{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T16:41:11Z","timestamp":1760546471850,"version":"build-2065373602"},"reference-count":43,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,1,20]],"date-time":"2022-01-20T00:00:00Z","timestamp":1642636800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008582","name":"McGill University","doi-asserted-by":"publisher","award":["Clinical Research Support \u2010 20191218"],"award-info":[{"award-number":["Clinical Research Support \u2010 20191218"]}],"id":[{"id":"10.13039\/100008582","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ACR Open Rheumatology"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Patients with rheumatic disease (RD) have an increased risk of influenza and its complications. Despite inactivated influenza vaccine (IIV) recommendations, IIV uptake in patients with RD is suboptimal, a problem of increasing importance in the COVID\u201019 era. We estimated the frequency of IIV hesitancy and associated factors among Canadian patients with RD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional vaccine hesitancy survey was completed by rheumatology clinic patients (November 2019 to January 2020). Patients rated their likelihood of receiving the influenza vaccine (scale of 0\u201010). We categorized these as follows: likely to refuse (scale of 0\u20102), uncertain (scale of 3\u20107), or likely to accept (scale of 8\u201010). Multivariate logistical regression was used to evaluate factors associated with vaccine hesitancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 282 patients (63.5% of those approached) completed the survey, with 165 (58.5%) being likely to accept, 67 (23.8%) being likely to refuse, and 50 (17.7%) uncertain. Uncertain patients were younger and more likely to be employed than those in the other two groups. No previous influenza vaccination (odds ratio [OR] 36.6, 95% confidence interval [CI] 5.3\u2010252.9), belief that vaccination should not be mandatory (OR 0.1, 95% CI 0.0\u20100.7), unwillingness to take time off work to be vaccinated (OR 6.8, 95% CI 1.5\u201030.6), and distrust in pharmaceutical companies (OR 41.0, 95% CI 5.6\u2010301.5) predicted likeliness to refuse. Reluctance to pay for vaccination (OR 2.8, 95% CI 1.1\u20107.5) and no previous influenza vaccination (OR 18.9, 95% CI 3.3\u2010109.7) predicted uncertainty.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>More than 40% of rheumatology patients are either likely to refuse or uncertain about receiving IIV. This contributes to suboptimal vaccine coverage in this population. Interventions addressing these concerns are needed, particularly in the COVID\u201019 era.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr2.11408","type":"journal-article","created":{"date-parts":[[2022,1,20]],"date-time":"2022-01-20T06:44:10Z","timestamp":1642661050000},"page":"352-362","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Influenza Vaccine Hesitancy and Its Determinants Among Rheumatology Patients"],"prefix":"10.1002","volume":"4","author":[{"given":"Valeria","family":"Valerio","sequence":"first","affiliation":[{"name":"The Research Institute of the McGill University Health Centre  Montreal, Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Hudson","sequence":"additional","affiliation":[{"name":"Lady Davis Institute, Jewish General Hospital  Montreal, Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mianbo","family":"Wang","sequence":"additional","affiliation":[{"name":"Lady Davis Institute  Montreal, Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9515-2802","authenticated-orcid":false,"given":"Sasha","family":"Bernatsky","sequence":"additional","affiliation":[{"name":"The Research Institute of the McGill University Health Centre and McGill University  Montreal, Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth M.","family":"Hazel","sequence":"additional","affiliation":[{"name":"McGill University  Montreal, Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Ward","sequence":"additional","affiliation":[{"name":"The Research Institute of the McGill University Health Centre and McGill University  Montreal, Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8091-8334","authenticated-orcid":false,"given":"In\u00e9s","family":"Colmegna","sequence":"additional","affiliation":[{"name":"The Research Institute of the McGill University Health Centre and McGill University  Montreal, Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,1,20]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Statistics Canada. 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