{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T02:45:09Z","timestamp":1790649909406,"version":"4.1.0"},"reference-count":5,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T00:00:00Z","timestamp":1737676800000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ACR Open Rheumatology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>Dermatomyositis is an idiopathic inflammatory myopathy which can present with distinctive skin features. Despite the many treatment modalities for the treatment of dermatomyositis some patients remain refractory to treatment. We present a case of a 38\u2010year\u2010old man with recalcitrant dermatomyositis who was successfully treated with the interferon \u03b1 receptor 1\u2010inhibiting monoclonal antibody anifrolumab. Many studies have shown a correlation between dermatomyositis disease activity and the type 1 interferon pathway activity. We believe anifrolumab may be a promising option for severe cutaneous dermatomyositis.<\/jats:p>","DOI":"10.1002\/acr2.11792","type":"journal-article","created":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T10:59:28Z","timestamp":1737716368000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Recalcitrant Dermatomyositis Treated With Anifrolumab"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-6184-6511","authenticated-orcid":false,"given":"Shivang","family":"Chaudhary","sequence":"first","affiliation":[{"name":"Saint Louis University School of Medicine  St. Louis Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghan","family":"Baumer","sequence":"additional","affiliation":[{"name":"Saint Louis University School of Medicine  St. Louis Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Upton","sequence":"additional","affiliation":[{"name":"Saint Louis University School of Medicine  St. Louis Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Ong","sequence":"additional","affiliation":[{"name":"Saint Louis University School of Medicine  St. Louis Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristin","family":"Smith","sequence":"additional","affiliation":[{"name":"Saint Louis University School of Medicine  St. Louis Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"West","sequence":"additional","affiliation":[{"name":"Saint Louis University School of Medicine  St. Louis Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Kilian","sequence":"additional","affiliation":[{"name":"Saint Louis University School of Medicine  St. Louis Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,24]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.06.1309"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/14397595.2018.1467257"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.2022-0827"},{"issue":"5","key":"e_1_2_5_5_1","article-title":"Role of anifrolumab in refractory cutaneous manifestations of lupus erythematosus: a case series and literature review","volume":"15","author":"Khan MA","year":"2023","journal-title":"Cureus"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2023.10.023"}],"container-title":["ACR Open Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr2.11792","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T15:25:32Z","timestamp":1759418732000},"score":1,"resource":{"primary":{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/10.1002\/acr2.11792"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1002\/acr2.11792"],"URL":"https:\/\/doi.org\/10.1002\/acr2.11792","archive":["Portico"],"relation":{},"ISSN":["2578-5745","2578-5745"],"issn-type":[{"value":"2578-5745","type":"print"},{"value":"2578-5745","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-12-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e11792"}}