{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T13:09:40Z","timestamp":1780405780057,"version":"3.54.1"},"reference-count":44,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["TL1\u2010TR00187"],"award-info":[{"award-number":["TL1\u2010TR00187"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017759","name":"Childhood Arthritis and Rheumatology Research Alliance","doi-asserted-by":"publisher","award":["A144137"],"award-info":[{"award-number":["A144137"]}],"id":[{"id":"10.13039\/100017759","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008069","name":"University of California, San Francisco","doi-asserted-by":"publisher","award":["7504908"],"award-info":[{"award-number":["7504908"]}],"id":[{"id":"10.13039\/100008069","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["5T32AR079068"],"award-info":[{"award-number":["5T32AR079068"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp;amp; Research"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)\u2013associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among pediatric patients in the United States.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We used the 2016 and 2019 Kids\u2019 Inpatient Database (KID) to identify pediatric AAV hospitalizations. Severe AAV disease was defined by\n                      <jats:italic>International Classification of Diseases, Tenth Revision<\/jats:italic>\n                      codes indicating organ failure, complications, or the use of life\u2010sustaining procedures. We evaluated associations among race and ethnicity and household income quartile with severe disease, end\u2010stage renal disease (ESRD), and renal transplantation among those with ESRD using univariate and multivariable logistic regression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among the 673 unweighted AAV hospitalizations, 59% involved at least one severe disease feature. Hispanic race or ethnicity was associated with higher odds of severe disease (adjusted odds ratio [aOR] 1.61; 95% confidence interval [CI] 1.01\u20132.56) and ESRD (aOR 1.98; 95% CI 1.04\u20133.77). Among patients with ESRD, those in the lowest\u2010income quartile had significantly lower odds of renal transplantation compared with those in the highest quartile (aOR 0.18; 95% CI 0.04\u20130.71).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this national sample of hospitalized pediatric patients with AAV, Hispanic race or ethnicity was a statistically significant predictor of severe AAV disease and ESRD, and household income was inversely associated with renal transplantation among those with ESRD. These findings suggest that race and household income may contribute to health inequities in pediatric AAV.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acr.80088","type":"journal-article","created":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T10:38:22Z","timestamp":1779100702000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody\u2013Associated Vasculitis Hospitalized in the United States"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0172-4157","authenticated-orcid":false,"given":"Roberto Alejandro","family":"Valdovinos","sequence":"first","affiliation":[{"name":"Division of Pediatric Rheumatology, Department of Pediatrics University of California  San Francisco"},{"name":"Division of Pediatric Rheumatology, Department of Pediatrics Children's Hospital of Los Angeles  Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1873-3520","authenticated-orcid":false,"suffix":"III","given":"William Daniel","family":"Soulsby","sequence":"additional","affiliation":[{"name":"Division of Pediatric Rheumatology, Department of Pediatrics University of California  San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"von Scheven","sequence":"additional","affiliation":[{"name":"Division of Pediatric Rheumatology, Department of Pediatrics University of California  San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,2]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"World Health Organization.Social determinants of health. Accessed May 22 2025.https:\/\/www.who.int\/health-topics\/social-determinants-of-health"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/00333549141291S206"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2023.5718"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.25388"},{"key":"e_1_2_6_6_1","article-title":"Beyond health care: the role of social determinants in promoting health and health equity","author":"Artiga S","year":"2018","journal-title":"National Library of Medicine"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.37715"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-020-0204-y"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-024-07082-4"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.08060719"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-021-05916-z"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keaa769"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12969-023-00853-4"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfad028"},{"key":"e_1_2_6_15_1","unstructured":"Agency for Healthcare Research and Quality.HCUP\u2010US KID overview. Accessed March 27 2025.https:\/\/hcup-us.ahrq.gov\/kidoverview.jsp"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina56030103"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-021-05880-8"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-021-00977-1"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.097758"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-014-2617-z"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/RHU.0000000000001827"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xgen.2022.100155"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12939-016-0331-y"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2020.00785"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acap.2021.09.011"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2023.113485"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2020.09.005"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2023.101894"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.34067\/KID.0000000802"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0308407"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/jamia\/ocae178"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31829853eb"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2014530"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2025.02.001"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2018.1440205"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-021-05341-z"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.12659\/AOT.943433"},{"key":"e_1_2_6_38_1","first-page":"2021","article-title":"Census illuminates racial and ethnic composition of the country","volume":"12","author":"Jones N","year":"2020","journal-title":"United States Census Bureau. Published August"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1186\/1546-0096-12-18"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfv011"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2022.05.013"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2024-004315"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-019-0851-8"},{"key":"e_1_2_6_44_1","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/978-3-319-49379-4_18","volume-title":"Glomerulonephritis","author":"Gibson K","year":"2019"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.40134"}],"container-title":["Arthritis Care &amp; Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr.80088","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/acr.80088","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr.80088","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T12:24:32Z","timestamp":1780403072000},"score":1,"resource":{"primary":{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/10.1002\/acr.80088"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,2]]},"references-count":44,"alternative-id":["10.1002\/acr.80088"],"URL":"https:\/\/doi.org\/10.1002\/acr.80088","archive":["Portico"],"relation":{},"ISSN":["2151-464X","2151-4658"],"issn-type":[{"value":"2151-464X","type":"print"},{"value":"2151-4658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,2]]},"assertion":[{"value":"2025-07-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"acr.80088"}}