{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T10:46:59Z","timestamp":1792147619884,"version":"4.4.0"},"reference-count":28,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:00:00Z","timestamp":1792108800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:00:00Z","timestamp":1792108800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100006260","name":"Rheumatology Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006260","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30 CA016672"],"award-info":[{"award-number":["P30 CA016672"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp;amp; Research"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The objective of this study was to determine survival outcomes in older adults with axial spondyloarthritis (axSpA) and concomitant cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We conducted a population\u2010based study using Medicare claims data linked to Surveillance, Epidemiology, and End Results data to determine overall survival (OS) and cancer\u2010specific survival (CSS) in patients aged \u226566 years with in situ, localized, regional, or distant breast cancer (BC), prostate cancer (PCa), lung cancer (LC), or colorectal cancer (CRC), with and without axSpA, diagnosed January 2006 to December 2019, using\n                      <jats:italic>International Classification of Diseases for Oncology, 3rd Edition<\/jats:italic>\n                      (ICD\u2010O\u20103) site and histology codes. Patients with axSpA were matched to two to five controls without axSpA using cancer type, age at cancer diagnosis, sex, stage, and year of cancer diagnosis. We censored OS and CSS at five years and estimated rates using Kaplan\u2010Meier analyses with log\u2010rank tests. Stratified Cox proportional hazard regression models were performed for each cancer type, with CSS analyzed under the competing risks framework.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We included 6,095 patients (2,061 BC, 1,988 PCa, 1,229 LC, 817 CRC) with axSpA and 30,386 controls. Mean ages ranged from 74 (BC, PCa, LC) to 77 (CRC) years. No statistically significant differences in OS or CSS rates were observed between patients with BC, PCa, or LC and axSpA compared to controls. Patients with CRC and axSpA had higher five\u2010year OS (adjusted hazard ratio [aHR] 0.78, 95% confidence interval [CI] 0.67\u20130.91,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.002) and CSS (aHR 0.76, 95% CI 0.59\u20130.99,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.04) compared to controls.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Older patients with axSpA and BC, PCa, or LC had similar OS and CSS compared to controls. Among patients with CRC, axSpA was associated with higher OS and CSS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acr.80178","type":"journal-article","created":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T05:01:27Z","timestamp":1791262887000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Survival Outcomes in Older Adults With Axial Spondyloarthritis and Concomitant Cancer"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3333-1080","authenticated-orcid":false,"given":"Savannah","family":"Bowman","sequence":"first","affiliation":[{"name":"The University of Texas Health Science Center at Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Li","sequence":"additional","affiliation":[{"name":"The University of Texas Health Science Center at Houston School of Public Health"},{"name":"The University of Texas MD Anderson Cancer Center  Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiudong","family":"Lei","sequence":"additional","affiliation":[{"name":"The University of Texas MD Anderson Cancer Center  Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Zhao","sequence":"additional","affiliation":[{"name":"The University of Texas MD Anderson Cancer Center  Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan I.","family":"Ruiz","sequence":"additional","affiliation":[{"name":"Medical Clinic Department Hospital Alem\u00e1n  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon H.","family":"Giordano","sequence":"additional","affiliation":[{"name":"The University of Texas MD Anderson Cancer Center  Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4639-0775","authenticated-orcid":false,"given":"Alexis R.","family":"Ogdie","sequence":"additional","affiliation":[{"name":"Perelman School of Medicine University of Pennsylvania  Philadelphia"},{"name":"Center for Clinical Epidemiology and Biostatistics University of Pennsylvania  Philadelphia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5381-5797","authenticated-orcid":false,"given":"Maria E.","family":"Suarez\u2010Almazor","sequence":"additional","affiliation":[{"name":"The University of Texas MD Anderson Cancer Center  Houston"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2024.20917"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2020.04.001"},{"key":"e_1_2_6_4_1","unstructured":"Cancer Facts & the War on Cancer.SEER. 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