{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T23:41:31Z","timestamp":1790725291172,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005057","name":"National Tsing Hua University","doi-asserted-by":"publisher","award":["109Q2806E1"],"award-info":[{"award-number":["109Q2806E1"]}],"id":[{"id":"10.13039\/501100005057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Adv. Biosys."],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Real\u2010time reverse transcription\u2010polymerase chain reaction (qRT\u2010PCR) using specimens collected from nasopharyngeal and\/or oropharyngeal swabs is the standard screening approach for coronavirus disease 2019 (COVID\u201019). While PCR is rapid and highly accurate, it requires costly laboratory equipment and healthcare professionals that limit its use for large\u2010scale screening of mild or asymptomatic patients. Self\u2010collection kits for use in the home could remedy this and have consequently received great attention. In April, 2020, a self\u2010collection kit from LapCorp was the first such kit to be approved by the FDA. In the following month, May 2020, another kit developed by Everlywell received FDA approval, and more kits are evidently on their way to the market in the United Kingdom and elsewhere. Because these home\u2010based, self\u2010collection kits are easy to use and may be more acceptable for patients, they provide a superior screening option for mild or asymptomatic patients under self\u2010quarantine. These kits conserve personal protective equipment and healthcare manpower already in short supply. The primary issues affecting the efficacy of this approach are the potential for inappropriate sampling and insufficient clinical examination. A detailed review of the commercially available kits currently available is provided and their prospective impact is noted during the current pandemic.<\/jats:p>","DOI":"10.1002\/adbi.202000150","type":"journal-article","created":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T05:54:23Z","timestamp":1601618063000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Home Sample Self\u2010Collection for COVID\u201019 Patients"],"prefix":"10.1002","volume":"4","author":[{"given":"Wan\u2010Ting","family":"Liao","sequence":"first","affiliation":[{"name":"Institute of Biomedical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters National Tsing Hua University  Hsinchu 30013 Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min\u2010Yen","family":"Hsu","sequence":"additional","affiliation":[{"name":"School of Medicine Chung Shan Medical University  Taichung 40201 Taiwan"},{"name":"Department of Ophthalmology Chung Shan Medical University Hospital  Taichung 40201 Taiwan"},{"name":"Biotechnology Center National Chung Hsing University  Taichung 40227 Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching\u2010Fen","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Pediatrics National Cheng Kung University Hospital College of Medicine National Cheng Kung University  Tainan 70403 Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai\u2010Feng","family":"Hung","sequence":"additional","affiliation":[{"name":"Department of Medical Research Division of Translational Research Taipei Veterans General Hospital  Taipei 11217 Taiwan"},{"name":"Department of Dentistry School of Dentistry National Yang\u2010Ming University  Taipei 11221 Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8644-1960","authenticated-orcid":false,"given":"Chao\u2010Min","family":"Cheng","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters National Tsing Hua University  Hsinchu 30013 Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10]]},"reference":[{"key":"e_1_2_9_1_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/mBio.00722-20","volume":"11","author":"Patel R.","year":"2020","journal-title":"MBio"},{"key":"e_1_2_9_2_1","unstructured":"Center for Disease Control and Prevention (CDC) Testing for COVID\u201019 https:\/\/www.cdc.gov\/coronavirus\/2019\u2010ncov\/symptoms\u2010testing\/testing.html2020."},{"key":"e_1_2_9_3_1","first-page":"1843","volume":"323","author":"Wang W.","year":"2020","journal-title":"J. Am. Med. Assoc."},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2020.04.001"},{"key":"e_1_2_9_5_1","first-page":"4","volume":"10","author":"Yang T.","year":"2020","journal-title":"Diagnostics"},{"key":"e_1_2_9_6_1","unstructured":"Center for Disease Control and Prevention (CDC) Interim Guidelines for Collecting Handling and Testing Clinical Specimens for COVID\u201019. (2020) https:\/\/www.cdc.gov\/coronavirus\/2019\u2010ncov\/lab\/guidelines\u2010clinical\u2010specimens.html."},{"key":"e_1_2_9_7_1","unstructured":"Pixel by LabCorp COVID\u201019 At\u2010Home Kits from LabCorp https:\/\/www.pixel.labcorp.com\/covid\u2010192020."},{"key":"e_1_2_9_8_1","unstructured":"Everlywell COVID\u201019 Test Home Collection Kit https:\/\/www.everlywell.com\/products\/covid\u201019\u2010test\/2020."},{"key":"e_1_2_9_9_1","unstructured":"Quest Diagnostics RC home Collection kit https:\/\/www.fda.gov\/media\/140234\/download2020."},{"key":"e_1_2_9_10_1","unstructured":"LetsGetChecked COVID\u201019 Home Collection Kit https:\/\/www.fda.gov\/media\/138406\/download2020."},{"key":"e_1_2_9_11_1","unstructured":"CRL Rapid Response COVID\u201019 Self Collection Testing Kit https:\/\/www.fda.gov\/media\/140664\/download 2020."},{"key":"e_1_2_9_12_1","unstructured":"Private Harley Street Covid\u201019 PCR test: in clinic or at home by a medical professional (current infection status) https:\/\/privateharleystreetclinic.com\/products\/covid\u201019\u2010test2020."},{"key":"e_1_2_9_13_1","unstructured":"Blue Horizon Medicals Covid\u201019 (SARS\u2010CoV\u20102) Coronavirus Home Test Kit by Dual RT\u2010PCR https:\/\/tinyurl.com\/yca6y96k2020."},{"key":"e_1_2_9_14_1","unstructured":"Center for Disease Control and Prevention (CDC) Packaging and Transporting Infectious Substances Category A Infectious Substance https:\/\/tinyurl.com\/y7ozl9hx2020."},{"key":"e_1_2_9_15_1","doi-asserted-by":"crossref","first-page":"104442","DOI":"10.1016\/j.jcv.2020.104442","volume":"128","author":"LeBlanc J. J.","year":"2020","journal-title":"J. Clin. Virol."},{"key":"e_1_2_9_16_1","first-page":"1","author":"Wehrhahna M. C.","year":"2020","journal-title":"J. Clin. Virol."},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3121\/cmr.2012.1084"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25496"},{"key":"e_1_2_9_19_1","first-page":"264","volume":"182","author":"Tu Y.\u2010P.","year":"2019","journal-title":"medRxiv"},{"key":"e_1_2_9_20_1","author":"Kojima N.","year":"2020","journal-title":"medRxiv"},{"key":"e_1_2_9_21_1","doi-asserted-by":"crossref","first-page":"2016382","DOI":"10.1001\/jamanetworkopen.2020.16382","volume":"3","author":"McCulloch D. J.","year":"2020","journal-title":"JAMA Network Open"}],"container-title":["Advanced Biosystems"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/adbi.202000150","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/adbi.202000150","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/adbi.202000150","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T10:41:53Z","timestamp":1693737713000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/adbi.202000150"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":21,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1002\/adbi.202000150"],"URL":"https:\/\/doi.org\/10.1002\/adbi.202000150","archive":["Portico"],"relation":{},"ISSN":["2366-7478","2366-7478"],"issn-type":[{"value":"2366-7478","type":"print"},{"value":"2366-7478","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10]]},"assertion":[{"value":"2020-06-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2000150"}}