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This study assessed the care\u2010related quality of life of parent\u2010caregivers of children with JIA using the Care\u2010Related Quality of Life instrument (CarerQol), identified the most affected caregiving dimensions, and explored associations with sociodemographic and clinical factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed baseline data from the Canada\u2010Netherlands Personalized Medicine Network in Childhood Arthritis and Rheumatic Diseases (UCAN CAN\u2010DU) study. Clinical data including symptoms, disease activity, and caregiver\u2010reported data were collected. Caregivers of children under 18 completed the CarerQol, a preference\u2010weighted caregiver quality\u2010of\u2010life instrument from which a utility score (0\u2013100, worst to better caregiving situation) can be calculated, as well as a well\u2010being visual analog scale (VAS; 0\u201310, completely unhappy to happy). Stepwise linear regression examined associations between CarerQol utility and VAS; and sociodemographic and clinical variables, with model selection based on goodness of fit.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 439 caregivers, 86% were mothers, the mean age was 41 years, and 44% of children had oligoarticular JIA. The mean CarerQol scores were utility of 81.5 (SD 10.8); VAS of 7.3 (SD 1.7). Most caregivers reported fulfillment and caregiving support. Over 40% reported problems in physical health, mental health, and combining caregiving with daily activities. Lower utilities were associated with receiving extra help, having physical health conditions, caring for children using injectable medication, and caring for male children. Higher utilities were associated with living with a partner, caring for children aged 10 to 15, and residing in the Netherlands (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Many caregivers experience substantial burden, particularly in physical and mental health, and managing caregiving alongside daily responsibilities. Child\u2010 and family\u2010related factors are key variables associated with caregiving quality of life. Results emphasize the need for tailored interventions and support systems to improve JIA caregivers\u2019 well\u2010being.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acr2.90156","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:17:48Z","timestamp":1790309868000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Impact of Caring for a Child With Juvenile Idiopathic Arthritis on Caregiver Quality of Life"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8467-8008","authenticated-orcid":false,"given":"Deborah A.","family":"Marshall","sequence":"first","affiliation":[{"name":"Department of Community Health Sciences, Cumming School of Medicine University of Calgary  Calgary Alberta Canada"},{"name":"Alberta Children's Hospital Research Institute University of Calgary  Calgary Alberta Canada"},{"name":"Department of Medicine, Cumming School of Medicine University of Calgary  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4321-9953","authenticated-orcid":false,"given":"Ana Claudia","family":"Fuhrmann","sequence":"additional","affiliation":[{"name":"Department of Community Health Sciences, Cumming School of Medicine University of Calgary  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2185-8762","authenticated-orcid":false,"given":"Rodrigo","family":"Dal Ben","sequence":"additional","affiliation":[{"name":"Department of Community Health Sciences, Cumming School of Medicine University of Calgary  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4681-9893","authenticated-orcid":false,"given":"Gillian R.","family":"Currie","sequence":"additional","affiliation":[{"name":"Department of Community Health Sciences, Cumming School of Medicine University of Calgary  Calgary Alberta Canada"},{"name":"Alberta Children's Hospital Research Institute University of Calgary  Calgary Alberta Canada"},{"name":"Department of Pediatrics, Cumming School of Medicine University of Calgary  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2361-725X","authenticated-orcid":false,"given":"Rae S. M.","family":"Yeung","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Immunology, and Medical Science The Hospital for Sick Children and University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4226-0949","authenticated-orcid":false,"given":"Sebastiaan J.","family":"Vastert","sequence":"additional","affiliation":[{"name":"Department of Pediatric Immunology and Rheumatology Wilhelmina Children's Hospital, University Medical Center Utrecht  Utrecht the Netherlands"},{"name":"Faculty of Medicine University Medical Center Utrecht  Utrecht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9548-5562","authenticated-orcid":false,"given":"Nico","family":"Wulffraat","sequence":"additional","affiliation":[{"name":"Department of Pediatric Immunology and Rheumatology Wilhelmina Children's Hospital, University Medical Center Utrecht  Utrecht the Netherlands"},{"name":"Faculty of Medicine University Medical Center Utrecht  Utrecht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2759-2822","authenticated-orcid":false,"given":"Joost F.","family":"Swart","sequence":"additional","affiliation":[{"name":"Department of Pediatric Immunology and Rheumatology Wilhelmina Children's Hospital, University Medical Center Utrecht  Utrecht the Netherlands"},{"name":"Faculty of Medicine University Medical Center Utrecht  Utrecht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5756-3638","authenticated-orcid":false,"given":"Susanne","family":"Benseler","sequence":"additional","affiliation":[{"name":"Alberta Children's Hospital Research Institute University of Calgary  Calgary Alberta Canada"},{"name":"Department of Pediatrics, Cumming School of Medicine University of Calgary  Calgary Alberta 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