{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:11:28Z","timestamp":1790716288527,"version":"4.1.0"},"reference-count":275,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T00:00:00Z","timestamp":1738800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T00:00:00Z","timestamp":1738800000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52293381"],"award-info":[{"award-number":["52293381"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Advanced Biology"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The increasing morbidity and mortality caused by multidrug\u2010resistant bacteria alerts human beings to the fact that conventional antibiotics are no longer reliable and effective alternatives are imperatively needed. Owing to wide range of sources, diverse structures, and unique mode of action, antimicrobial peptides have been highly anticipated and extensively studied in recent years. Besides, the integration of artificial intelligence helps researchers gain access to the vast unexplored chemical space, which opens more opportunities for the optimization and design of novel structures. Moreover, Due to advances in chemistry and synthetic biology, researchers have also begun to focus on the potential of chemical mimetics of antimicrobial peptides. In this review, a comprehensive discussion about natural and synthesized antimicrobial peptides as well as their chemical mimetics is made, so as to provide a comprehensive summary of this field and inspire follow\u2010up research.<\/jats:p>","DOI":"10.1002\/adbi.202400461","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T11:24:02Z","timestamp":1738841042000},"source":"Crossref","is-referenced-by-count":18,"title":["Antimicrobial Peptides and Their Mimetics: Promising Candidates of Next\u2010Generation Therapeutic Agents Combating Multidrug\u2010Resistant Bacteria"],"prefix":"10.1002","volume":"9","author":[{"given":"Tianyi","family":"Zhang","sequence":"first","affiliation":[{"name":"MOE Key Laboratory of Macromolecule Synthesis and Functionalization, Department of Polymer Science and Engineering Zhejiang University  Hangzhou 310058 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6584-4111","authenticated-orcid":false,"given":"Qiao","family":"Jin","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Macromolecule Synthesis and Functionalization, Department of Polymer Science and Engineering Zhejiang University  Hangzhou 310058 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Ji","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Macromolecule Synthesis and Functionalization, Department of Polymer Science and Engineering Zhejiang University  Hangzhou 310058 P. R. China"},{"name":"State Key Laboratory of Transvascular Implantation Devices, The Second Affiliated Hospital Zhejiang University School of Medicine  88 Jiefang Rd Hangzhou 310009 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,6]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.1093\/hesc\/9780198866664.001.0001"},{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.7748\/ns.25.38.49.s53"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201701400"},{"key":"e_1_2_8_4_1","first-page":"56","volume":"14","author":"Adedeji W. A.","year":"2016","journal-title":"Ann. Ib. Postgrad. Med."},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2542-5196(23)00026-8"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3439"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S173867"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c12151"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/macp.202100440"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202302578"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1863-2378.2011.01450.x"},{"key":"e_1_2_8_12_1","volume-title":"Tackling drug\u2010resistant infections globally: final report and recommendations","author":"O'Neill J.","year":"2016"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2018.12.015"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01553-x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40104-022-00796-y"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines6030063"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.201900543"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1152\/physiolgenomics.00150.2004"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-020-00443-1"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202305726"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00056-05"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222111691"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2023.116072"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2021.101229"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0CS00729C"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac933"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2008.09.013"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro1839"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1FD00039J"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tifs.2021.01.005"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/bip.20911"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.332270"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom8010004"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1021\/jo900933r"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2018.08.012"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2020.05.016"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10989-014-9419-7"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2021.119647"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/prot.340220210"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.csbj.2024.04.022"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2010.02.023"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0BM00801J"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2018.12.015"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2019.183092"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M204928200"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.02832"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics12090840"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/bip.10260"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.17.6597"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.langmuir.7b04219"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.1c03564"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2022.102718"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2014.1002424"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biotechadv.2016.05.007"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612824666180416113811"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.286.5448.2361"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M006770200"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2015.10.018"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.2174\/1574891X13666180628105928"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.00044-18"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.2174\/1568026615666150703121700"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-6737-7_1"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2016.00065"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2015.11.2237"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0090228"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1002\/psc.1319"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.5.6.951"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2008.03.020"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.12247"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1023\/B:RUBI.0000043782.21640.c2"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/414729"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1002\/psc.2990"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkl667"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1991.tb07969.x"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2006.12.005"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.1002\/chir.23607"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2014.10.009"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.3439"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi0012843"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.201000792"},{"key":"e_1_2_8_81_1","unstructured":"Y. H.Ho T. C.Sung C. S.Chen Mol. Cell. Proteomics2012 11 M111.014720."},{"key":"e_1_2_8_82_1","first-page":"1","volume":"8","author":"Zhang Q. Y.","year":"2021","journal-title":"Mil. Med. Res."},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0148514"},{"key":"e_1_2_8_84_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2011.07612.x"},{"key":"e_1_2_8_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2020.113138"},{"key":"e_1_2_8_86_1","doi-asserted-by":"publisher","DOI":"10.1080\/07388551.2020.1796576"},{"key":"e_1_2_8_87_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.03072"},{"key":"e_1_2_8_88_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2017.7267"},{"key":"e_1_2_8_89_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2012.01459.x"},{"key":"e_1_2_8_90_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2019.00233"},{"key":"e_1_2_8_91_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02518-16"},{"key":"e_1_2_8_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2014.12.001"},{"key":"e_1_2_8_93_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-019-0058-8"},{"key":"e_1_2_8_94_1","doi-asserted-by":"publisher","DOI":"10.1159\/000338648"},{"key":"e_1_2_8_95_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.01871"},{"key":"e_1_2_8_96_1","first-page":"39","volume":"6","author":"Lishko V. K.","year":"2016","journal-title":"Res. Rep. Biochem."},{"key":"e_1_2_8_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bonr.2019.100237"},{"key":"e_1_2_8_98_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0903984"},{"key":"e_1_2_8_99_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2021.751010"},{"key":"e_1_2_8_100_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.172.6.3758"},{"key":"e_1_2_8_101_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1600886"},{"key":"e_1_2_8_102_1","doi-asserted-by":"publisher","DOI":"10.1159\/000332941"},{"key":"e_1_2_8_103_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules18067058"},{"key":"e_1_2_8_104_1","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics9010024"},{"key":"e_1_2_8_105_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1001067"},{"key":"e_1_2_8_106_1","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2021.691532"},{"key":"e_1_2_8_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2006.04.006"},{"key":"e_1_2_8_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2023.106749"},{"key":"e_1_2_8_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2024.106305"},{"key":"e_1_2_8_110_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-24807-0"},{"key":"e_1_2_8_111_1","doi-asserted-by":"publisher","DOI":"10.1002\/med.21879"},{"key":"e_1_2_8_112_1","doi-asserted-by":"publisher","DOI":"10.4012\/dmj.2022-094"},{"key":"e_1_2_8_113_1","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2020.00162"},{"key":"e_1_2_8_114_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0282(2001)60:3<194::AID-BIP10031>3.0.CO;2-8"},{"key":"e_1_2_8_115_1","doi-asserted-by":"publisher","DOI":"10.1002\/bit.27222"},{"key":"e_1_2_8_116_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.00983"},{"key":"e_1_2_8_117_1","doi-asserted-by":"publisher","DOI":"10.1002\/psc.3031"},{"key":"e_1_2_8_118_1","first-page":"6523","volume":"10","author":"Scudiero O.","year":"2015","journal-title":"Int. J. Nanomed."},{"key":"e_1_2_8_119_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.8.3302-3310.2005"},{"key":"e_1_2_8_120_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.582779"},{"key":"e_1_2_8_121_1","doi-asserted-by":"publisher","DOI":"10.1038\/s12276-018-0116-z"},{"key":"e_1_2_8_122_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00249-015-1094-x"},{"key":"e_1_2_8_123_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0CS01026J"},{"key":"e_1_2_8_124_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3383"},{"key":"e_1_2_8_125_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells9041022"},{"key":"e_1_2_8_126_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-022-00712-1"},{"key":"e_1_2_8_127_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-71771-8"},{"key":"e_1_2_8_128_1","doi-asserted-by":"publisher","DOI":"10.1002\/psc.3098"},{"key":"e_1_2_8_129_1","doi-asserted-by":"publisher","DOI":"10.1002\/slct.201800855"},{"key":"e_1_2_8_130_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd3591"},{"key":"e_1_2_8_131_1","doi-asserted-by":"publisher","DOI":"10.1080\/17460441.2016.1201058"},{"key":"e_1_2_8_132_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.576272"},{"key":"e_1_2_8_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2003.11.008"},{"key":"e_1_2_8_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2008.07.023"},{"key":"e_1_2_8_135_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-2952(99)00259-2"},{"key":"e_1_2_8_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2019.105123"},{"key":"e_1_2_8_137_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-07440-0"},{"key":"e_1_2_8_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/0167-4838(93)90024-L"},{"key":"e_1_2_8_139_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0067597"},{"key":"e_1_2_8_140_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(88)80077-2"},{"key":"e_1_2_8_141_1","doi-asserted-by":"publisher","DOI":"10.1093\/abbs\/gmx091"},{"key":"e_1_2_8_142_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.17-22243"},{"key":"e_1_2_8_143_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10989-004-1719-x"},{"key":"e_1_2_8_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-440X(96)80057-1"},{"key":"e_1_2_8_145_1","doi-asserted-by":"publisher","DOI":"10.1128\/mSphere.00377-18"},{"key":"e_1_2_8_146_1","doi-asserted-by":"publisher","DOI":"10.1002\/psc.3094"},{"key":"e_1_2_8_147_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja3042004"},{"key":"e_1_2_8_148_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.9b00440"},{"key":"e_1_2_8_149_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.7b01117"},{"key":"e_1_2_8_150_1","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S166236"},{"key":"e_1_2_8_151_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2019.05.002"},{"key":"e_1_2_8_152_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11596-019-2042-2"},{"key":"e_1_2_8_153_1","doi-asserted-by":"publisher","DOI":"10.2174\/1568026620666200303122626"},{"key":"e_1_2_8_154_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2017.03.014"},{"key":"e_1_2_8_155_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2019.111814"},{"key":"e_1_2_8_156_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-58014-6"},{"key":"e_1_2_8_157_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2012.01.048"},{"key":"e_1_2_8_158_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2016.02.035"},{"key":"e_1_2_8_159_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6CP05464A"},{"key":"e_1_2_8_160_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00622-06"},{"key":"e_1_2_8_161_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1506207112"},{"key":"e_1_2_8_162_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2021.140604"},{"key":"e_1_2_8_163_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-014-1550-9"},{"key":"e_1_2_8_164_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2006.02.021"},{"key":"e_1_2_8_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2016.05.010"},{"key":"e_1_2_8_166_1","doi-asserted-by":"publisher","DOI":"10.1134\/S1068162020040044"},{"key":"e_1_2_8_167_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2003.10.041"},{"key":"e_1_2_8_168_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.regpep.2010.08.010"},{"key":"e_1_2_8_169_1","doi-asserted-by":"publisher","DOI":"10.1021\/bm201098j"},{"key":"e_1_2_8_170_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0090095"},{"key":"e_1_2_8_171_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2005.03.058"},{"key":"e_1_2_8_172_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-022-00991-2"},{"key":"e_1_2_8_173_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1TB00167A"},{"key":"e_1_2_8_174_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2023.04.022"},{"key":"e_1_2_8_175_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c03199"},{"key":"e_1_2_8_176_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1TB00429H"},{"key":"e_1_2_8_177_1","doi-asserted-by":"publisher","DOI":"10.1093\/database\/baac011"},{"key":"e_1_2_8_178_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2018.07.014"},{"key":"e_1_2_8_179_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-2285-7_4"},{"key":"e_1_2_8_180_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3PY00395G"},{"key":"e_1_2_8_181_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtbi.2017.02.012"},{"key":"e_1_2_8_182_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2013.01.019"},{"key":"e_1_2_8_183_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep42362"},{"key":"e_1_2_8_184_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-19752-w"},{"key":"e_1_2_8_185_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-021-00801-1"},{"key":"e_1_2_8_186_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05233"},{"key":"e_1_2_8_187_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M117.805499"},{"key":"e_1_2_8_188_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-022-01226-0"},{"key":"e_1_2_8_189_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2018.06.011"},{"key":"e_1_2_8_190_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2018.08.001"},{"key":"e_1_2_8_191_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.9b00915"},{"key":"e_1_2_8_192_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202305375"},{"key":"e_1_2_8_193_1","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics11070936"},{"key":"e_1_2_8_194_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0285.2010.01044.x"},{"key":"e_1_2_8_195_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-021-04156-x"},{"key":"e_1_2_8_196_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2018.01.005"},{"key":"e_1_2_8_197_1","first-page":"377","volume":"58","author":"Porto W. F.","year":"2012","journal-title":"Protein Structure"},{"key":"e_1_2_8_198_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja305644e"},{"key":"e_1_2_8_199_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph12020082"},{"key":"e_1_2_8_200_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom11030471"},{"key":"e_1_2_8_201_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-021-00689-x"},{"key":"e_1_2_8_202_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2018.12.010"},{"key":"e_1_2_8_203_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201412070"},{"key":"e_1_2_8_204_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.2c00757"},{"key":"e_1_2_8_205_1","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.201500299"},{"key":"e_1_2_8_206_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja303304j"},{"key":"e_1_2_8_207_1","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201003104"},{"key":"e_1_2_8_208_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-37573-y"},{"key":"e_1_2_8_209_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-39726-5"},{"key":"e_1_2_8_210_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph16121643"},{"key":"e_1_2_8_211_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja061186q"},{"key":"e_1_2_8_212_1","doi-asserted-by":"publisher","DOI":"10.1021\/ml300307b"},{"key":"e_1_2_8_213_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm0340039"},{"key":"e_1_2_8_214_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm049582b"},{"key":"e_1_2_8_215_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0080025"},{"key":"e_1_2_8_216_1","doi-asserted-by":"publisher","DOI":"10.1007\/12_2010_85"},{"key":"e_1_2_8_217_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2012.06.006"},{"key":"e_1_2_8_218_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi049414l"},{"key":"e_1_2_8_219_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0135961"},{"key":"e_1_2_8_220_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1309"},{"key":"e_1_2_8_221_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2006.03.009"},{"key":"e_1_2_8_222_1","doi-asserted-by":"publisher","DOI":"10.1002\/bip.23274"},{"key":"e_1_2_8_223_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200352791"},{"key":"e_1_2_8_224_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3SC06441G"},{"key":"e_1_2_8_225_1","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.1012"},{"key":"e_1_2_8_226_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.0c01026"},{"key":"e_1_2_8_227_1","doi-asserted-by":"publisher","DOI":"10.1021\/ar400066v"},{"key":"e_1_2_8_228_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja077288d"},{"key":"e_1_2_8_229_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6SC00615A"},{"key":"e_1_2_8_230_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.5b00359"},{"key":"e_1_2_8_231_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2018.07.038"},{"key":"e_1_2_8_232_1","doi-asserted-by":"publisher","DOI":"10.1002\/pola.27987"},{"key":"e_1_2_8_233_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.8b00399"},{"key":"e_1_2_8_234_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9BM01666J"},{"key":"e_1_2_8_235_1","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202117377"},{"key":"e_1_2_8_236_1","doi-asserted-by":"publisher","DOI":"10.1002\/marc.202200010"},{"key":"e_1_2_8_237_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.200801523"},{"key":"e_1_2_8_238_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja801662y"},{"key":"e_1_2_8_239_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.200900049"},{"key":"e_1_2_8_240_1","doi-asserted-by":"publisher","DOI":"10.1021\/jp1083357"},{"key":"e_1_2_8_241_1","doi-asserted-by":"publisher","DOI":"10.1002\/pola.10325"},{"key":"e_1_2_8_242_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1939-4640.2000.tb03417.x"},{"key":"e_1_2_8_243_1","doi-asserted-by":"publisher","DOI":"10.1002\/med.21290"},{"key":"e_1_2_8_244_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2004.01.003"},{"key":"e_1_2_8_245_1","doi-asserted-by":"publisher","DOI":"10.1002\/macp.200700418"},{"key":"e_1_2_8_246_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.5b00427"},{"key":"e_1_2_8_247_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.0c01320"},{"key":"e_1_2_8_248_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1PY01075A"},{"key":"e_1_2_8_249_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6SC00615A"},{"key":"e_1_2_8_250_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8PY00012C"},{"key":"e_1_2_8_251_1","doi-asserted-by":"publisher","DOI":"10.1002\/ange.200702287"},{"key":"e_1_2_8_252_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612824666180213140732"},{"key":"e_1_2_8_253_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.polymer.2015.03.007"},{"key":"e_1_2_8_254_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.120078"},{"key":"e_1_2_8_255_1","doi-asserted-by":"publisher","DOI":"10.1080\/07388551.2020.1796576"},{"key":"e_1_2_8_256_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2023.116072"},{"key":"e_1_2_8_257_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2009.10.009"},{"key":"e_1_2_8_258_1","doi-asserted-by":"publisher","DOI":"10.1208\/s12248-014-9687-3"},{"key":"e_1_2_8_259_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201800354"},{"key":"e_1_2_8_260_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.160461"},{"key":"e_1_2_8_261_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.05558-11"},{"key":"e_1_2_8_262_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2012.08131.x"},{"key":"e_1_2_8_263_1","doi-asserted-by":"publisher","DOI":"10.3390\/idr15040046"},{"key":"e_1_2_8_264_1","doi-asserted-by":"publisher","DOI":"10.4155\/fmc-2019-0167"},{"key":"e_1_2_8_265_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.172.2.1169"},{"key":"e_1_2_8_266_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms8020280"},{"key":"e_1_2_8_267_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.2008\/022301-0"},{"key":"e_1_2_8_268_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.187.15.5387-5396.2005"},{"key":"e_1_2_8_269_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2018.04.014"},{"key":"e_1_2_8_270_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202001374"},{"key":"e_1_2_8_271_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2cs15273h"},{"key":"e_1_2_8_272_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.9b01278"},{"key":"e_1_2_8_273_1","doi-asserted-by":"publisher","DOI":"10.2217\/nnm.11.123"},{"key":"e_1_2_8_274_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.01401"},{"key":"e_1_2_8_275_1","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics11111591"}],"container-title":["Advanced Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/adbi.202400461","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/adbi.202400461","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/adbi.202400461","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T15:52:42Z","timestamp":1773244362000},"score":1,"resource":{"primary":{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/adbi.202400461"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,6]]},"references-count":275,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1002\/adbi.202400461"],"URL":"https:\/\/doi.org\/10.1002\/adbi.202400461","archive":["Portico"],"relation":{},"ISSN":["2701-0198","2701-0198"],"issn-type":[{"value":"2701-0198","type":"print"},{"value":"2701-0198","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,6]]},"article-number":"2400461"}}