{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T07:59:54Z","timestamp":1790236794160,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T00:00:00Z","timestamp":1789344000000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100006093","name":"Patient-Centered Outcomes Research Institute","doi-asserted-by":"publisher","award":["ME\u20102022C2\u201025573"],"award-info":[{"award-number":["ME\u20102022C2\u201025573"]}],"id":[{"id":"10.13039\/100006093","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acrjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ACR Open Rheumatology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Artificial intelligence (AI) is rapidly transforming clinical decision\u2010making. However, patient perspectives on these technologies remain understudied in pediatric care. We investigated patient and parent perspectives on AI use in juvenile idiopathic arthritis (JIA) care among a highly engaged cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted four focus groups with patients with JIA and parents of children with JIA to explore: (1) perceived utility of AI, (2) anticipated benefits and risks of its implementation, (3) information needs for fostering understanding and trust in AI tools, and (4) preferences for model calibration, including acceptable performance thresholds and trade\u2010offs between sensitivity and specificity. Transcripts were analyzed using reflexive thematic analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Participants included 8 patients with JIA (3 children and 5 adults) and 10 parents (n\u00a0=\u00a018 total). Participants expressed enthusiasm for AI's potential to support personalized treatment, but acceptance was universally contingent on AI serving as decision support rather than replacing physician judgment. Primary concerns were physician over\u2010reliance undermining clinical reasoning, privacy vulnerability for pediatric populations, and potential algorithmic bias. Participants emphasized that successful implementation must preserve the patient\u2013provider relationship and accommodate individual circumstances, including disease severity, patient preferences, and lifestyle factors. Acceptable sensitivity\u2013specificity trade\u2010offs varied widely, shaped by each participant's disease experience. Some participants emphasized that trust required disclosing AI use, training data sources, model performance, model provenance and conflicts of interest, and cohort characteristics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Patients expect AI technologies to augment rather than replace clinical judgment, operate transparently, and accommodate individual circumstances. These priorities should guide AI implementation to ensure trust and meaningful adoption.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acr2.90105","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T06:17:02Z","timestamp":1789453022000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Patient Perspectives and Expectations on the Use of Artificial Intelligence to Guide Treatment Decision\u2010Making in Juvenile Idiopathic Arthritis: A Qualitative Study"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1241-1013","authenticated-orcid":false,"given":"Mei\u2010Sing","family":"Ong","sequence":"first","affiliation":[{"name":"Computational Health Informatics Program Boston Children's Hospital  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1913-6472","authenticated-orcid":false,"given":"Laura E.","family":"Schanberg","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University Medical Center  Durham North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Kohlheim","sequence":"additional","affiliation":[{"name":"Independent Patient Partner  Granville Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny","family":"Leal","sequence":"additional","affiliation":[{"name":"Independent Patient Partner  Columbus Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley","family":"Luo","sequence":"additional","affiliation":[{"name":"Brown University  Providence Rhode Island"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc D.","family":"Natter","sequence":"additional","affiliation":[{"name":"Computational Health Informatics Program Boston Children's Hospital  Boston Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7132-3390","authenticated-orcid":false,"given":"Yukiko","family":"Kimura","sequence":"additional","affiliation":[{"name":"Joseph M. Sanzari Children's Hospital, Hackensack Meridian School of Medicine  Hackensack New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,14]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2014.212"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-025-01541-1"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-4642(23)00267-5"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/children7090145"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2023.10.027"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1191\/1478088706qp063oa"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/amajethics.2019.138"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2025.01.013"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0279088"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.2196\/70487"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2025.22400"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.2196\/58462"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/AIp2401167"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2025.14026"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.2196\/50853"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12911-023-02162-y"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2020.00117"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-021-00385-9"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjebm-2024-112919"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/amiajnl-2011-000089"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-025-01503-7"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/medethics-2018-105118"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/bioe.13158"}],"container-title":["ACR Open Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr2.90105","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/acr2.90105","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acr2.90105","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T07:20:52Z","timestamp":1790234452000},"score":1,"resource":{"primary":{"URL":"https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/10.1002\/acr2.90105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":23,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1002\/acr2.90105"],"URL":"https:\/\/doi.org\/10.1002\/acr2.90105","archive":["Portico"],"relation":{},"ISSN":["2578-5745","2578-5745"],"issn-type":[{"value":"2578-5745","type":"print"},{"value":"2578-5745","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"2026-03-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e90105"}}