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In this study, EEG signals are recorded immediately after mTBI by connecting a bipolar single lead to injured animals. And three types of EEG features, namely time domain, frequency domain, and nonlinear dynamics, are screened for optimal feature subset in mTBI detection. First, EEG signals of animals are recorded before and after establishing the animal model of mTBI. Second, signal preprocessing, feature extraction, and feature preprocessing are performed to obtain the full\u2010feature dataset, and 1442 feature subsets are obtained by 15 feature reduction algorithms extracted from combinations of 47 features. Ultimately, the support vector machines and K\u2010nearest neighbor algorithms are trained and tested respectively, and their performance is comprehensively compared to determine the optimal feature subset for mTBI detection. In the EEG dataset collected in this study, a total of eight feature subsets extracted from combinations of original 47 features and classification models with 100% accuracy are obtained. This study shows the perspective of immediately detecting mTBI based on a bipolar single\u2010lead EEG.<\/jats:p>","DOI":"10.1002\/adbi.202300208","type":"journal-article","created":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T23:23:00Z","timestamp":1693956180000},"source":"Crossref","is-referenced-by-count":1,"title":["Study of the Immediately Detection of Mild Traumatic Brain Injury by Feature Engineering on Electroencephalography"],"prefix":"10.1002","volume":"7","author":[{"given":"Lilong","family":"Zhou","sequence":"first","affiliation":[{"name":"Army Medical University  Gaotanyan Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hang","family":"Hu","sequence":"additional","affiliation":[{"name":"Army Medical University  Gaotanyan Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Ning","sequence":"additional","affiliation":[{"name":"Army Medical University  Gaotanyan Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zelin","family":"Bai","sequence":"additional","affiliation":[{"name":"Army Medical University  Gaotanyan Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia","family":"Xu","sequence":"additional","affiliation":[{"name":"Army Medical University  Gaotanyan Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Xu","sequence":"additional","affiliation":[{"name":"Army Medical University  Gaotanyan Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Zhuang","sequence":"additional","affiliation":[{"name":"Army Medical University  Gaotanyan Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Sun","sequence":"additional","affiliation":[{"name":"Army Medical University  Gaotanyan Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haisheng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Army Medical University  Gaotanyan Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Wang","sequence":"additional","affiliation":[{"name":"Army Medical University  Gaotanyan Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiheng","family":"Cui","sequence":"additional","affiliation":[{"name":"Army Medical University  Gaotanyan Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gui","family":"Jin","sequence":"additional","affiliation":[{"name":"Army Medical University  Gaotanyan Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongjian","family":"Nian","sequence":"additional","affiliation":[{"name":"Army Medical University  Gaotanyan Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kui","family":"Li","sequence":"additional","affiliation":[{"name":"Army Medical University  Gaotanyan Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aowen","family":"Duan","sequence":"additional","affiliation":[{"name":"Army Medical University  Gaotanyan Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6673-7978","authenticated-orcid":false,"given":"Mingsheng","family":"Chen","sequence":"additional","affiliation":[{"name":"Army Medical University  Gaotanyan Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,9,5]]},"reference":[{"key":"e_1_2_9_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuchi.2020.02.002"},{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30469-1"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2022.0103"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2016.84"},{"key":"e_1_2_9_5_1","volume":"12","author":"Kerry M. 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