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In addition, the role of EA in slowing myopia progression by improving retinal mitochondrial function is further investigated. scRNA\u2010seq identified ten cell clusters in the retina of LIM and EA guinea pigs and mitochondrial respiratory chain\u2010related genes in Cones and Muller\u2010glia cells\u2014Cytochrome oxidase subunit III (COX3), NADH dehydrogenase subunit 4 (ND4), and NADH dehydrogenase subunit 2 (ND2) are closely related to lens\u2010induced myopia. A comprehensive atlas in the retina of LIM and EA guinea pigs at a single\u2010cell level is established, and the positive role of EA in improving retinal mitochondrial function to slow the experimental myopia progression in guinea pigs is revealed.<\/jats:p>","DOI":"10.1002\/adbi.202400269","type":"journal-article","created":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T07:29:25Z","timestamp":1728977365000},"source":"Crossref","is-referenced-by-count":2,"title":["Electroacupuncture Slows Experimental Myopia Progression by Improving Retinal Mitochondrial Function: A Study Based on Single\u2010Cell RNA Sequencing"],"prefix":"10.1002","volume":"8","author":[{"given":"Jiawen","family":"Hao","sequence":"first","affiliation":[{"name":"Shandong University of Traditional Chinese Medicine  Jinan 250002 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunxiao","family":"Xie","sequence":"additional","affiliation":[{"name":"Shandong Provincial Key Laboratory of 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