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Parents\u2019 responses to the Work Productivity and Activity Impairment, Specific Health Problem related to their child's JIA were combined with demographic information and clinical reports from enrollment to 12 months. Demographic and clinical data were summarized, and generalized estimating equations (GEEs) were used to estimate absenteeism, presenteeism, work impairment, daily activities impairment, and wage loss. GEE covariates included JIA activity state, time from study enrollment, patient age group, and patient age at diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 754 parents, 635 were mothers with median age of 42 years (interquartile range\u00a0=\u00a010 years). Changes in work commitment were reported by 79 parents, primarily reducing working hours (n\u00a0=\u00a055). Over 12 months, because of their child's JIA, there was an estimated 6% of missed work time (absenteeism), 14% of working time impairment (presenteeism), 12% of combined work impairment, and 16% of daily activities impairment. Absenteeism resulted in an estimated average annual wage loss of \u20ac3,510 per family. Work impairment and activity impairment estimates were higher for parents of children with more severe disease activity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study is the first to capture the adjusted work impairment and activity impairment for a large international cohort of parents of children across all JIA subtypes and at different stages of treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acr2.90157","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:33:11Z","timestamp":1790310791000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Work Productivity Loss and Activity Impairment in Parents of Children With Juvenile Idiopathic Arthritis"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8467-8008","authenticated-orcid":false,"given":"Deborah A.","family":"Marshall","sequence":"first","affiliation":[{"name":"Department of Community Health Sciences, Cumming School of Medicine University of Calgary  Calgary Alberta Canada"},{"name":"Alberta Children's Hospital Research Institute University of Calgary  Calgary Alberta Canada"},{"name":"Department of Medicine, Cumming School of Medicine University of Calgary  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2185-8762","authenticated-orcid":false,"given":"Rodrigo","family":"Dal Ben","sequence":"additional","affiliation":[{"name":"Department of Community Health Sciences, Cumming School of Medicine University of Calgary  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4681-9893","authenticated-orcid":false,"given":"Gillian R.","family":"Currie","sequence":"additional","affiliation":[{"name":"Department of Community Health Sciences, Cumming School of Medicine University of Calgary  Calgary Alberta Canada"},{"name":"Alberta Children's Hospital Research Institute University of Calgary  Calgary Alberta Canada"},{"name":"Department of Pediatrics, Cumming School of Medicine University of Calgary  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2361-725X","authenticated-orcid":false,"given":"Rae S. M.","family":"Yeung","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Immunology and Medical Science, The Hospital for Sick Children University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4226-0949","authenticated-orcid":false,"given":"Sebastiaan J.","family":"Vastert","sequence":"additional","affiliation":[{"name":"Department of Pediatric Immunology and Rheumatology Wilhelmina Children's Hospital\/UMC Utrecht  Utrecht the Netherlands"},{"name":"Faculty of Medicine University Medical Center Utrecht  Utrecht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9548-5562","authenticated-orcid":false,"given":"Nico","family":"Wulffraat","sequence":"additional","affiliation":[{"name":"Department of Pediatric Immunology and Rheumatology Wilhelmina Children's Hospital\/UMC Utrecht  Utrecht the Netherlands"},{"name":"Faculty of Medicine University Medical Center Utrecht  Utrecht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2759-2822","authenticated-orcid":false,"given":"Joost F.","family":"Swart","sequence":"additional","affiliation":[{"name":"Department of Pediatric Immunology and Rheumatology Wilhelmina Children's Hospital\/UMC Utrecht  Utrecht the Netherlands"},{"name":"Faculty of Medicine University Medical Center Utrecht  Utrecht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5756-3638","authenticated-orcid":false,"given":"Susanne","family":"Benseler","sequence":"additional","affiliation":[{"name":"Alberta Children's Hospital Research Institute University of Calgary  Calgary Alberta Canada"},{"name":"Department of Pediatrics, Cumming School of Medicine University of Calgary  Calgary Alberta Canada"},{"name":"Children's Health Ireland  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the UCAN CAN\u2010DU and UCAN CURE Consortia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1546-0096-8-20"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2007.07.006"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2007.07.007"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12969-022-00713-7"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healthpol.2014.12.016"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-015-0508-1"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12969-021-00641-y"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12969-019-0321-x"},{"issue":"5","key":"e_1_2_7_10_1","first-page":"920","article-title":"The burden of systemic juvenile idiopathic arthritis for patients and caregivers: an international survey and retrospective chart review","volume":"36","author":"Shenoi S","year":"2018","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2022.04.014"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000003545"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-020-05425-w"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/jcag\/gwad009"},{"key":"e_1_2_7_15_1","unstructured":"Margaret Reilly.Reilly Associates: WPAI general information. 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