{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T02:33:57Z","timestamp":1767926037737,"version":"3.49.0"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,10,28]],"date-time":"2024-10-28T00:00:00Z","timestamp":1730073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000098","name":"Clinical Center","doi-asserted-by":"publisher","award":["5P30AR076316"],"award-info":[{"award-number":["5P30AR076316"]}],"id":[{"id":"10.13039\/100000098","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000098","name":"Clinical Center","doi-asserted-by":"publisher","award":["P30 AR070549"],"award-info":[{"award-number":["P30 AR070549"]}],"id":[{"id":"10.13039\/100000098","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ACR Open Rheumatology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>We compared the measurement properties of a traditional physician global assessment of disease activity (PhGA) 10\u2010cm visual analog scale (PhGA<jats:sub>0\u201310<\/jats:sub>) with that of the three\u2010point numeric scale (PhGA<jats:sub>0\u20133<\/jats:sub>) in childhood\u2010onset systemic lupus erythematosus (cSLE) as part of the childhood Lupus Low Disease Activity State (cLLDAS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We used a secondary data analysis from a convenience sample of 100 patients with cSLE followed every three months for up to seven visits. Ratings of PhGA<jats:sub>0\u201310<\/jats:sub>, PhGA<jats:sub>0\u20133<\/jats:sub>, parent assessment of patient well\u2010being (ParGA) (range: 0= very poorly, 10 = very well), disease activity as measured by the SLE disease activity index 2000 (SLEDAI\u20102k), Safety of Estrogens in Lupus Erythematosus National Assessment (SELENA) SLEDAI, and the British Isles International Lupus Activity Group index (BILAG; A = 9, B = 3, C = 1, D\/E = 0) were compared. After linear transformation of PhGA<jats:sub>0\u201310<\/jats:sub> to a 0 to 3 range (tPhGA<jats:sub>0\u201310<\/jats:sub>), the frequency of PhGA<jats:sub>0\u20133<\/jats:sub> \u22641 was assessed to estimate the impact of scale type on the scoring of the cLLDAS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 600 visits, the median (range) scores of PhGA<jats:sub>0\u201310<\/jats:sub>, PhGA<jats:sub>0\u20133<\/jats:sub>, SLEDAI\u20102k, SELENA\u2010SLEDAI, and BILAG were 2 (0\u201310), 1(0\u20133), 4 (0\u201328), 4 (0\u201332), and 2 (0\u201328), respectively. PhGA<jats:sub>0\u201310<\/jats:sub> and PhGA<jats:sub>0\u20133<\/jats:sub> ratings were strong to moderately correlated with (r = 0.73; <jats:italic>P<\/jats:italic> &lt; 0.0001) and with more variability for PhGA<jats:sub>0\u20133<\/jats:sub> \u22652. SELENA\u2010SLEDAI and SLEDAI\u20102k scores were moderately correlated with PhGA<jats:sub>0\u201310<\/jats:sub> (r = 0.56\/0.54; <jats:italic>P<\/jats:italic> &lt; 0.0001). ParGA values were weakly correlated with all other measures considered (all r = \u22120.19 to \u22120.34). There were 490 of 600 visits with PhGA<jats:sub>0\u22123<\/jats:sub> \u22641 and 497 of 600 visits with tPhGA<jats:sub>0\u221210<\/jats:sub> \u22641 (\u03ba (SE) =0.59 (0.04), McNemar <jats:italic>P<\/jats:italic> = 0.4).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>PhGA<jats:sub>0\u20133<\/jats:sub> and PhGA<jats:sub>0\u201310<\/jats:sub> have comparable measurement properties and yield almost identical cLLDAS rates when used in cSLE.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr2.11737","type":"journal-article","created":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T00:40:02Z","timestamp":1730162402000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Implementation of the Lupus Low Disease Activity State in Pediatric Rheumatology Care: The Role of the Visual Analog Scale"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2126-1587","authenticated-orcid":false,"given":"Ekemini A.","family":"Ogbu","sequence":"first","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio, and Johns Hopkins University  Baltimore Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1424-7621","authenticated-orcid":false,"given":"Anna Carmela P.","family":"Sagcal\u2010Gironella","sequence":"additional","affiliation":[{"name":"Hackensack Meridian School of Medicine  Nutley New Jersey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. Anne","family":"Eberhard","sequence":"additional","affiliation":[{"name":"Cohen Children's Medical Center  Northwell, New Hyde Park New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer M.","family":"Huggins","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine  Cincinnati Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7118-3439","authenticated-orcid":false,"given":"Marisa S.","family":"Klein\u2010Gitelman","sequence":"additional","affiliation":[{"name":"Ann &amp; Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine  Chicago Illinois"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Onel","sequence":"additional","affiliation":[{"name":"Hospital for Special Surgery, Weill Cornell Medicine  New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Chen","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center  Cincinnati Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9724-675X","authenticated-orcid":false,"given":"Bin","family":"Huang","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center  Cincinnati Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9478-2987","authenticated-orcid":false,"given":"Hermine I.","family":"Brunner","sequence":"additional","affiliation":[{"name":"Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine  Cincinnati Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,10,28]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2009.12.012"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard-2022-223328"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2015-207726"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keab915"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/lupus-2022-000884"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2023.109296"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2010.132068"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20103"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.23834"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.22002"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa051135"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780400928"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keg382"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/0961203309346505"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20507"}],"container-title":["ACR Open Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr2.11737","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T15:25:35Z","timestamp":1759418735000},"score":1,"resource":{"primary":{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/10.1002\/acr2.11737"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,28]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1002\/acr2.11737"],"URL":"https:\/\/doi.org\/10.1002\/acr2.11737","archive":["Portico"],"relation":{},"ISSN":["2578-5745","2578-5745"],"issn-type":[{"value":"2578-5745","type":"print"},{"value":"2578-5745","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,28]]},"assertion":[{"value":"2024-04-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e11737"}}