{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T02:07:49Z","timestamp":1779934069189,"version":"3.53.1"},"reference-count":5,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ACR Open Rheumatology"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:p>Juvenile idiopathic arthritis is a rare but severe childhood\u2010onset arthritis that carries a high risk of structural joint damage. We report the case of a 32\u2010year\u2010old man with a history of juvenile idiopathic arthritis who underwent bilateral hip arthroplasty at age 23 and bilateral ankle arthroplasty at age 24. His subsequent orthopedic course was complex, involving a left ankle prosthetic infection, spacer implantation, and eventual reimplantation of the prosthesis. Despite these interventions, he developed persistent left ankle pain, swelling, and warmth, consistent with residual synovitis. The patient was treated with adalimumab and had no evidence of active arthritis at other sites. Non\u2010steroidal anti\u2010inflammatory drugs, sural nerve neuromodulation, and intra\u2010articular glucocorticoid injections failed to provide adequate relief. Selective transarterial embolization of the malleolar branch of the anterior tibial artery was therefore performed, resulting in marked improvement in pain and swelling. In conclusion, transarterial embolization proved feasible and led to meaningful short\u2010term clinical benefit, supporting its potential as an adjunctive therapeutic option in carefully selected cases of residual refractory ankle arthritis.<\/jats:p>","DOI":"10.1002\/acr2.70141","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T13:05:18Z","timestamp":1764248718000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Transarterial Embolization for Refractory Ankle Synovitis in an Adult Patient With a History of Juvenile Idiopathic Arthritis"],"prefix":"10.1002","volume":"7","author":[{"given":"Francesco","family":"Ursini","sequence":"first","affiliation":[{"name":"Medicine and Rheumatology Unit IRCCS Istituto Ortopedico Rizzoli  Bologna Italy"},{"name":"Department of Biomedical and Neuromotor Sciences Alma Mater Studiorum University of Bologna  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacopo","family":"Ciaffi","sequence":"additional","affiliation":[{"name":"Medicine and Rheumatology Unit IRCCS Istituto Ortopedico Rizzoli  Bologna Italy"},{"name":"Department of Biomedical and Neuromotor Sciences Alma Mater Studiorum University of Bologna  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuliano","family":"Peta","sequence":"additional","affiliation":[{"name":"Diagnostic and Interventional Radiology Unit IRCCS Istituto Ortopedico Rizzoli  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesare","family":"Faldini","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences Alma Mater Studiorum University of Bologna  Bologna Italy"},{"name":"1st Orthopaedic and Traumatologic Clinic IRCCS Istituto Ortopedico Rizzoli  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giancarlo","family":"Facchini","sequence":"additional","affiliation":[{"name":"Diagnostic and Interventional Radiology Unit IRCCS Istituto Ortopedico Rizzoli  Bologna Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,27]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-021-00332-8"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2024.152525"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/03009742.2025.2547454"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keaf153"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-025-07566-x"}],"container-title":["ACR Open Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr2.70141","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T09:17:00Z","timestamp":1767345420000},"score":1,"resource":{"primary":{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/10.1002\/acr2.70141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,27]]},"references-count":5,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1002\/acr2.70141"],"URL":"https:\/\/doi.org\/10.1002\/acr2.70141","archive":["Portico"],"relation":{},"ISSN":["2578-5745","2578-5745"],"issn-type":[{"value":"2578-5745","type":"print"},{"value":"2578-5745","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,27]]},"assertion":[{"value":"2025-09-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70141"}}