{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T06:56:24Z","timestamp":1791356184651,"version":"4.3.1"},"reference-count":0,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Arthritis Care &amp; Research"],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study estimated the incidence and prevalence of symptomatic hand osteoarthritis (OA) in the Dutch population using a validated algorithm that integrates free\u2010text data from primary care electronic health records (EHRs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cohort study used the Integrated Primary Care Information (IPCI) database, including EHRs from approximately 1.8 million Dutch patients aged \u226530 years between 2013 and 2023. As the International Classification of Primary Care 1 (ICPC\u20101) lacks a specific code for hand OA, cases were identified using an algorithm combining ICPC\u20101 codes for hand or wrist complaints and general OA with hand\u2010 and OA\u2010related keywords from free\u2010text notes. The algorithm was iteratively refined and validated through manual record review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Manual review of 100 algorithm\u2010identified records yielded a positive predictive value of 90%. Between 2013 and 2023, 152,900 unique patients with symptomatic hand OA were identified (mean age 68.4 years; 72% female). The age\u2010 and sex\u2010standardized prevalence increased by 65% from 5.7% in 2013 to 9.4% in 2023, while incidence rose by 20% from 7.1 to 8.5 per 1,000 person\u2010years. Both measures were consistently higher in women than in men, although the relative increase over time was greater in men.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The prevalence and incidence of symptomatic hand OA increased substantially over the past decade in the Netherlands, with the highest absolute burden among women and older adults. These trends underline the rising burden of hand OA and call for greater recognition in healthcare policy, emphasizing the need for targeted management strategies and appropriate allocation of healthcare resources.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acr.80183","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T06:46:17Z","timestamp":1791355577000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Estimating the prevalence and incidence of symptomatic hand OA in the Netherlands using primary care electronic health records."],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8744-1148","authenticated-orcid":false,"given":"Onur","family":"Kaya","sequence":"first","affiliation":[{"name":"Department of General Practice, Erasmus MC University Medical Center Rotterdam  The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9206-5431","authenticated-orcid":false,"given":"Jacoline","family":"van den Driest","sequence":"additional","affiliation":[{"name":"Department of General Practice, Erasmus MC University Medical Center Rotterdam  The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Struik","sequence":"additional","affiliation":[{"name":"Department of General Practice, Erasmus MC University Medical Center Rotterdam  The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9294-2307","authenticated-orcid":false,"given":"Margreet","family":"Kloppenburg","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Leiden University Medical Center  Leiden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruud","family":"Selles","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Erasmus MC University Medical Center Rotterdam  The Netherlands"},{"name":"Department of Rehabilitation Medicine, Erasmus MC University Medical Center Rotterdam  The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel Prieto","family":"Alhambra","sequence":"additional","affiliation":[{"name":"Department of Medical Informatics, Erasmus MC University Medical Center Rotterdam  The Netherlands"},{"name":"Nuffield Department of Orthopedics, Rheumatology, and Musculoskeletal Sciences (NDORMS) University of Oxford"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sita","family":"Bierma\u2010Zeinstra","sequence":"additional","affiliation":[{"name":"Department of General Practice, Erasmus MC University Medical Center Rotterdam  The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dieuwke","family":"Schiphof","sequence":"additional","affiliation":[{"name":"Department of General Practice, Erasmus MC University Medical Center Rotterdam  The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,6]]},"container-title":["Arthritis Care &amp; Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr.80183","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr.80183","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T06:46:18Z","timestamp":1791355578000},"score":1,"resource":{"primary":{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/10.1002\/acr.80183"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,6]]},"references-count":0,"alternative-id":["10.1002\/acr.80183"],"URL":"https:\/\/doi.org\/10.1002\/acr.80183","archive":["Portico"],"relation":{},"ISSN":["2151-464X","2151-4658"],"issn-type":[{"value":"2151-464X","type":"print"},{"value":"2151-4658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,6]]},"assertion":[{"value":"2026-04-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"acr.80183"}}