{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:02:53Z","timestamp":1787068973742,"version":"build-2736575974"},"reference-count":49,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T00:00:00Z","timestamp":1756771200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["1U01DP006698."],"award-info":[{"award-number":["1U01DP006698."]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01AG061179"],"award-info":[{"award-number":["R01AG061179"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ACR Open Rheumatology"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Systemic lupus erythematosus (SLE) is thought to accelerate the aging process. However, there is limited research on geriatric syndromes, such as falls, in this potentially vulnerable population. This study aimed to describe the prevalence of and contributors to falls in the SLE population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Participants were recruited from an ongoing population\u2010based cohort of individuals with validated SLE. Falls (number of falls and fall\u2010related injuries requiring medical attention over the past year) and perceived contributing factors were self\u2010reported. Descriptive statistics were calculated, and age\u2010, sex\u2010, and race\u2010adjusted odds ratios (aORs) of participant characteristics with falls were estimated using multivariable logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Nearly one\u2010third (30.7%) of participants (overall N = 447; 40.9% aged \u226550 years, 91.7% female, and 82.6% Black) reported falling in the past year; 19.2% fell twice or more. Loss of balance (78.1% of falls), slipping\/tripping (64.2%), and weakness (53.3%) were the most commonly reported contributing factors. Age and sex were not associated with falls, but higher physical performance (aOR, 0.78; 95% confidence interval [CI], 0.71\u20130.87) was associated with lower odds of falls. Higher SLE activity (aOR, 1.78; 95% CI, 1.44\u20132.21) and damage (aOR, 1.22; 95% CI, 1.00\u20131.49), greater depressive symptoms (aOR, 1.43; 95% CI, 1.14,1\u201380), and taking fall risk\u2010increasing drugs (antidepressants: aOR, 1.82; 95% CI, 1.13\u20132.93; pain medications: aOR, 2.60; 95% CI, 1.68\u20134.00; opioids: aOR, 4.52; 95% CI, 2.39\u20138.56) were associated with higher odds of falls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Falls were common in our cohort, regardless of age. Our results suggest potential interventions for reducing falls, like better control of SLE, physical therapy, depression screening, and medication review.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acr2.70098","type":"journal-article","created":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T04:51:32Z","timestamp":1756875092000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Falls Among Individuals With Systemic Lupus Erythematosus: An Observational Study"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3805-3290","authenticated-orcid":false,"given":"Chelsea R.","family":"Perfect","sequence":"first","affiliation":[{"name":"Duke University School of Medicine and Durham Veterans Affairs Geriatric Research Education and Clinical Center, Durham VA Medical Center  Durham North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Barrett","family":"Bowling","sequence":"additional","affiliation":[{"name":"Duke University School of Medicine and Durham Veterans Affairs Geriatric Research Education and Clinical Center, Durham VA Medical Center  Durham North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2361-0787","authenticated-orcid":false,"given":"S. Sam","family":"Lim","sequence":"additional","affiliation":[{"name":"Emory University  Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charmayne","family":"Dunlop\u2010Thomas","sequence":"additional","affiliation":[{"name":"Emory University  Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Courtney","family":"Hoge","sequence":"additional","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3508-4094","authenticated-orcid":false,"given":"Jinoos","family":"Yazdany","sequence":"additional","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8146-2519","authenticated-orcid":false,"given":"Patricia P.","family":"Katz","sequence":"additional","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0809-8981","authenticated-orcid":false,"given":"Laura C.","family":"Plantinga","sequence":"additional","affiliation":[{"name":"University of California  San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,2]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2022-222276"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.41632"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0961203320984845"},{"key":"e_1_2_7_5_1","volume-title":"StatPearls","author":"Justiz Vaillant AA","year":"2024"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2007.01156.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.2174\/1874609808666150727111904"},{"key":"e_1_2_7_8_1","volume-title":"Presented at: 55th Annual Primary Care Review","author":"Byerly LK","year":"2024"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/lupus-2016-000186"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.181338"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr2.11722"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2024.02.020"},{"key":"e_1_2_7_13_1","volume-title":"The Second Fifty Years: Promoting Health and Preventing Disability","author":"Berg R","year":"1992"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2013.04.003"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2020.07.002"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780400928"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr2.11588"},{"key":"e_1_2_7_18_1","volume-title":"Risk Factors for Falls","author":"Centers for Disease Control and Prevention","year":"2017"},{"key":"e_1_2_7_19_1","unstructured":"The falls management program: a quality improvement initiative for nursing facilities.Agency for Healthcare Research and Quality website.https:\/\/www.ahrq.gov\/patient-safety\/settings\/long-term-care\/resource\/injuries\/fallspx\/slides.html#51008."},{"key":"e_1_2_7_20_1","unstructured":"Cognition.NIH Toobox.http:\/\/www.healthmeasures.net\/explore-measurement-systems\/nih-toolbox\/intro-to-nih-toolbox\/cognition."},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.2165\/00019053-199304050-00006"},{"issue":"11","key":"e_1_2_7_22_1","first-page":"S337","article-title":"Measures of work disability and productivity: Rheumatoid Arthritis Specific Work Productivity Survey (WPS\u2010RA), Workplace Activity Limitations Scale (WALS), Work Instability Scale for Rheumatoid Arthritis (RA\u2010WIS), Work Limitations Questionnaire (WLQ), and Work Productivity and Activity Impairment Questionnaire (WPAI)","volume":"63","author":"Tang K","year":"2011","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ket300"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1191\/0961203303lu332oa"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20503"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22231"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5868-8-115"},{"key":"e_1_2_7_28_1","unstructured":"Score the IPAQ.IQAQ website.https:\/\/sites.google.com\/view\/ipaq\/score"},{"issue":"1","key":"e_1_2_7_29_1","first-page":"141","article-title":"Psychometric properties and performance of the Patient Reported Outcomes Measurement Information System\u00ae (PROMIS\u00ae) Depression Short Forms in ethnically diverse groups","volume":"58","author":"Teresi JA","year":"2016","journal-title":"Psychol Test Assess Model"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24011"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.2307\/2136404"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/gps.4049"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/geront\/10.1_Part_1.20"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/geront\/9.3_Part_1.179"},{"key":"e_1_2_7_35_1","unstructured":"Intro to PROMIS.HealthMeasures.http:\/\/www.healthmeasures.net\/explore-measurement-systems\/promis\/intro-to-promis"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/geronj\/49.2.M85"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.25266"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2009.357"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7235a1"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2023.8154"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.1044744"},{"key":"e_1_2_7_42_1","volume-title":"StatPearls [Internet]","author":"Appeadu MK","year":"2025"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494813483215"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2022.102911"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24756"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.5606\/ArchRheumatol.2017.6079"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2023.3329"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s41999-021-00498-0"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.14979"},{"key":"e_1_2_7_50_1","unstructured":"Older adult falls data.Centers for Disease Control and Prevention website.https:\/\/www.cdc.gov\/falls\/data-research\/"}],"container-title":["ACR Open Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr2.70098","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T08:18:00Z","timestamp":1759479480000},"score":1,"resource":{"primary":{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/10.1002\/acr2.70098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":49,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1002\/acr2.70098"],"URL":"https:\/\/doi.org\/10.1002\/acr2.70098","archive":["Portico"],"relation":{},"ISSN":["2578-5745","2578-5745"],"issn-type":[{"value":"2578-5745","type":"print"},{"value":"2578-5745","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"2024-10-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70098"}}