{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T11:54:44Z","timestamp":1792065284179,"version":"4.4.0"},"reference-count":34,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["K12TR005104"],"award-info":[{"award-number":["K12TR005104"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["K24AR080840"],"award-info":[{"award-number":["K24AR080840"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["P30AR072579"],"award-info":[{"award-number":["P30AR072579"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["R01AR064850"],"award-info":[{"award-number":["R01AR064850"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp;amp; Research"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study examined the association between positive affect and physical function in individuals with early rheumatoid arthritis (RA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed baseline data from 129 adults with early RA (persistent joint symptoms for \u226424 months) and active disease enrolled in the Central Pain in RA 2 (CPIRA\u20102) study. Patient\u2010reported outcome measures assessed positive affect (using the positive affect subscale of the Positive and Negative Affect Schedule), physical function, pain intensity, and other psychological factors. We constructed linear regression models to estimate unadjusted and adjusted cross\u2010sectional associations between positive affect and physical function. Adjusted models controlled for age, sex, body mass index, swollen joint count, symptom duration, pain intensity, and depression. Further analyses were conducted to evaluate whether pain intensity modified the relationship between positive affect and physical function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Greater self\u2010reported positive affect (\u03b2 for every five\u2010unit increase\u00a0=\u00a01.4,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.002) was associated with better physical function independent of pain intensity and depressive symptoms. In additional analyses, pain intensity significantly modified this relationship (interaction \u03b2\u00a0=\u00a0\u22120.5,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.001), and the positive association between positive affect and physical function weakened as pain intensity increased. Findings remained consistent when controlling for alternative negative affect measures (pain catastrophizing and anxiety) in place of depression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Positive affect was independently associated with self\u2010reported physical function in early RA, suggesting that resilience\u2010related psychological processes may contribute to functional outcomes during the early stages of disease. Interventions targeting positive emotional well\u2010being may complement RA treatment approaches aimed at preserving and improving physical function.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acr.80182","type":"journal-article","created":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T04:49:33Z","timestamp":1791262173000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Positive Affect Is Associated With Better Physical Function in Early Rheumatoid Arthritis"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0046-5452","authenticated-orcid":false,"given":"Burcu","family":"Aydemir","sequence":"first","affiliation":[{"name":"Northwestern University Feinberg School of Medicine  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8881-9664","authenticated-orcid":false,"given":"Jing","family":"Song","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutfiyya N.","family":"Muhammad","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy","family":"Marder","sequence":"additional","affiliation":[{"name":"University of Michigan Medical School  Ann Arbor Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2211-4861","authenticated-orcid":false,"given":"Kevin","family":"Deane","sequence":"additional","affiliation":[{"name":"University of Colorado  Denver Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4752-5029","authenticated-orcid":false,"given":"Clifton","family":"Bingham","sequence":"additional","affiliation":[{"name":"Johns Hopkins School of Medicine  Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6085-8664","authenticated-orcid":false,"given":"Lisa A.","family":"Mandl","sequence":"additional","affiliation":[{"name":"Hospital for Special Surgery Weill Cornell Medicine  New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Edwards","sequence":"additional","affiliation":[{"name":"Brigham and Women's Hospital  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith T.","family":"Moskowitz","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2105-3393","authenticated-orcid":false,"given":"Yvonne C.","family":"Lee","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine  Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-015-0777-0"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0280846"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keac137"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2005.044677"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kew243"},{"issue":"5","key":"e_1_2_6_7_1","first-page":"790","article-title":"Prevalence and correlates of depressive symptoms among 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