{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T07:18:08Z","timestamp":1790839088811,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,6,13]],"date-time":"2022-06-13T00:00:00Z","timestamp":1655078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ACR Open Rheumatology"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The incidence rate of giant cell arteritis (GCA) is poorly studied in France. Therefore, we conducted a national hospital database study to assess the overall and regional incidence rates of GCA in France, including overseas territories.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Through the national hospitalization database of all patients hospitalized in France, new incidental GCA was identified using <jats:italic>International Classification of Diseases, 10th Revision<\/jats:italic> medical codes (M31.5\u00a0=\u00a0GCA; M31.6\u00a0=\u00a0GCA and polymyalgia rheumatica [PMR]) during 2013\u20102019. The regional incidences were analyzed by graphical methods and Poisson regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 16,540 new GCA with or without PMR diagnoses were identified in all French hospitals over 7\u2009years. The female\/male ratio was 1.8. The crude annual incidence rate of GCA with or without PMR was 9.64 (9.50\u20109.79) per 100,000 persons aged 50\u2009years or older in continental France and 2.91 (2.35\u20103.47) in overseas areas. The GCA with or without PMR incidence rate regularly increased with age in both sexes but with a later peak in men (85 vs 80\u2009years in women). The crude incidence rate was 11.43 (11.21\u201011.65) in women and 7.50 (7.31\u20107.70) in men. An east\u2013western gradient was noted with an increasing standardized incident rate (SIR) from east to west (<jats:italic>P<\/jats:italic>\u2009&lt;\u200910<jats:sup>\u22123<\/jats:sup>) using a departmental stratification of incident rates. Of note, all SIRs in continental regions were higher than those in overseas areas.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This French nationwide study provides new and dynamic insights regarding GCA with or without PMR incident rates at the country and regional levels. Important rate differences were observed between continental France and the overseas areas.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr2.11472","type":"journal-article","created":{"date-parts":[[2022,6,13]],"date-time":"2022-06-13T10:07:38Z","timestamp":1655114858000},"page":"753-759","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["<scp>Whole\u2010Country<\/scp> and Regional Incidences of Giant Cell Arteritis in French Continental and Overseas Territories: A <scp>7\u2010Year<\/scp> Nationwide Database Analysis"],"prefix":"10.1002","volume":"4","author":[{"given":"Lydia","family":"Guittet","sequence":"first","affiliation":[{"name":"Caen Universisty Hospital  Caen France"},{"name":"University of Caen  Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9083-8365","authenticated-orcid":false,"given":"Hubert","family":"de Boysson","sequence":"additional","affiliation":[{"name":"Caen Universisty Hospital  Caen France"},{"name":"University of Caen  Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damiano","family":"Cerasuolo","sequence":"additional","affiliation":[{"name":"Caen Universisty Hospital  Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00e9my","family":"Morello","sequence":"additional","affiliation":[{"name":"Caen Universisty Hospital  Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey","family":"Sultan","sequence":"additional","affiliation":[{"name":"Caen Universisty Hospital  Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Deshayes","sequence":"additional","affiliation":[{"name":"Caen Universisty Hospital  Caen France"},{"name":"University of Caen  Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Achille","family":"Aouba","sequence":"additional","affiliation":[{"name":"Caen Universisty Hospital  Caen France"},{"name":"University of Caen  Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61077-6"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.23577"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-021-02450-w"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.11195"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2009.177220"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780261007"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2006.108845"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780310515"},{"key":"e_1_2_6_10_1","first-page":"94","article-title":"Distribution of HLA\u2010DRB1 alleles of patients with polymyalgia rheumatica and giant cell arteritis in a Mediterranean population","volume":"25","author":"Combe B","year":"1998","journal-title":"J Rheumatol"},{"key":"e_1_2_6_11_1","first-page":"2148","article-title":"Mannose\u2010binding lectin variant alleles and HLA\u2010DR4 alleles are associated with giant cell arteritis","volume":"29","author":"Jacobsen S","year":"2002","journal-title":"J Rheumatol"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2003.12.001"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.57.6.380"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-121-7-199410010-00003"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0248-8663(82)80003-9"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kez251"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2017-212649"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2017-000612"},{"issue":"89","key":"e_1_2_6_19_1","article-title":"Is temporal artery biopsy essential in all cases of suspected giant cell arteritis? 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