.","family":"Whooley","sequence":"additional","affiliation":[{"name":"San Francisco VA Medical Center San Francisco California"},{"name":"University of California San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,24]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.13250"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.221575"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2018.3556"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.241"},{"issue":"9","key":"e_1_2_5_6_1","article-title":"Facility variation in HLA\u2010B*58:01 Allele testing for Asian and Black patients receiving allopurinol in the Veterans Affairs Healthcare System [abstract]","volume":"75","author":"Sullivan J","year":"2023","journal-title":"Arthritis Rheumatol"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.2196\/humanfactors.9328"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12911-019-0976-8"}],"container-title":["Arthritis Care & Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr.80016","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/acr.80016","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr.80016","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:50:01Z","timestamp":1787755801000},"score":1,"resource":{"primary":{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/10.1002\/acr.80016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,24]]},"references-count":7,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/acr.80016"],"URL":"https:\/\/doi.org\/10.1002\/acr.80016","archive":["Portico"],"relation":{},"ISSN":["2151-464X","2151-4658"],"issn-type":[{"value":"2151-464X","type":"print"},{"value":"2151-4658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,24]]},"assertion":[{"value":"2025-04-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}